13
Views
9
CrossRef citations to date
0
Altmetric
Research Article

Maximal Gastric Acid Secretion in Man: A Concept That Needs Precision

Pages 1009-1015 | Published online: 08 Jul 2009

References

  • Beaumont W. Experiments and observations on the gastric juice and the physiology of digestion. Plattsburg (NY): F. P. Allen; 1833.
  • Pavlov IP. The work of the digestive glands. 2nd ed. London: Griffin; 1910.
  • Kirsner JB, Bock D, Palmer WL, Levin E, Ford H. Variations in basal gastric secretion in man and the evaluation of gastric secretory stimulants. Gastroenterology 1956;30:779–9.
  • Kay AW. Effect of large doses of histamine on gastric secretion of HCl. Br Med J 1953;2:77–80.
  • Makhlouf GM, McManus JPA, Card WI. Action of pentapeptide (ICI 50 123) on gastric secretion in man. Gastroenterology 1966;51: 455–65.
  • Marks IN, Komarov SA, Shay H. Maximal acid secretory response to histamine and its relation to parietal cell mass in the dog. Am J Physiol 1960;199:579–88.
  • Aubrey DA, Forrest APM. Effects of histamine acid phosphate and pentagastrin on gastric secretion in normal human subjects. Gut 1970;11:395–404.
  • Pevsner L, Grossman MI. The mechanism of vagal stimulation of gastric acid secretion. Gastroenterology 1955;28:493–9.
  • Stempien SJ. Insulin gastric analysis: technic and interpretations. Am J Dig Dis 1962;7:138–52.
  • Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984;1:1312–5.
  • Levi S, Beardshall K, Haddad G, Playford R, Ghosh P, Calam J. Campylobacter pylori and duodenal ulcers: the gastrin link. Lancet 1989;1:1167–8.
  • Waldum HL, Arnestad JS, Brenna E, Eide I, Syversen U, Sandvik AK. Marked increase in gastric acid secretory capacity after omeprazole treatment. Gut 1996;39:649–53.
  • El-Omar EM, Penman ID, Spence E, Ardill JES, McColl KEL. The GRP test: a new clinical test of acid secretion—reproducibility data. Eur J Gastroenterol Hepatol 1994;6:417–21.
  • Waldum HL, Sandvik AK, Brenna E, Petersen H. Gastrinhistamine sequence in the regulation of gastric acid secretion. Gut 1991;32:698–701.
  • Håkanson R, Owman CH. Argyrophilic reaction of histamine- containing epithelial cells in murine gastric mucosa. Experientia 1969;25:625–6.
  • Waldum HL, Sandvik AK, Syversen U, Brenna E. The enterochromaffin-like (ECL) cell. Physiological and pathophysiological role. Acta Oncol 1993;32:141–7.
  • Kahlson G, Rosengren E, Svahn D, Thunberg R. Mobilization and formation of histamine in the gastric mucosa as related to acid secretion. J Physiol 1964;174:400–16.
  • Håkanson R, Kroesen JH, Liedberg G, Oscarson J, Rehfeld JF, Stadil F. Correlation between serum gastrin concentration and rat stomach histidine decarboxylase activity. J Physiol 1974; 243:483–98.
  • Dimaline R, Sandvik AK. Histidine decarboxylase gene expression in rat fundus is regulated by gastrin. FEBS Lett 1991;281:20–2.
  • Sandvik AK, Waldum HL, Kleveland PM, Schulze Søgnen B. Gastrin produces an immediate and dose-dependent histamine release preceding acid secretion in the totally isolated, vascularly perfused rat stomach. Scand J Gastroenterol 1987; 22:803–8.
  • Waldum HL, Sandvik AK, Brenna E. Gastrin: Histamine-releasing activity. In: Walsh JH, editor. Gastrin. New York: Raven Press; 1993. p. 259–71.
  • Brenna E, Waldum HL. Studies of isolated parietal and enterochromaffin-like cells from the rat. Scand J Gastroenterol 1991; 26:1295–306.
