Occlusive and Non-Occlusive Gastrointestinal Ischaemia: a Clinical Review with Special Emphasis on the Diagnostic Value of Tonometry

References

• Mohsenifar Z, Hay A, Hay J, Lewis MI, Koerner SK. Gastric intramural pH as a predictor of success or failure in weaning patients from mechanical ventilation. Ann Intern Med 1993; 119:794–8.
   Google Scholar
• Gutierrez G, Palizas F, Doglio G, et al. Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients. Lancet 1992;339:195–9.
   PubMed Web of Science ®Google Scholar
• Mythen MG, Webb AR. Intra-operative gut mucosal hypoperfusion is associated with increased postoperative complications and cost. Intens Care Med 1994;20:99–104.
   PubMed Web of Science ®Google Scholar
• Chang MC, Cheatham ML, Nelson LD, Rutherford EJ, Morris JA. Gastric tonometry supplements information provided by systemic indicators of oxygen transport. J Trauma 1994;37:488–94.
   Google Scholar
• Croft RJ, Menon GP, Marston A. Does “intestinal angina” exist? A critical study of obstructed visceral arteries. Br J Surg 1981;68:316–8.
   Google Scholar
• MacFarlane SD, Beebe HG. Progress in chronic mesenteric arterial ischemia. J Cardiovasc Surg 1989;30:178–84.
   PubMed Web of Science ®Google Scholar
• Marston A, Clarke JMF, Garcia Garcia J, Miller AL. Intestinal function and intestinal blood supply: a 20-year surgical study. Gut 1985;26:656–66.
   PubMedGoogle Scholar
• Nowicki PT, Stonestreet BS, Hansen NB, et al. Gastrointestinal blood flow and oxygen consumption in awake newborn piglets: effect of feeding. Am J Physiol 1983;245:G697–702.
   Google Scholar
• Perry M, Haedicke G, Bulkley G, Kvietys P, Granger D. Relation between acid secretion and blood flow in the canine stomach: role of oxygen consumption. Gastroenterology 1983; 85:529–34.
   Google Scholar
• Sidery MB, MacDonald IA, Blackshaw PE. Superior mesenteric artery blood flow and gastric emptying in humans and the differential effects of high fat and high carbohydrate meals. Gut 1994;35:186–90.
   Google Scholar
• Muller AF. Role of duplex Doppler ultrasound in the assessment of patients with postprandial abdominal pain. Gut 1992;33:460–5.
   PubMedGoogle Scholar
• Schlichtig R, Bowles SA. Distinguishing between aerobic and anaerobic appearance of dissolved CO2 in intestine during low flow. J Appl Physiol 1994;76:2443–51.
   PubMed Web of Science ®Google Scholar
• Nelson DP, King CE, Dodd SL, et al. Systemic and intestinal limits of O2 extraction in the dog. J Appl Physiol 1987;63:387–94.
   PubMed Web of Science ®Google Scholar
• Schlichtig R, Kramer DJ, Pinsky MR. Flow redistribution during progressive hemorrhage is a determinant of critical O2 delivery. J Appl Physiol 1991;70: 169–78.
   Google Scholar
• Reiner L, Jiminez FA, Rodriques FL. Atherosclerosis in the mesenteric circulation: observations and correlations with aortic and coronary atherosclerosis. Am Heart J 1963;66:200–9.
   Google Scholar
• Derrick JR, Pollard JC, Moore RM. The pattern of atherosclerotic narrowing of the celiac and mesenteric arteries. Ann Surg 1959;149:684–9.
   Google Scholar
• Järvinen O, Laurikka J, Sisto T, Salenius J-P, Tarkka MR. Atherosclerosis of the visceral arteries. Vasa 1995;24:9–14.
   Google Scholar
• Bron KM, Redman HC. Splanchnic artery stenosis and occlusion. Incidence; arteriographic and clinical manifestations. Radiology 1969;92:323–8.
   Google Scholar
• Dick AP. An arteriographic study of mesenteric arterial disease. Gut 1967;8:206–20.
   PubMedGoogle Scholar
• Stanton Jr PE, Hollier PA, Seidel TW, Rosenthal D, Clark M, Lamis PA. Chronic intestinal ischemia: diagnosis and therapy. J Vasc Surg 1986;4:338–44.
