Publication Cover
Spectroscopy Letters
An International Journal for Rapid Communication
Volume 26, 1993 - Issue 8
5
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

Determination of the Stereochemistry of Substituted 5-Methylenehydantoins and Thiohydantoins by 13C NMR and Homonuclear NOE Experiments

, , &
Pages 1511-1521 | Received 16 Mar 1993, Accepted 10 May 1993, Published online: 23 Sep 2006

References

  • Kador , P. F. , Kinoshita , J. H. and Sharpless , N. E. 1985 . Aldose Reductase Inhibitors: A Potential New Class of Agents for the Pharmalogical Control of Certain Diabetic Complications. . J. Med. Chem. , 28 : 841 – 9 .
  • Lipinski , C. A. and Hutson , N. J. 1984 . Aldose Reductase Inhibitors as a new approach of the treatment of diabetic complications. . Annu. Rep. Med. Chem. , 19 : 169 – 77 . Chapter 17.
  • Mutschler , E. and Winterfeldt , E. Aldose Reductase Inhibitors. Trends in Medicinal Chemistry. VCH . 9th Symposium . 1986 , Berlin. pp. 551 – 564 .
  • Sarges , R. 1978 . G. pat. 2 , 821 : 966
  • U.S. pat. 4, 130, 714 . 1978 .
  • Tadao , T. , Masanori , K. , Akio , A. , Tetsuya , M. , Masaki , H. , Hiroshi , T. , Fumio , H. and Takeshi , M. 1982 . ONO Pharm. Co., Ltd, EP , 47 : 109
  • U.S. pat. 4, 464, 382 . 1984 .
  • 1987 . Epalrestat. Drugs in the Future . 12 (4) : 336 – 40 .
  • Wheeler , H. L. and Hoffmann , C. 1911 . On hydantoins: a synthesis of phenylalanine and of tyrosine. . Am. Chem. J. , 45 : 368 – 83 .
  • Ishida , T. , In , Y. , Inoue , M. , Ueno , Y. and Tanaka , C. 1989 . Structural Elucidation of Epalrestat (ONO-2235), A Potent Aldose Reductase Inhibitor, and isomerisation of its double bonds. . Tetrahedron Letters. , 3 (8) : 959 – 62 .
  • Tan , S. F. , Ang , K. P. and Fong , Y. F. 1986 . (Z)- and (E)-5-Aryl methylidene hydantoins: Spectroscopic Properties and Configuration Assignment. . J. Chem. Soc. Perkin Trans. II , : 1941 – 46 .
  • Vögeli , V. , Philipsborn , W. , Nagarajan , K. and Nair , M. D. 1978 . Structures of Addition Products of Acetylenedicarboxylic Acid Esters with Various Dinucleophiles. An Application of C,H-Spin-Coupling Constants. . Helv. Chim. Acta , 61 (2) : 607 – 17 . n°49

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.