  • Mårvik R, Sandvik AK, Waldum HL. Gastrin stimulates histamine release from the isolated pig stomach. Scand J Gastroenterol 1997;32:2–5.
  • Gerber JG, Scott Barnes J. Histamine release in vivo by pentagastrin from the canine stomach. J Pharmacol Exp Ther 1987; 243:887–92.
  • Lonroth H, Rosengren E, Olbe L, Lundell L. Histamine metabolism in human gastric mucosa. Effect of pentagastrin stimulation. Gastroenterology 1990;98:921–8.
  • Miyazaki Y, Imamura I, Shinomura Y, Wada H, Tarui S. Marked increase in gastric histidine decarboxylase activity in patients with hypergastrinemia. Life Sci 1991;48:51–8.
  • Nakata H, Matsui T, Ito M, Taniguchi T, Naribayashi Y, Arima N, et al. Cloning and characterization of gastrin receptor from ECL carcinoid tumor of mastomys natalensis. Biochem Biophys Res Commun 1992;187:1151–7.
  • Kleveland PM, Waldum HL, Larsson H. Gastric acid secretion in the totally isolated, vascularly perfused rat stomach. Scand J Gastroenterol 1987;22:705–13.
  • Bergqvist E, Öbrink KJ. Gastrin-histamine as a normal sequence in gastric acid stimulation in the rabbit. Upsala J Med Sci 1979;84:145–54.
  • Kopin AS, Lee YM, McBride EW, Miller LJ, Lu M, Lin HY, et al. Expression cloning and characterization of the canine parietal cell gastrin receptor. Proc Natl Acad Sci 1992;89:3605–9.
  • Kulaksiz H, Arnold R, Fossmann WG, Göke B, Eissele R. Cellular localization of CCK-B/gastrin receptor in the human stomach by immunohistochemistry and by in situ reverse transcriptase: polymerase chain reaction. Gastroenterology 1998; 114:A1156–7.
  • Kajimura M, Reuben MA, Sachs G. The muscarinic receptor gene expressed in rabbit parietal cells is the m3 subtype. Gastroenterology 1992;103: 870–5.
  • Soll AH. Secretagogue stimulation of [14C]aminopyrine accumulation by isolated canine parietal cells. Am J Physiol 1980; 238:366–75.
  • Sandvik AK, Kleveland PM, Waldum HL. Muscarinic M2 stimulation releases histamine in the totally isolated, vascularly perfused rat stomach. Scand J Gastroenterol 1988;23: 1049–56.
  • Sandvik AK, Mdrvik R, Dimaline R, Waldum HL. Carbachol stimulates acid secretion in the rat by a direct effect on the parietal cell. Br J Pharmacol 1998;124:69–74.
  • Vallgren S, Ekelund M, Hdkanson R. Mechanism of inhibition of gastric acid secretion by vagal denervation in the rat. Acta Physiol Scand 1983;119:77–80.
  • Roland M, Berstad A, Liavag I. Acid and pepsin secretion in duodenal ulcer patients in response to graded doses of pentagastrin or pentagastrin and carbocholine before and after proximal gastric vagotomy. Scand J Gastroenterol 1974;9:511–8.
  • Broomé A, Bergstrom H, Olbe L. Maximal acid response to histamine in duodenal ulcer patients subjected to resection of the antrum and duodenal bulb followed by vagotomy. Gastroenterology 1967;52:952–8.
  • Leth R, Elander B, Fellenius E, Olbe L, Haglund U. Effect of proximal gastric vagotomy and antrectomy on parietal cell function in humans. Gastroenterology 1984;87:1277–82.
  • Waldum HL, Lehy T, Brenna E, Sandvik AK, Petersen H, Schulze Søgnen B, et al. Effect of the histamine-1 antagonist astemizole alone or with omeprazole on rat gastric mucosa. Scand J Gastroenterol 1991;26: 23–35.
  • McGuigan JE, Trudeau WL. Studies with antibodies to gastrin. Radioimmunoassay in human serum and physiological studies. Gastroenterology 1970;58:139–50.