   PubMedGoogle Scholar
• Geelkerken RH, Van Bockel H, De Roos WK, Hermans J, Terpstra JL. Chronic mesenteric vascular syndrome. Arch Surg 1991;126:1101–6.
   PubMed Web of Science ®Google Scholar
• Zelenock GB, Graham LM, Whitehouse WM, et al. Splanchnic arteriosclerotic disease and intestinal angina. Arch Surg 1980;115:497–501.
   PubMedGoogle Scholar
• Crawford ES, Morris GC, Myhre HO, Roehm JOF. Celiac axis, superior mesenteric artery and inferior mesenteric artery occlusion: surgical considerations. Surgery 1977;82:856–66.
   PubMed Web of Science ®Google Scholar
• Jaxheimer EC, Jewell ER, Persson AV. Chronic intestinal ischemia: the Lahey Clinic approach to management. Surg Clin North Am 1985;65:123–30.
   Google Scholar
• Cormier JM, Fichelle JM, Vennin J, Laurian C, Gigou F. Atherosclerotic occlusive disease of the superior mesenteric artery: late results of reconstructive surgery. Ann Vasc Surg 1991;5:510–8.
   Google Scholar
• Rogers DM, Thompson JE, Garret WV, Talkington CM, Patman RD. Mesenteric vascular problems. Ann Surg 1982;195:554–65.
   Google Scholar
• Sitges Serra A, Mas X, Roqueta F, Figueras J, Sanz F. Mesenteric infarction: an analysis of 83 patients with prognostic studies in 44 cases undergoing a massive small bowel resection. Br J Surg 1988;75: 544–8.
   Google Scholar
• Whitehead R. The pathology of intestinal ischaemia. Clin Gastroenterol 1972;1:613–20.
   Google Scholar
• Schneider TA, Longo WE, Ure T, Vernava AM. Mesenteric ischemia: acute arterial syndromes. Dis Colon Rectum 1994; 37:1163–74.
   PubMed Web of Science ®Google Scholar
• Bokobza B, Leblanc I, Seyer J, Michot F, Teniere P. Acute intestinal ischemia due to arterial thrombosis. Value of emergency arteriography and revascularization. J Mal Vasc 1988;13:356–8.
   Google Scholar
• Clark RA, Gallant TE. Acute mesenteric ischemia: angiographic spectrum. AJR 1984;142:555–62.
   PubMedGoogle Scholar
• Blair NP, Hayes GW. Perforation of the small bowel: a case report. Can J Surg 1995;38:281–2.
   PubMedGoogle Scholar
• Hendel RC, Cuenoud HF, Giansiracusa DF, Alpert JS. Multiple cholesterol emboli syndrome. Bowel infarction after retrograde angiography. Arch Intern Med 1989;149:2371–4.
   Google Scholar
• Holly DC, Zachary PE. Cholesterol embolization leading to small and large bowel infarction. Am J Gastroenterol 1995;90:2075–6.
   PubMedGoogle Scholar
• Levy PJ, Manny J. Mesenteric infarction following angiography. Review of the literature with additional two case reports. Vasc Surg 1993;27:689–95.
   Google Scholar
• Boley SJ, Brandt LJ, Veith FJ. Ischemic disorders of the intestines. Curr Probl Surg 1978;15:1–85.
   PubMedGoogle Scholar
• Harjola PT. A rare obstruction of the coeliac artery. Ann Chir Gynaecol Fenn 1963;52:547–9.
   PubMedGoogle Scholar
• Loffeld RJLF, Overtoom HAJM, Rauwerda JA. The celiac axis compression syndrome, report of five cases. Digestion 1995;56:534–7.
   Google Scholar
• Geelkerken RH, Van Bockel JH, De Roos WK, Hermans J. Coeliac artery compression syndrome: the effect of decompression. Br J Surg 1990;77:807–9.
   PubMedGoogle Scholar
• Brandt LJ, Boley SJ. Celiac axis compression syndrome: a critical review. Dig Dis Sci 1978;23:633–40.
   Google Scholar
• Reuter SR, Olin T. Stenosis of the celiac artery. Radiology 1965;85:617–27.
   Google Scholar
• Camilleri M, Pusey CD, Chadwick VS, Rees AJ. Gastrointestinal manifestations of systematic vasculitis. Q J Med 1983;52:141–9.
