References
- Griffin , R. J. , Curtin , N. J. , Newell , D. R. , Golding , B. T. , Durkacz , B. W. and Calvert , A. H. 1995 . The role of inhibitors of poly(ADP‐ribose) polymerase as resistance‐modifying agents in cancer chemotherapy . Biochemie , 77 : 408 – 422 .
- Dantzer , F. , Schreiber , V. , Niedergang , C. , Trucco , C. , Flatter , E. , De La Rubia , G. , Oliver , J. , Rolli , V. , Menissier de Murcia , J. and de Murrcia , G. 1999 . Involvement of poly(ADP‐ribose) polymerase in base excision repair . Biochemie , 81 : 69 – 75 .
- Kameshita , I. , Matsuda , Z. , Taniguchi , T. and Shizuta , Y. 1984 . Poly(ADP‐ribose) synthase: Separation and identification of three proteolytic fragments as the substrate binding domain, the DNA binding domain, and the automodification domain . J. Biol. Chem , 259 : 4770 – 4776 .
- Griffin , R. J. , Srinivasan , S. , White , A. W. , Bowman , K. , Calvert , A. H. , Curtin , N. J. , Newell , D. R. and Golding , B. T. 1996 . Novel benzimidazole and quinazolinone inhibitors of the DNA repair enzyme poly(ADP‐ribose) polymerase . Pharm. Sci. , 2 : 43 – 47 .
- White , A. W. , Almassy , T. , Calvert , A. H. , Crutin , N. J. , Griffin , R. J. , Hostomsky , Z. , Maegley , K. , Newell , D. R. , Srinivasan , S. and Golding , B. T. 2000 . Resistance‐modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of DNA repair enzyme poly(ADP‐ribose) polymerase . J. Med. Chem. , 43 : 4084 – 4097 .
- Phillips , M. A. 1928 . The formation of 2‐methyl benzimidazoles . J. Chem. Soc. , : 172 – 177 .
- Phillips , M. A. 1928 . The formation of 2‐substituted benzimidazoles . J. Chem. Soc. , : 2393 – 2399 .
- Griffin , R. J. , Calvert , A. H. , Curtin , N. J. , Newell , D. R. and Golding , B. T. Benzimidazole Compounds . US Patent 6,100,283 . Aug. 8, 2000 .
- Denny , W. A. , Rewcastle , G. W. and Baguley , B. C. 1990 . Potential antitumor agents. 59. Structure–activity relationships for 2‐phenylbenzimidazole‐4‐carboxamides, a new class of “minimal” DNA‐intercalating agents which may not act via topoisomerase II . J. Med. Chem. , 33 : 814