  • Walsh JW, Richardson CT, Fordtran JS. pH dependence of acid secretion and gastrin release in normal and ulcer subjects. J Clin Invest 1975;55:462–8.
  • Saffouri B, Weir GC, Bitar KN, Makhlouf GM. Stimulation of gastrin secretion from the vascularly perfused rat stomach by somatostatin antiserum. Life Sci 1979;20:1–49.
  • Impicciatore M, Walsh JH, Grossman MI. Low doses of atropine enhance serum gastrin response to food in dogs. Gastroenterology 1977;72:995–6.
  • Walsh JH. Hypergastrinemia develops within 24 hours of truncal vagotomy in dogs. Gastroenterology 1985;88:35–40.
  • Varner AA, Modlin IM, Walsh JH. High potency of bombesin for stimulation of human gastrin release and gastric acid secretion. Regul Pept 1981;1:289–96.
  • Hirschowitz BI, Molina E. Relation of gastric acid and pepsin secretion to serum gastrin levels in dogs given bombesin and gastrin-17. Am J Physiol 1983;244:G546–51.
  • Sandvik AK, Holst JJ, Waldum HL. The effect of gastrinreleasing peptide on acid secretion and the release of gastrin, somatostatin, and histamine in the totally isolated, vascularly perfused rat stomach. Scand J Gastroenterol 1989;24:9–15.
  • Sandvik AK, Waldum HL. The effect of somatostatin on baseline and stimulated acid secretion and vascular histamine release from the totally isolated vascularly perfused rat stomach. Regul Pept 1988;20:233–9.
  • Berglindh T, Helander HF, Öbrink KJ. Effects of secretagogues on oxygen consumption, aminopyrine accumulation and morphology in isolated gastric glands. Acta Physiol Scand 1976; 97:404–14.
  • Soll AH. The actions of secretagogues on oxygen uptake by isolated mammalian parietal cells. J Clin Invest 1978;61:370–80.
  • Ecknauer R, Dial E, Thompson WJ, Johnson LR, Rosenfeld GC. Isolated rat gastric parietal cells: cholinergic response and pharmacology. Life Sci 1980;28:609–21.
  • Dial EW, Thompson WJ, Rosenfeld GC. Isolated parietal cells: histamine response and pharmacology. J Pharmacol Exp Ther 1981;219:585–90.
  • Roland M, Berstad A, Liavåg I. Effect of carbacholine and urecholine on pentagastrin-stimulated gastric secretion in healthy subjects. Scand J Gastroenterol 1975;10:357–62.
  • Svensson SE. The secretory pattern of three stomach preparations in the rat. J Physiol 1970;207:329–50.
  • Cleator DGM, Stoller JM, Johnstone BRC, Holubitsky IB, Harrison RC. Comparison between the effect of pentagastrin and histalog on gastric acid secretion. Am J Dig Dis 1972;17:713–9.
  • Bergegårdh S, Broman G, Knutson U, Palmer L, Olbe L. Gastric acid responses to graded i.v. infusion of pentagastrin and histalog in peptic ulcer patients before and after antrum-bulb resection. Scand J Gastroenterol 1976;11:337–46.
  • Larsson H, Carlsson E, Ryberg B, Fryklund J, Wallmark B. Rat parietal cell function after polonged inhibition of gastric acid secretion. Am J Physiol 1988;254:G33–9.
  • Lindstrøm E, Björkqvist M, Boketoft Å, Chen D, Zhao C-M, Kimura K, et al. Neurohormonal regulation of histamine and pancreastatin secretion from isolated rat stomach ECL cells. Gastroenterology 1997;112:A1167.
  • Blair AJ, Richardson CT, Walsh JH, Feldman M. Variable contribution of gastrin to gastric acid secretion after a meal in humans. Gastroenterology 1987;92:944–9.
  • Sandvik AK, Waldum HL. Rat gastric histamine release: a sensitive gastrin bioassay. Life Sci 1990;46:453–9.