   PubMedGoogle Scholar
• Hatzinicolaou P, Vayopoulos G, Mavropoulos S, et al. Vascular manifestations in Behcets disease. Br J Rheumatol 1992;31:284–5.
   PubMedGoogle Scholar
• Du LH, Wechsler B, Guillevin L, et al. Gastrointestinal manifestations of periarteritis nodosa in a series of 120 patients. Gastroenterol Clin Biol 1985;9:697–703.
   PubMedGoogle Scholar
• Gore RM, Marn CS, Ujii GT, Craig RM, Marquardt J. Ischemic colitis associated with systemic lupus erythematosus. Dis Colon Rectum 1983;26:449–51.
   PubMed Web of Science ®Google Scholar
• Gorton M, John Jr J. Polyarteritis overlap syndrome with extensive bowel infarction. Am J Gastroenterol 1980;74:153–6.
   PubMedGoogle Scholar
• Kistin MG, Kaplan MM, Harrington JT. Diffuse ischemic colitis associated with systemic lupus erythematosus—response to subtotal colectomy. Gastroenterology 1978;75:1147–51.
   Google Scholar
• Sauvaget F, Debray M, Herve de Sigalony J-P, et al. Colonic ischemia reveals thromboangiitis obliterans (Buerger’s disease). Gastroenterology 1996;110:900–3.
   PubMed Web of Science ®Google Scholar
• Bienenstock H, Minick R, Rogoff B. Mesenteric arteritis and intestinal infarction in rheumatoid disease. Arch Intern Med 1967;119:359–64.
   Google Scholar
• Abdu RA, Zakhour BJ, Dallis DJ. Mesenteric venous thrombosis—1911 to 1984. Surgery 1986;101: 383–8.
   Google Scholar
• Haddad MC, Clark DC, Sharif HS, Al Shahed M, Aideyan O, Sammak BM. MR, CT, and ultrasonography of splanchnic venous thrombosis. Gastrointest Radiol 1992;17:34–40.
   PubMedGoogle Scholar
• Gollin G, Ward B, Meier GH, Sumpio BE, Gusberg RJ. Central splanchnic venous thrombosis: often unsuspected, usually uncomplicated. J Clin Gastroenterol 1994;18:109–13.
   Google Scholar
• Harward TRS, Green D, Bergan JJ, Rizzo RJ, Yao JST. Mesenteric venous thrombosis. J Vasc Surg 1989;9:328–33.
   PubMed Web of Science ®Google Scholar
• Clavien PA, Durig M, Harder F. Venous mesenteric infarction: a particular entity. Br J Surg 1988;75:252–5.
   Google Scholar
• Green D, Ganger DR, Blei AT. Protein C deficiency in splanchnic venous thrombosis. Am J Med 1987;82:1171–4.
   Google Scholar
• Lock G, Scholmerich J. Non-occlusive mesenteric ischemia. Hepato Gastroenterol 1995;42:234–9.
   PubMedGoogle Scholar
• Doglio GR, Pusajo JF, Egurrola MA, et al. Gastric mucosal pH as a prognostic index of mortality in critically ill patients. Crit Care Med 1991;19:1037–40.
   PubMed Web of Science ®Google Scholar
• Gys T, Hubens A, Neels H, Lauwers L, Peeters R. Prognostic value of gastric intramural pH in surgical intensive care patients. Crit Care Med 1988;16:1222–4.
   Google Scholar
• Mythen MG, Purdy G, Mackie IJ, McNally T, Webb AR, Machin SJ. Postoperative multiple organ dysfunction syndrome associated with gut mucosal hypoperfusion, increased neutrophil degranulation and C1-esterase inhibitor depletion. Br J Anaesthesiol 1993;71:858–63.
   PubMed Web of Science ®Google Scholar
• Maynard N, Bihari D, Beale R, et al. Assessment of splanchnic oxygenation by gastric tonometry in patients with acute circulatory failure. J Am Med Assoc 1993;270:1203–10.
   PubMed Web of Science ®Google Scholar
• Fiddian-Green RG. Associations between intramucosal acidosis in the gut and organ failure. Crit Care Med 1993;21: S103–7.
   Google Scholar
• Qamar MI, Read AE. Effects of exercise on mesenteric blood flow in man. Gut 1987;28:583–7.
   PubMed Web of Science ®Google Scholar
• Moses FM. The effect of exercise on the gastrointestinal tract. Sports Med 1990;9:159–72.
