18
Views
7
CrossRef citations to date
0
Altmetric
Research Article

Voiding and the Sacral Reflex Arc: Lessons from Capsaicin Instillation

, &
Pages 46-50 | Published online: 09 Jul 2009

REFERENCES

  • Dixon J, Gilpin C. Presumptive sensory axons of the human urinary bladder. A fine ultrastructural study. J Anat 1987; 151: 199–207.
  • Wakabayashi Y, Tomoyoshi T, Fujimiya M, Arai R, Maeda T. Substance P-containing axon terminals in the mucosa of the human urinary bladder: pre-embedding immunohistochemistry using cryostat sections for elec-tron microscopy. Histochemistry 1993; 100: 401–7.
  • Gabella G, Davis C. Distribution of afferent axons in the bladders of rats. J Neurocytol 1998; 27: 141–55.
  • Morrison J. The activation of bladder wall afferent nerves. Exp Physiol 1999; 84: 131–6.
  • de Groat WC, Kawatani M, Hisamitsu T, Cheng CL, Ma CP, Thor K, et al. Mechanisms underlying the recovery of urinary bladder function following spinal cord injury. J Auton Nerv Syst 1990; 30: S71–7.
  • Blok BF, de Weerd H, Holstege G. Ultrastructural evidence for a paucity of projections from the lumbosa-cral cord to the pontine micturition center or M-region in the cat: a new concept for the organization of the micturition reflex with the periaqueductal gray as central relay. J Comp Neurol 1995; 359: 300–9.
  • Athwal BS, Berkley KJ, Hussain I, Brennan A, Craggs M, Sakakibara R, et al. Brain responses to changes in bladder volume and urge to void in healthy men. Brain 2001; 124: 369–77.
  • Caterina MJ, Rosen TA, Tominaga M, Brake AJ, Julius D. A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 1999; 398: 436–41.
  • Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997; 389: 816–24.
  • Fowler CJ, Jewkes D, McDonald WI, Lynn B, deGroat WC. Intravesical capsaicin for neurogenic bladder dysfunction (letter). Lancet 1992; 339: 1239.
  • Fowler CJ. Intravesical treatment of overactive bladder. Urology 2000; 55: 60–4.
  • Dasgupta P, Chandiramani VA, Beckett A, Fowler CJ, Crowe R, Shah PJRS. Flexible cystoscopic biopsies for evaluation of nerve densities in the suburothelium of the human urinary bladder. Br J Urol 1997; 80: 490–2.
  • Dasgupta P, Chandiramani VA, Beckett A, Scaravilli F, Fowler CJ. The effect of intravesical capsaicin on the suburothelial innervation in patients with detrusor hyper-reflexia. BJU Int 2000; 85: 238–45.
  • Fowler CJ, Beck RO, Gerrard S, Betts CD, Fowler CG. Intravesical capsaicin for treatment of detrusor hyperre-flexia. J Neurol Neurosurg Psychiatry 1994; 57: 169–73.
  • De Ridder D, Chandiramani V, Dasgupta P, Van Poppel H, Baert L, Fowler CJ. Intravesical capsaicin as a treatment for refractory detrusor hyperreflexia: a dual centre study with long-term followup. J Urol 1997; 158: 2087–92.
  • Avelino A, Cruz F. Peptide immunoreactivity and ultrastructure of rat urinary bladder nerve fibers after topical desensitization by capsaicin or resiniferatoxin. Auton Neurosci 2000; 86: 37–46.
  • Chandiramani VA, Petersen T, Duthie GS, Fowler CJ. Urodynamic changes during therapeutic intravesical instillations of capsaicin. Br J Urol 1996; 77: 792–7.
  • Dasgupta P, Fowler CJ, Stephen R. Electromotive drug administration (EMDA) of lidocaine to anesthetize the bladder before intravesical capsaicin. J Urol 1998; 159: 1857–61.
  • Lazzeri M, Beneforti P, Turini D. Urodynamic effects of intravesical resiniferatoxin in humans: preliminary results in stable and unstable detrusor. J Urol 1997; 158: 2093–6.
  • Cruz F, Guimaraes M, Silva C, Reis M. Suppression of bladder hyperreflexia by intravesical resiniferatoxin. Lancet 1997; 350: 640–1.
  • Silva C, Rio ME, Cruz F. Desensitization of bladder sensory fibers by intravesical resiniferatoxin, a capsaicin analog: long-term results for the treatment of detrusor hyperreflexia. Eur Urol 2000; 38: 444–52.
  • Yiangou Y, Facer P, Ford A, Brady C, Wiseman 0, Fowler CJ, et al. Capsaicin receptor VR1 and ATP-gated ion channel P2X3 in human urinary bladder. BJU Int 2001; 87: 774–9.
  • Avelino A, Cruz C, Nagy I, Cruz F. Vanilloid receptor 1 expression in the rat urinary tract. Neuroscience 2002; 109: 787–98.
  • Bumstock G, Dumsday B, Smythe A. Atropine resistant excitation of the urinary bladder: the possibility of transmission via nerves releasing a purine nucleotide. Br J Pharmacol 1972; 44: 451–61.
  • Ferguson D, Kennedy I, Buton T. ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes-a possible sensory mechanism? J Physiol 1997; 505: 503–11.
  • Elneil S, Skepper JN, Kidd EJ, Williamson JG, Ferguson DR. The distribution of P2X1 and P2X3 in the rat and human urinary bladder. Neurourol Urodyn 2000; 19: 462–3.
  • Birder LA, Kanai AJ, de Groat WC, Kiss S, Nealen ML, Burke NE, et al. Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells. Proc Natl Acad Sci USA 2001; Nov 6 98: 13396–401.
  • Wiseman OJ, Brady CM, Hussain IF, Watt H, Dasgupta P, Fowler CJ, et al. The ultrastructure of bladder lamina propria nerves in healthy subjects and in patients with detrusor hyperreflexia. J Urol 2002 (in press).
  • Hussain I, Fowler C, Landon D. Ultrastructural changes in the composition of lamina propria nerves following intravesical capsaicin therapy. Euro Urol 1999; 35 (Suppl 2): 95.
  • O'Reilly BA, Kosaka AH, Knight GF, Chang TK, Ford APDW, Rymer JM, et al. P2X receptors and their role in female idiopathic detrusor instability. J Urol 2002; 167: 157–64.
  • Andersson KE. Advances in the pharmacological control of the bladder. Exp Physiol 1999; 84: 195–213.
  • Sui GP, Rothery Y, Dupont E, Fry CH, Severs NJ. Gap junctions and connexin expression in human suburothe-lial interstitial cells. Br J Urol Int 2002; 90: 118–29.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.