References
- The compounds are commonly called ‘bis(guanylhydrazones)’. Therefore, their established abbreviations contain the letters GBG preceded by an indication of the substituents (e.g., DE for diethyl or EM for ethyl methyl). The term ‘bis-(amidinohydrazone)’ is, however, more appropriate. The Chemical Abstracts' systematic name of MGBG is 2,2′-(1-methyl-1,2-ethanediylidene)bis(hydrazinecarboximidamide), and other congeners are named analogously
- Freedlander , BL. and French , FA. 1958 . Carcinostatic Action of Polycarbonyl Compounds and Their Derivatives . Cancer Res. , 18 : 360
- Williams-Ashman , HG. and Schenone , A. 1972 . Methyl Glyoxal Bis(guanyl-hydrazone) as a Potent Inhibitor of Mammalian and Yeast S-Adenosylmethionine Decarboxylases . Biochem. Biophys. Res. Commun. , 46 : 288
- Seppänen , P. , Fagerström , R. , Alhonen-Hongisto , L. , Elo , H. , Lumme , P. and Jänne , J. 1984 . Glyoxal Bis(guanylhydrazone) as an Inhibitor of Polyamine Biosynthesis in Tumour Cells . Biochem. J. , 221 : 483
- Corti , A. , Dave , C. , Williams-Ashman , HG. , Mihich , E. and Schenone , A. 1974 . Specific Inhibition of the Enzymic Decarboxylation of S-Adenosylmethionine by Methylglyoxal Bis(guanylhydrazone) and Related Substances . Biochem. J. , 139 : 351
- Elo , H. , Mutikainen , I. , Alhonen-Hongisto , L. , Laine , R. , Jänne , J. and Lumme , P. 1986 . Biochemical Properties and Crystal Structure of Ethylmethylglyoxal Bis(guanylhydrazone) Sulfate - an Extremely Powerful Novel Inhibitor of Adenosylmethionine Decarboxylase . Z. Naturforsch., C , 41c : 851
- Elo , H. , Mutikainen , I. , Alhonen-Hongisto , L. , Laine , R. and Jänne , J. Manuscript submitted for publication
- Baiocchi , F. , Cheng , CC. , Haggerty , WJ. , Lewis , LR. , Liao , TK. , Nyberg , WH. , O'Brien , DE. and Podrebarac , EG. 1963 . Studies on Methylglyoxal Bis(guanylhydrazone) Analogs. II. Structural Variations on Methylglyoxal Bis(guanylhydrazone) . J. Med. Chem. , 6 : 431
- Podrebarac , EG. , Nyberg , WH. , French , FA. and Cheng , CC. 1963 . Studies on Methylglyoxal Bis(guanylhydrazone) Analogs. I. Homologs of Methylglyoxal Bis(guanylhydrazone) . J. Med. Chem. , 6 : 283
- Elo , H. Manuscript in preparation
- Alhonen-Hongisto , L. , Fagerström , R. , Laine , R. , Elo , H. and Jänne , J. 1984 . Different Efflux Rates May Determine the Cellular Accumulation of Various Bis(guanylhydrazones) . Biochem. J. , 221 : 273
- Seppänen , P. , Ruohola , H. and Jänne , J. 1984 . Ethylglyoxal Bis(guanylhydrazone) as an Inhibitor of Polyamine Biosynthesis in L1210 Leukemia Cells . Biochim. Biophys. Acta , 803 : 331
- Mutikainen , I. , Elo , H. and Lumme , P. 1986 . Crystal and Molecular Structure of Glyoxal Bis(amidinohydrazone) Dihydrochloride; Biochemical Aspects . J. Chem. Soc., Perkin Trans. II , : 291
- Elo , H. , Laine , R. , Alhonen-Hongisto , L. , Jänne , J. , Mutikainen , I. and Lumme , P. 1985 . Biochemical Characterization of Propylglyoxal Bis(guanylhydrazone). Facile Synthesis of Monoalkylglyoxal Bis(guanylhydrazones) . Z. Naturforsch., C , 40c : 839
- Thiele , J. and Dralle , E. 1898 . Zur Kenntniss des Amidoguanidins. I. Condensationsproducte des Amidoguanidins mit Aldehyden und Ketonen der Fettreihe . Liebig's Ann. Chem. , 302 : 275
- Jackmann , LM. and Sternhell , S. 1969 . Applications of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry , 2nd ed. , Vol. 191 , 226 – 227 . Oxford New York, Toronto, Sydney, Paris, Frankfurt : Pergamon Press .
- Ercoli , A. , Gardi , R. , Gladiali , S. , Tenconi , F. and Vitali , R. 1977 . Specific Synthesis of “Syn” and “Anti” Isomers of Testosterone Amidinohydrazone . Boll. Chim. Farm. , 116 : 218
- Shearer , CM. and DeAngelis , NJ. 1979 . Guanabenz Degradation Products and Stability Assay . J. Pharm. Sci. , 68 : 1010
- Szilágyi , L. , Györgydeák , Z. and Duddeck , H. 1986 . Aldose-Aminoguanidine Condensation Products: Syntheses and N. M. R. Studies . Carbohydr. Res. , 158 : 67
- Schulze , W. and Tresselt , D. 1986 . Strukturen der Monoguanylhydrazone substituierter 1,4-Benzochinone . Z. Chem. , 26 : 208
- Ceba , M. Roman , Nevado , JJ. Berzas and Mansilla , A. Espinosa . 1981 . Analytical Properties of Pyridine-2-aldehyde Guanylhydrazone . Talanta , 28 : 134
- Nevado , JJ. Berzas and Mansilla , A. Espinosa . 1984 . Valiente Gonzáles, P. Salicylaldehyde Guanylhydrazone as an Analytical Reagent for Spectrophotometric Estimation of Iron . Microchem. J. , 30 : 380
- Salinas , F. , Berzas , JJ. and Mansilla , A. Espinosa . 1985 . 2-Hydroxy-1-naphtaldehyde Guanylhydrazone as an Analytical Reagent. Extractive-Spectrophotometric Determination of Iron . Bull. Soc. Chim. Belg. , 94 : 719
- Hamilton , WC. and La Placa , SJ. 1968 . The Crystal and Molecular Structure of an Anti-Leukemia Drug: Methylglyoxal Bisguanylhydra-zone Dihydrochloride Monohydrate, C5N8H12.2HCl.H2O. Neutron and X-ray Diffraction Studies . Acta Cryst. , B24 : 1147
- Edmonds , JW. and Hamilton , WC. 1972 . The Crystal and Molecular Structure of Dimethylglyoxal Bisguanylhydrazone Dihydrochloride Dihydrate, C6H14N8.2HCl.2H2O . Acta Cryst. , B28 : 1362
- Lumme , PO. , Mutikainen , I. and Elo , HO. 1986 . Structure of Propylglyoxal Bis(amidinohydrazone) Sulfate Dihydrate . Acta Cryst. , C42 : 1209
- Mutikainen , I. , Elo , H. and Tilus , P. Manuscript submitted for publication