   PubMed Web of Science ®Google Scholar
• Nielsen HB, Svendsen LB, Jensen TH, Secher NH. Exercise induced gastric mucosal acidosis. Med Sci Sports Exer 1995; 27:1003–6.
   PubMed Web of Science ®Google Scholar
• Heer M, Repond F, Hany A, et al. Acute ischaemic colitis in a female long distance runner. Gut 1987;28:896–9.
   PubMed Web of Science ®Google Scholar
• Fink MP. Gastrointestinal mucosal injury in experimental models of shock, trauma, and sepsis. Crit Care Med 1991;19:627–41.
   PubMed Web of Science ®Google Scholar
• Kivilaakso E, Kiviluoto T, Mustonen H, Paimela H. Gastric mucosal acid-base balance. J Int Med 1990;228:S63–8.
   Google Scholar
• Leung FW, Itoh M, Hirabayashi K, Guth PH. Role of blood flow in gastric and duodenal mucosal injury in the rat. Gastroenterology 1985;88:281–9.
   PubMed Web of Science ®Google Scholar
• Smith SM, Holm-Rutili L, et al. Role of neutrophils in hemorrhagic shock-induced gastric mucosal injury in the rat. Gastroenterology 1987;93:466–71.
   PubMed Web of Science ®Google Scholar
• Kaleya RN, Sammartano RJ, Boley SJ. Aggressive approach to acute mesenteric ischemia. Surg Clin North Am 1992;72:157–82.
   Google Scholar
• Bergan JJ, Dean RH, Conn JR, Yao JST. Revascularisation in the treatment of mesenteric infarction. Ann Surg 1975;182:430–8.
   PubMedGoogle Scholar
• Järvinen O, Laurikka J, Salenius JP, Tarkka M. Acute intestinal ischaemia. A review of 214 cases. Ann Chir Gynaecol 1994;83: 22–5.
   Google Scholar
• Hunter GC, Guernsey JM. Mesenteric ischemia. Med Clin North Am 1988;72:1091–115.
   PubMedGoogle Scholar
• Batellier J, Kieny R. Superior mesenteric artery embolism: Eighty-two cases. Ann Vasc Surg 1990;4:112–6.
   PubMedGoogle Scholar
• Babu SC, Shah PM. Celiac territory ischemic syndrome in visceral artery occlusion. Am J Surg 1993;166:227–30.
   PubMedGoogle Scholar
• Casey KM, Quigley TM, Kozarek RA, Raker EJ. Lethal nature of ischemic gastropathy. Am J Surg 1993;165:646–9.
   PubMedGoogle Scholar
• Cherry RD, Jabbari M, Goresky CA, et al. Chronic mesenteric vascular insufficiency with gastric ulceration. Gastroenterology 1986;91:1548–52.
   PubMedGoogle Scholar
• Fiddian-Green RG, Stanley JC, Nostrant T, Phillips D. Chronic gastric ischemia; a cause of abdominal pain or bleeding identified from the presence of gastric mucosal acidosis. J Cardiovasc Surg 1989;30:852–9.
   Google Scholar
• Liberski SM, Koch KL, Atnip RG, Stern RM. Ischemic gastroparesis: resolution after revascularization. Gastroenterology 1990;99:252–7.
   PubMedGoogle Scholar
• Wittenberg J, Athanasoulis A, Williams LF, Paredes S, O’Sullivan P, Brown B. Ischemic colitis: radiology and pathophysiology. AJR 1975;123:287–300.
   Google Scholar
• Parish KL, Chapman WC, Williams LJ. Ischemic colitis: An ever-changing spectrum? Am Surg 1991;57:118–21.
   Google Scholar
• Ottinger LW, Austen WG. A study to 136 patients with mesenteric infarction. Surg Gynecol Obstet 1967;124:251–61.
   PubMedGoogle Scholar
• Iida M, Matsui T, Fuchigami T, et al. Ischemic colitis: serial changes in double-contrast barium enema examination. Radiology 1986;159:337–42.
   PubMedGoogle Scholar
• Reeders JWAJ Ischaemic colitis. Amsterdam: University of Amsterdam, 1984.
   Google Scholar
• Scherpenisse J, van Hees PAM. The endoscopic spectrum of colonic mucosal injury following aortic aneurysm resection. Endoscopy 1989;21:174–6.
