Non-Polypoid Adenomas of the Colon Are Associated with Subjacent Lymphoid Nodules: An Experimental Study in Rats

References

• Hardman WE, Cameron IL. Colonic crypts located over lymphoid nodules of 1,2-dimethylhydrazine-treated rats are hyperplastic and at high risk of forming adenocarcinomas. Carcinogenesis 1994;15:2353–61.
   PubMedGoogle Scholar
• Shimamoto F, Vollmer E. Changes in intestinal mucosa above lymph follicles during carcinogenesis in rats. J Cancer Res Clin Oncol 1987;113:41–50.
   PubMedGoogle Scholar
• Carter JW, Lancaster HK, Hardman WE, Cameron IL. Distribution of intestine-associated lymphoid tissue, aberrant crypt foci, and tumors in the large bowel of 1,2-dimethulhydrazine-treated mice. Cancer Res 1994;54:4304–7.
   PubMed Web of Science ®Google Scholar
• Shamsuddin AM, Hogan ML. Large intestinal carcinogenesis. II. Histogenesis and unususl features of low-dose azoxymethane-induced carcinoma in F344 rats. J Natl Cancer Inst 1984;73:1297–305.
   Google Scholar
• Nauss KM, Locniskar M, Pavlina T, Newberne PM. Morphology and distribution of 1,2-dimethylhydrazine- dihydrochloride- induced colon tumors and their relationship to gut-associated lymphoid tissue in the rat. J Natl Cancer Inst 1984;73:915–24.
   PubMed Web of Science ®Google Scholar
• Martin MS, Hammann A, Martin F. Gut-associated lymphoid tissue and 1,2-dimethilhydrazine intestinal tumors in the rat: an histological and immunoenzymatic study. Int J Cancer 1986;38: 75–80.
   Google Scholar
• Cameron IL, Garza J, Hardman WE. Distribution of lymphoid nodules, aberrant crypt foci and tumours in the colon of carcinogen-treated rats. Br J Cancer 1996;73:893–8.
   Google Scholar
• Rubio CA. Lymphoid tissue-associated colonic adenocarcinomas in rats. In Vivo 1987;1:61–4.
   PubMedGoogle Scholar
• Rubio CA, Kumagai J, Kanamori T, Yanagisawa A, Nakamura K, Kato Y. Flat adenomas and flat adenocarcinomas of the colorectal mucosa in Japanese and Swedish patients. Dis Colon Rectum 1995;38:1075–9.
   PubMedGoogle Scholar
• Rubio CA, Kumagai J, Kanamor T, Nakamura K. Apoptosis in flat neoplasia of the colorectal mucosa. In Vivo 1995;9:173–6.
   PubMedGoogle Scholar
• Rubio CA, Shetye J. Flat adenoma-adenocarcinoma sequence on the colon of rats. Dis Colon Rectum 1994;37:1300–6.
   PubMedGoogle Scholar
• Wolber RA, Owen DA. Flat adenomas of the colon. Hum Pathol 1991;22:70–4.
   PubMed Web of Science ®Google Scholar
• Muto T, Kamiya J, Sawada T, Konishi F, Sugihara K, Kubota Y, et al. Small ‘flat adenoma’ of the large bowel with special reference to its clinicopathologic features. Dis Colon Rectum 1985;28:847–51.
   PubMed Web of Science ®Google Scholar
• Laqueur GL, Mickelson O, Whiting MG, Kurland L. Carcinogenesis of nuts from cycas circinalis I., indigenous to Guam. J Natl Cancer Inst 1963;31: 919–51.
   PubMed Web of Science ®Google Scholar
• Ward J. Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats. Lab Invest 1974;30:506–13.
   Google Scholar
• Maskens AP, Dujardin-Loits RM. Experimental adenomas and carcinomas of the large intestine behave as distinct entities. Cancer 1981;47:81–9.
   PubMedGoogle Scholar
• Pozharisski KM. Morphology and morphogenesis of experimental epithelial tumors of the intestine. J Natl Cancer Inst 1975;54:1115–35.
   PubMed Web of Science ®Google Scholar
• Carachi R, Busuttil A, Joffe SN, Blumgart LH. Multiple polyps and colonic neoplasia induced in the rat. J Surg Res 1980;29: 363–70.
   PubMedGoogle Scholar
• Madara JL, Harte P, Deasy J, Ross D, Lahey S, Steele G Jr. Evidence for an adenoma-carcinoma sequence in dimethylhydrazine-induced neoplasms in rat intestinal epithelium. Am J Pathol 1983;110:230–5.
