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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 37, 2007 - Issue 8
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Original Articles

Alkylation of 3‐Phenyl‐1H‐pyrazolo[4,3‐c] quinoline: Theoretical Analysis of Regioselectivity

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Pages 1321-1330 | Received 13 Jul 2006, Published online: 12 Apr 2007

References

  • Palazzino , G. , Cecchi , L. , Melani , F. , Colotta , V. , Filacchioni , G. , Martini , C. and Lucacchini , A. 1987 . 1,3‐Diarylpyrazolo[4,5‐c]‐and ‐[5,4‐c]quinolin‐4‐ones: Synthesis and specific inhibition of benzodiazepine receptor binding . J. Med. Chem. , 30 : 1737 – 42 .
  • Singh , P. , Ojha , T. N. and Sharma , R. C. 1990 . Quantitative structure–activity relationship study on some ligands acting as inhibitors of benzodiazepine‐receptor binding . Res. Commun. Chem. Pathol. Pharmacol , 67 : 151 – 4 .
  • Savini , L. , Chiasserini , L. , Pellerano , C. , Biggio , G. , Maciocco , E. , Serra , V. , Cinone , N. , Carrieri , A. , Altomare , C. A. and Carotti , A. 2001 . High affinity central benzodiazepine receptor ligands, part 2: Quantitative structure–activity relationships and comparative molecular field analysis of pyrazolo[4,3‐c]quinolin‐3‐ones . Bioorg. Med. Chem , 9 : 431 – 44 .
  • Skotnicki , J. , Gilman , S. C. , Steinbaugh , B. A. and Musser , J. H. US Patent 4748246 . 1988 .
  • Crespo , M. I. , Gracia , J. , Puig , C. , Vega , A. , Bou , J. , Beleta , J. , Domenech , T. , Ryder , H. , Segarra , V. and Palacios , J. M. 2000 . Synthesis and biological evaluation of 2,5‐dihydropyrazol . Bioorg. Med. Chem. Lett. , 10 : 2661 – 4 .
  • Wentland , M. P. US Patent 5334595 . 1994 . DerAbs. C94-248419
  • Suzuki , F. , Nakasato , Y. , Ohmori , K. , Tamura , T. , Hosoe , H. , Kubo , K. and Yoshitake , I. US Patent 5192768 . 1993 . Chem. Abstr. 1993 116(25) 255609m
  • Kinji , H. , Takahiro , T. , Makoto , I. , Toshiko , K. , Yukio , S. and Takuji , K. JP Patent 5132484 . 1993 .
  • Silin , O. V. , Savchenko , T. I. , Kovalenko , S. M. , Nikitchenko , V. M. and Ivachtchenko , A. V. 2004 . Synthesis of 5H‐Pyrazolo[4,3‐c]quinolines . Heterocycles , 63 : 1883 – 90 .
  • Baumer , V. N. , Silin , O. V. , Savchenko , T. I. , Nikitchenko , V. M. and Kovalenko , S. M. 2004 . 5‐Benzyl‐7,9‐dimethoxy‐3‐phenyl‐5H‐ pyrazolo[4,3‐c]quinolin‐1‐ium chloride acetic acid solvate . Acta Cryst. , E60 : 294 – 96 .
  • Dewar , M. J. S. , Zoebisch , E. G. , Healy , E. F. and Stewart , J. J. P. J. 1985 . A new general purpose quantum mechanical molecular model . Am. Chem. Soc. , 107 : 3902 – 9 .
  • Dewar , M. J. S. and Dieter , K. M. J. 1986 . Evaluation of AM1 calculated proton affinities and deprotonation enthalpies . Am. Chem. Soc. , 108 : 8075 – 86 .
  • Stewart , J. J. P. 1990 . MOPAC—A semiempirical molecular orbital program . J. Comp. Aided Mol. Design , 4 : 1
  • Izatt , R. M. , Pawlak , K. , Bradshaw , J. S. and Bruening , R. L. 1991 . Thermodynamic and kinetic data for macrocycle interactions with cations and anions . Chem. Rev. , 91 : 1721 – 2085 .
  • Furui , K. 1965 . Modern Quantum Chemistry, Istanbul Lectures , Part 1 Edited by: Sinanoglu , O. New York : Academic Press .
  • Ratcliffe , A. H. and Masek , B. B. WO Patent 94/03453 . 1994 .
  • Ife , R. G. , Brown , T. H. and Leach , C. A. 1988 . Chem. Abstr. , 109 : 073352v
  • Kalayanov , G. D. , Kang , S. K. , Cheon , H. G. , Lee , S. G. , Yum , E. K. , Kim , S. S. and Choi , J.‐K . 1998 . Synthesis of pyrazoloquinolines as gastric H+/K+‐ATPase inhibitors . Bull. Korean Chem. Soc. , 19 : 667 – 669 .

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