   PubMed Web of Science ®Google Scholar
• Longo WE, Lee TC, Barnett MG, et al. Ischemic colitis complicating abdominal aortic aneurysm surgery in the U.S. veteran. J Surg Res 1996;60:351–4.
   PubMed Web of Science ®Google Scholar
• Guttormson NL, Bubrick MP. Mortality from ischemic colitis. Dis Colon Rectum 1989;32:469–72.
   PubMed Web of Science ®Google Scholar
• Bast TJ, Van Der Biezen JJ, Scherpenisse J, Eikelboom BC. Ischaemic disease of the colon and rectum after surgery for abdominal aortic aneurysm: a prospective study of the incidence and risk factors. Eur J Vasc Surg 1990;4:253–7.
   PubMedGoogle Scholar
• Maupin GE, Rima SD, Villalba M. Ischemic colitis following abdominal aortic reconstruction for ruptured aneurysm. A 10-year experience. Am Surg 1989;55: 378–80.
   Google Scholar
• Welling RE, Roedersheimer LR, Arbaugh JJ, Cranley JJ. Ischemic colitis following repair of ruptured abdominal aortic aneurysm. Arch Surg 1985;120:1368–70.
   PubMedGoogle Scholar
• Bower TC. Ischemic colitis. Surg Clin North Am 1993;73:1037–53.
   PubMedGoogle Scholar
• Igarashi M, Katsumata T, Yamamoto Y, et al. Clinical and endoscopic study of ischemic colitis. Dig Endosc 1990;2:305–314.
   Google Scholar
• Boley SJ, Kaleya RN, Brandt LJ. Mesenteric venous thrombosis. Surg Clin North Am 1992;72:183–201.
   PubMed Web of Science ®Google Scholar
• Sakio H, Ohtsu S, Okuda C. How should we treat intestinal ischemia? 1: Effects of dobutamine and dopamine. Jpn J Anesthesiol 1994;43: 1304–9.
   Google Scholar
• Marik PE, Mohedin M. The contrasting effects of dopamine and norepinephrine on systemic and splanchnic oxygen utilization in hyperdynamic sepsis. J Am Med Assoc 1994;272:1354–7.
   PubMed Web of Science ®Google Scholar
• Silverman HJ, Tuma P. Gastric tonometry in patients with sepsis. Effects of dobutamine infusions and packed red blood cell transfusions. Chest 1992;102:184–8.
   Google Scholar
• Smithies M, Yee TH, Jackson L, Beale R, Bihari D. Protecting the gut and the liver in the critically ill: effects of dopexamine. Crit Care Med 1994;22:789–95.
   Google Scholar
• Radermacher P, Buhl R, Santak B, et al. The effects of prostacyclin on gastric intramucosal pH in patients with septic shock. Int Care Med 1995;21:414–21.
   PubMed Web of Science ®Google Scholar
• Bulkley GB, Oshima A, Bailey RW, Horn SD. Control of gastric vascular resistance in cardiogenic shock. Surgery 1985;98:213–22.
   PubMedGoogle Scholar
• Cullen JJ, Ephgrave KS, Broadhurst KA, Booth B. Captopril decreases stress ulceration without affecting gastric perfusion during canine hemorrhagic shock. J Trauma 1994;37:43–9.
   PubMedGoogle Scholar
• Downey HF, Crystal GJ, Bashour FA. Regional renal and splachnic blood flows during nicotine infusion: effects of alpha and combined alpha and beta blockade. J Pharm Exp Ther 1982;220:375–81.
   Google Scholar
• Gallavan RH, Tsuchiya Y, Jacobson ED. Effects of nicotine on canine intestinal blood flow and oxygen consumption. Am J Physiol 1984;246:G195–203.
   Google Scholar
• Hollier LH, Bernatz PE, Pairolero PC, Payne WS, Osmundson PA. Surgical management of chronic visceral ischemia: a reappraisal. Surgery 1981;90:940–6.
   Google Scholar
• Pokrovsky AV, Kasantchjan PO. Surgical treatment of chronic occlusive disease of the enteric visceral branches of the abdominal aorta; experience with 119 operations. Ann Surg 1978;191:51–6.
   Google Scholar
• Reilly LM, Ammar AD, Stoney RJ, Ehrenfeldd WK. Late results following operative repair for celiac artery compression syndrome. J Vasc Surg 1985;2:79–91.