   Google Scholar
• Rubio CA, Nylander G, Sveander M, Duvander A, Alun ML. Minimal invasive carcinoma of the colon of rats. Am J Pathol 1986;123:161–5.
   Google Scholar
• Jacobs LR. Alterations in surface ultrastructure and anionic sites of rat dimethulhydrazine-induced intestinal tumors. Virchows Arch B Cell Pathol 1981;37:207–16.
   Google Scholar
• Tamaru T, Kobayashi H, Kishimoto S, Kajiyama G, Shimamoto F, Brown WR. Histochemical study of colonic cancer in experimental colitis in rats. Dig Dis Sci 1993;38:529–37.
   PubMed Web of Science ®Google Scholar
• Rubio CA, Wallin B, Sveander M, Duvander A. A model for the study of metastases from colonic tumors by autotransplantation. Dis Colon Rectum 1987;30:884–7.
   PubMedGoogle Scholar
• Bansal BR, Mobini J, Bansal C. Multimodel immunotherapy of primary gastrintestinal tumors in rats. I. Histologic correlation. Cancer 1978;42:2070–96.
   Google Scholar
• Rubio CA, Wallin B, Ware J, Sveander M, Duvander A. Effect of indomethacin in autotransplanted colonic tumors. Dis Colon Rectum 1989;32:488–91.
   PubMedGoogle Scholar
• Rubio CA, Nylander G, Sveander M, Duvander A, Alun ML. Monitoring the histogenesis of colonic tumors in the Sprague-Dawley rat. J Surg Oncol 1986;31:225–8.
   PubMedGoogle Scholar
• Rubio CA, Kato Y, Hirota T, Muto T. Histologic classification of endoscopically removed flat colorectal polyps: a multicentric study. Jpn J Cancer Res 1996;87:849–55.
   PubMedGoogle Scholar
• Muto T, Bussey H, Morson BC. The evolution of cancer of the colon and rectum. Cancer 1975;36:2251–70.
   PubMed Web of Science ®Google Scholar
• Rubio CA, Takayama S. Difference in histology and size in colonic tumors of rats receiving two different carcinogens. J Environ Pathol 1994;13:191–7.
   PubMedGoogle Scholar
• Owen RL, Pierce NF, Cray WC Jr. Autoradiographic analysis of M cell uptake and transport of cholera vibrios into follicules of rabbit Peyer’s patches. Gastroenterology 1983;84:693–9.
   Google Scholar
• Kernels S, Bogdanova A, Colucci-Guyon E. Cytosolic distribution of villin in M cells from mouse Peyer’s patches correlates with the absence of a brush border. Gastroenterology 1996;110: 515–21.
   Google Scholar
• Park HS, Goodlad RA, Wright NA. The incidence of aberrant crypt foci and colonic carcinoma in dimethylhydrazine-treated rats varies in a site-specific manner and depends on tumor histology. Cancer Res 1997;57:4507–10.
   Google Scholar
• Rubio CA. Intraepithelial lymphocytes vs. colorectal neoplastic cells: who is winning the apoptotic battle? Minireview. Apoptosis 1997;2:489–93.
   Google Scholar
• Jacob E, Baker SJ, Swaminathan SP. ‘M’ cells in the follicule-associated epithelium of the human colon. Histopathology 1987; 11:941–52.
   Google Scholar
• Levine DS, Haggitt RC. Normal histology of the colon. Am J Surg Pathol 1989;13:966–84.
   PubMedGoogle Scholar
• Dukes C, Bussey HJR. The number of lymph follicles of the human large intestine. J Pathol 1926;29:111–6.
   Google Scholar
• Langman JM, Rowland R. The number and distribution of lymph follicles in the human large intestine. J Anat 1986;194: 189–94.
   Google Scholar
• Watanabe H, Margulis AR, Harter L. The occurrence of lymphoid nodules in the colon of adults. J Clin Gastroenterol 1983;5:535–9.
   PubMed Web of Science ®Google Scholar
• Rubio CA, Kato Y, Jonasson J. Non-polypoid adenomas of the stomach. APMIS. In press.
   Google Scholar
• Rubio CA. Differences in angiogenesis and collagenesis between exophytic and flat adenomas of the colorectal mucosa. Anticancer Res 1997;17:737–42.
   PubMedGoogle Scholar
• Olschwang S, Slezak P, Roze M, Jaramillo E, Nakano H, Koizumi K, et al. Somatically acquired genetic alterations in flat colorectal neoplasias. Int J Cancer 1998;77:366–9.
   PubMedGoogle Scholar