  • Black JW, Duncan WaM, Durant CJ, Ganellin CR, Parsons EM. Definition and antagonism of histamine H2-receptors. Nature 1972;236: 385–90.
  • Petersen H, Grossman MI. Stimulation of gastric acid secretion by dimaprit in unanesthetized rats. Agents Actions 1978;8:566–7.
  • Parsons M, Sykes C. Impromidine (SK&F 92676) acts as a partial agonist on the isolated whole stomach of the rat. Br J Pharmacol 1980;69:6–7.
  • Trzeciakowski JP. Inhibition of guinea pig ileum contractions mediated by a class of histamine receptor resembling the H3 subtype. J Pharmacol Exp Ther 1987;243:874–80.
  • Kirsner JB, Ford H. The gastric secretory response to Histalog: one-hour basal and Histalog secretion in normal persons and in patients with duodenal ulcer and gastric ulcer. J Lab Clin Med 1955;46:307–11.
  • Aubrey DA. The effects on human gastric secretion of prolonged continuous intravenous infusions of maximal and supramaximal doses of histamine acid phosphate and pentagastrin. Gut 1970;11:392–4.
  • Pisegna JR, Norton JA, Slimak GG, Metz DC, Maton PN, Gardner JD, et al. Effect of curative gastrinoma resection on gastric secretory function and antisecretory drug requirement in the Zollinger-Ellison syndrome. Gastroenterology 1992;102:767–78.
  • Karam SM Cell dynamics in the body (corpus) of the mouse stomach [thesis]. Montreal: McGill University; 1990.
  • Tari A, Wu V, Sumii M, Sachs G, Walsh JH. Regulation of rat gastrin H+/K+-ATPase α-subunit mRNA by omeprazole. Biochim Biophys Acta 1991;1129:49–56.
  • Swarovsky B, Eissele R, Gross M, Körtner G, Koop H, Arnold R, et al. Expression of the gastric H+/K+-ATPase and histidine decarboxylase during omeprazole treatment. Digestion 1994; 55:97–102.
  • Brenna E, Swarts HGP, Klaassen CHW, de Pont JJHHM, Waldum HL. Evaluation of the trophic effect of longterm treatment with the histamine H2 receptor antagonist loxtidine on rat oxyntic mucosa by differential counting of dispersed cells. Gut 1994;35: 1547–50.
  • Emaas S, Svensson S-C, Dorner M, Kaess H. Gastric acid and serum gastrin responses to insulin and 2-deoxy-D-glucose in duodenal ulcer patients before and after partial gastrectomy. Scand J Gastroenterol 1976;11: 667–72.
  • Feldman M, Richardson CT, Fordtran JS. Effect of sham feeding on gastric acid secretion in healthy subjects and duodenal ulcer patients: evidence for increased basal vagal tone in some ulcer patients. Gastroenterology 1980;79:796–800.
  • Mayer G, Arnold R, Feurle G, Fuchs K, Ketterer H, Track NS, et al. Influence of feeding and sham feeding upon serum gastrin and gastric acid secretion in control subjects and duodenal ulcer patients. Scand J Gastroenterol 1974;9:703–10.
  • Fordtran JS, Walsh JH. Gastric acid secretion rate and buffer content of the stomach after eating. Results in normal subjects and in patients with duodenal ulcer. J Clin Invest 1973;52:645–57.
  • Malagelada JR, Longstreth GF, Summerskill WHJ, Go VLW. Measurement of gastric functions during digestion of ordinary solid meals in man. Gastroenterology 1976;70:203–10.
  • Mignon M, Vatier J, Ruskoné A, Merrouche M, Bonfils S. Gastric acid secretion in response to food. In: Young JA, editor. Gastrointestinal physiology. IV. Int Rev Physiol 1983;28:53–83.
  • Halter F, Keller M. A comparison between intragastric titration and aspiration technique under basal conditions and after food or pentagastrin stimulation. Dig Dis 1978;23:723–9.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.