   PubMed Web of Science ®Google Scholar
• Harris MT, Lewis BS. Systemic diseases affecting the mesenteric circulation. Surg Clin North Am 1992;72:245–59.
   PubMedGoogle Scholar
• Gandhi SK, Hanson MM, Vernava AM, Kaminski DL, Longo WE. Ischemic colitis. Dis Colon Rectum 1996;39:88–100.
   PubMed Web of Science ®Google Scholar
• Fisher Jr DF, Fry WJ. Collateral mesenteric circulation. Surg Gynecol Obstet 1987;164:487–92.
   PubMedGoogle Scholar
• Kurland B, Brandt LJ, Delany HM. Diagnostic tests for intestinal ischemia. Surg Clin North Am 1992;72:85–105.
   PubMedGoogle Scholar
• Kanda T, Fujii H, Tani T, et al. Intestinal fatty acid-binding protein is a useful diagnostic marker for mesenteric infarction in humans. Gastroenterology 1996;110:339–43.
   PubMed Web of Science ®Google Scholar
• Bowersox JC, Zwolak RM, Walsh DB, et al. Duplex ultrasonography in the diagnosis of celiac and mesenteric artery occlusive disease. J Vasc Surg 1991;14:780–8.
   PubMedGoogle Scholar
• Moneta GL, Yeager RA, Dalman R, Antonovic R, Hall LD, Porter JM. Duplex ultrasound criteria for diagnosis of splanchnic artery stenosis or occlusion. J Vasc Surg 1991;14:511–20.
   PubMed Web of Science ®Google Scholar
• Harward TRS, Smith S, Seeger JM. Detection of celiac axis and superior mesenteric artery occlusive disease with use of abdominal duplex scanning. J Vasc Surg 1993;17:738–45.
   Google Scholar
• Moneta GL, Lee RW, Yeager RA, et al. Mesenteric duplex scanning: a blinded prospective study. J Vasc Surg 1993;17:79–86.
   PubMed Web of Science ®Google Scholar
• Roobottom CA, Dubbins PA. Significant disease of the celiac and superior mesenteric arteries in asymptomatic patients: predictive value of Doppler sonography. AJR 1993;161:985–8.
   PubMedGoogle Scholar
• Wheatley AM. Limitations of laser-Doppler velocimetry and reflectance spectrophotometry estimating gastric mucosal blood flow. Am J Physiol 1993;263:G595–7.
   Google Scholar
• Taha AS, Angerson W, Nakshabendi I, et al. Gastric and duodenal mucosal blood flow in patients receiving nonsteroidal anti-inflammatory drugs—influence of age, smoking, ulceration and Helicobacter pylori. Aliment Pharmacol Therap 1993;7:41–5.
   PubMedGoogle Scholar
• Konturek JW, Dembinski A, Stoll R, Konturek M, Domschke W. Gastric mucosal blood flow and neutrophil activation in aspirin-induced gastric mucosal damage in man. Scand J Gastroenterol 1993;28:767–71.
   Google Scholar
• Iwao T, Toyonaga A, Ikegami M, et al. Gastric mucosal blood flow after smoking in healthy human beings assessed by laser Doppler flowmetry. Gastrointest Endosc 1993;39:400–3.
   PubMed Web of Science ®Google Scholar
• Larson MV, Ahlquist DA, Karlstrom L, Sarr MG. Intraluminal measurement of enteric mucosal perfusion: relationship to superior mesenteric artery flow during basal and postprandial states in the dog. Surgery 1994;115:118–26.
   PubMed Web of Science ®Google Scholar
• Ohri SK, Somasundaram S, Koak Y, et al. The effect of intestinal hypoperfusion on intestinal absorption and permeability during cardiopulmonary bypass. Gastroenterology 1994; 106:318–23.
   PubMed Web of Science ®Google Scholar
• Tollefson DFJ, Wright DJ, Reddy DJ, Kintanar EB. Intraoperative determination of intestinal viability by pulse oximetry. Ann Vasc Surg 1995;9:357–60.
   PubMedGoogle Scholar
• Avino AJ, Oldenburg WA, Gloviczki P, et al. Inferior mesenteric venous sampling to detect colonic ischemia: a comparison with laser Doppler flowmetry and photoplethysmography. J Vasc Surg 1995;22:271–9.
