87
Views
10
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

CHEK2*1100delC is not an important high-risk gene in families with hereditary prostate cancer in southern Sweden

, , , &
Pages 23-25 | Received 04 Apr 2005, Published online: 09 Jul 2009

References

  • Hsieh CL, Oakley-Girvan I, Balise RR, Halpern J, Gallagher RP, Wu AH, et al. A genome screen of families with multiple cases of prostate cancer: evidence of genetic heterogeneity. Am J Hum Genet 2001; 69: 148–58
  • Lichtenstein P, Holm NV, Verkasalo PK, Iliadou A, Kaprio J, Koskenvuo M, et al. Environmental and heritable factors in the causation of cancer—analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med 2000; 343: 78–85
  • Bratt O. Hereditary prostate cancer: clinical aspects. J Urol 2002; 168: 906–13
  • Easton DF, Schaid DJ, Whittemore AS, Isaacs WJ. Where are the prostate cancer genes? A summary of eight genome wide searches. Prostate 2003; 57: 261–9
  • Ross RK, Coetzee GA, Pearce CL, Reichardt JK, Bretsky P, Kolonel LN, et al. Androgen metabolism and prostate cancer: establishing a model of genetic susceptibility. Eur Urol 1999; 35: 355–61
  • Chaturvedi P, Eng WK, Zhu Y, Mattern MR, Mishra R, Hurle MR, et al. Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene 1999; 18: 4047–54
  • Chehab NH, Malikzay A, Appel M, Halazonetis TD. Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. Genes Dev 2000; 14: 278–88
  • Lee JS, Collins KM, Brown AL, Lee CH, Chung JH. hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response. Nature 2000; 404: 201–4
  • Meijers-Heijboer H, van den Ouweland A, Klijn J, Wasielewski M, de Snoo A, Oldenburg R, et al. Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nat Genet 2002; 31: 55–9
  • Schutte M, Seal S, Barfoot R, Meijers-Heijboer H, Wasielewski M, Evans DG, et al. Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility. Am J Hum Genet 2003; 72: 1023–8
  • Seppala EH, Ikonen T, Mononen N, Autio V, Rokman A, Matikainen MP, et al. CHEK2 variants associate with hereditary prostate cancer. Br J Cancer 2003; 89: 1966–70
  • Dong X, Wang L, Taniguchi K, Wang X, Cunningham JM, McDonnell SK, et al. Mutations in CHEK2 associated with prostate cancer risk. Am J Hum Genet 2003; 72: 270–80
  • Dufault MR, Betz B, Wappenschmidt B, Hofmann W, Bandick K, Golla A, et al. Limited relevance of the CHEK2 gene in hereditary breast cancer. Int J Cancer 2004; 110: 320–5
  • Consortium BCC-C. CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies. Am J Hum Genet 2004; 74: 1175–82
  • Cybulski C, Huzarski T, Gorski B, Masojc B, Mierzejewski M, Debniak T, et al. A novel founder CHEK2 mutation is associated with increased prostate cancer risk. Cancer Res 2004; 64: 2677–9

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.