   PubMedGoogle Scholar
• MacDonald PH, Dinda PK, Beck IT, Mercer CD. The use of oximetry in determining intestinal blood flow. Surg Gynecol Obstet 1993;176:451–8.
   PubMedGoogle Scholar
• Vahl AC, van Rij GL, Visser JJ, et al. Endoluminal pulse oximetry in ischemic colon in a swine model. J Am Coll Surg 1995;180:57–64.
   PubMedGoogle Scholar
• Heard SO, Baum TD, Wang H, Rothschild HR, Fink MP. Systemic and mesenteric O2 metabolism in endotoxic pigs: effect of graded hemorrhage. Circ Shock 1991;35: 44–52.
   Google Scholar
• Montgomery A, Almqvist P, Arvidsson D, Lindgren S, Haglund U. Early detection of gastrointestinal mucosal ischemia in porcine E. coli sepsis. Acta Chir Scand 1990;156:613–20.
   Google Scholar
• Rasmussen I, Haglund U. Early gut ischemia in experimental fecal peritonitis. Circ Shock 1992;38:22–8.
   PubMedGoogle Scholar
• Diebel LN, Dulchavsky SA, Wilson RF. Effect of increased intra-abdominal pressure on mesenteric arterial and intestinal mucosal blood flow. J Trauma 1992;33:45–8.
   Google Scholar
• Salzman AL, Wang H, Wollert PS, et al. Endotoxin-induced ileal mucosal hyperpermeability in pigs: role of tissue acidosis. Am J Physiol 1994;266:G633–46.
   PubMed Web of Science ®Google Scholar
• Antonsson JB, Haglund UH. Gut intramucosal pH and intraluminal PO2 in a porcine model of peritonitis or haemorrhage. Gut 1995;37:791–7.
   PubMed Web of Science ®Google Scholar
• Fink MP, Kaups KL, Wang H, Rothschild HR. Maintenance of superior mesenteric arterial perfusion prevents increased intestinal mucosal permeability in endotoxic pigs. Surgery 1991;110:154–61.
   PubMed Web of Science ®Google Scholar
• Boros M, Kaszaki J, Ordogh B, Nagy S. Intramucosal pH changes following complete segmental small intestinal ischemia, as compared with the effects of superior mesenteric artery occlusion. Eur Surg Res 1994;26:76–86.
   PubMedGoogle Scholar
• Sakio H, Ohtsu S, Okuda C. Gastrointestinal mucosal ischemia in hemorrhagic shock—measurement with tonometer. Jpn J Anesthesiol 1993;42:195–200.
   Google Scholar
• Ohri SK, Becket J, Brannan J, Keogh BE, Taylor KM. Effects of cardiopulmonary bypass on gut blood flow, oxygen utilization, and intramucosal pH. Ann Thor Surg 1994;57:1193–9.
   Google Scholar
• Schlichting E, Lyberg T. Monitoring of tissue oxygenation in shock: an experimental study in pigs. Crit Care Med 1995;23:1703–10.
   PubMedGoogle Scholar
• Fiddian-Green RG, Amelin PM, Herrmann JB, et al. Prediction of the development of sigmoid ischemia on the day of aortic operations. Arch Surg 1986;121:654–60.
   Google Scholar
• Roumen RMH, Vreugde JPC, Goris RJA. Gastric tonometry in multiple trauma patients. J Trauma 1994;36:313–6.
   Google Scholar
• Wood PR, Cudworth P, Davies GE, Lawler PG. Potential hazards in estimation of gastric intramucosal pH. Lancet 1992;340:913.
   PubMedGoogle Scholar
• Riddington D, Venkatesh B, Clutton-Brock T, et al. Potential hazards in estimation of gastric intramucosal pH. Lancet 1992;340:547.
   Google Scholar
• Crispin C, Jones W, Daffurn K. How consistently do RNs perform the procedure of collecting specimens for measurement of gastric pHi and CO2? Int Crit Care Nurs 1995;11: 123–5.
   Google Scholar
• Kolkman JJ, Zwarekant LJ, Boshuizen K, Steverink PJGM, Groeneveld ABJ, Meuwissen SGM. Type of solution and PCO2 measurement errors during tonometry. Int Care Med 1997; 23:658–63.
   PubMedGoogle Scholar
• Knichwitz G, Mertes N, Kuhmann M. Improved PCO2 measurement in six standard blood gas analysers using a phosphate-buffered solution for gastric tonometry. Anaesthesia 1995;50: 532–4.
   Google Scholar
• Riddington D, Vankatesh KB, Clutton-Brock T, Bion J. Measuring carbon dioxide tension in saline and alternative solutions: quantification of bias and precision in two blood gas analyzers. Crit Care Med 1994;22:96–100.
   Google Scholar
• Kolkman JJ, Zwarekant LJ, Boshuizen K, Groeneveld ABJ, Meuwissen SGM. In vitro evaluation of intragastric PCO2 measurement by air tonometry. J Clin Monit 1997;13: 115–9.
   Google Scholar
• Kolkman JJ, Groeneveld aBj, Meuwissen SGM. Effect of ranitidine on basal and bicarbonate enhanced intragastric PCO2: a tonometric study. Gut 1994;35: 737–41.
   Google Scholar
• Kolkman JJ, Groeneveld ABJ, Meuwissen SGM. Gastric PCO2 tonometry is independent of carbonic anhydrase inhibition. Dig Dis Sci 1997;42: 99–102.
   Google Scholar
• Parviainen I, Vaisanen O, Ruokonen E, Takala J. Effect of nasogastric suction and ranitidine on the calculated gastric intramucosal pH. Int Care Med 1996;22:319–23.
   PubMedGoogle Scholar
• Bams JJ, Kolkman JJ, Roukens MP, et al. Postoperative gastric acid secretion failure after coronary-artery bypass surgery is not associated with gastric ischemia. Gastroenterology 1996;110:A311.
   PubMedGoogle Scholar
• Geus WP Long-term intragastric pH monitoring in intensive care patients [Thesis]. Leiden, 1993.
   Google Scholar
• Groeneveld ABJ, Kolkman JJ. Splanchnic tonometry: a review of physiology, methodology, and clinical applications. J Crit Care 1994;9:198–210.
   PubMed Web of Science ®Google Scholar
• Desai VS, Weil MH, Tang WC, Yang G, Bisera J. Gastric intramural PCO2 during peritonitis and shock. Chest 1993;104: 1254–8.
   Google Scholar
• Tang W, Weil MH, Sun S, Noc M, Gazmuri RJ, Bisera J. Gastric intramural PCO2 as monitor of perfusion failure during hemorrhagic and anaphylactic shock. J Appl Physiol 1994;76:572–7.
   PubMedGoogle Scholar
• Benjamin E, Polokoff E, Oropello JM, Leibowitz AB, Iberti TJ. Sodium bicarbonate administration affects the diagnostic accuracy of gastrointestinal tonometry in acute mesenteric ischemia. Crit Care Med 1992;20:1181–3.
   Google Scholar
• Baigorri F, Mas A, Calvet X, et al. Effect of hypercapnia on the determination of the gastric intramucosal pH. Med Intens 1995;19:239–44.
   Google Scholar
• Schlichtig R, Mehta N, Gayowski JP. Tissue-arterial PCO2 difference is a better marker of ischemia than intramural pH (pHi) or arterial pH–pHi difference. J Crit Care 1996;11: 51–6.
   Google Scholar
• Antonsson JB, Boyle CC, Kruithoff KL, et al. Validation of tonometric measurement of gut intramural pH during endotoxemia and mesenteric occlusion in pigs. Am J Physiol 1990;259:G519–23.
   PubMed Web of Science ®Google Scholar
• Boley SJ, Brandt LJ, Veith FJ, Kosches D, Sales C. A new provocative test for chronic mesenteric ischemia. Am J Gastroenterol 1991;86:888–91.
   PubMed Web of Science ®Google Scholar
• Geelkerken RH, Schultze Kool LJ, Hermans J, Zarza MT, van Bockel JH. Chronic splanchnic syndrome: tonometry as a functional test. Eur J Surgery 1997;163:115–21.
   PubMedGoogle Scholar
• Kolkman JJ, Groeneveld AbJ, Meuwissen SGM. Gastric tonometry during a standardized test meal is dependent upon adequate acid suppression and timing of measurement. Gastroenterology 1995;108:A133.
   Google Scholar
• Kolkman JJ, Groeneveld ABJ, vd Berg FG, Rauwerda JA, Meuwissen SGM. Gastric PCO2 tonometry during exercise: a promising tool for detection and grading of gastric ischemia. Gastroenterology 1996;110:A338.
   Google Scholar