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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 38, 2008 - Issue 5
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Original Articles

Copper‐Catalyzed Coupling Reaction of 2‐Thioxo‐4‐quinazolinone and Thieno[3,2‐d]pyrimidin‐4‐one Methane Sulphonamide with Aryl Iodides: Preparation of Potential COX‐2 Selective Inhibitors

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Pages 723-737 | Received 15 Aug 2007, Published online: 15 Feb 2008

References

  • DeWitt , D. L. 1999 . Cox‐2‐selective inhibitors: the new super aspirins . Mol. Pharmacol. , 55 : 625 – 631 .
  • Dannhart , G. and Werner , K. 2001 . Cyclooxygenase inhibitors—Current status and future prospects . Eur. J. Med. Chem. , 36 : 109 – 126 .
  • Russo , F. , Santagati , M. , Santagati , A. , Amico‐Roxas , M. , Bitetti , R. and Russo , A. 1981 . Ricerche chimiche e farmacologiche su derivati del 5H‐1,3,4‐tia(oxa)diazolo[2,3‐b]chinazolin‐5‐one . Il Farmaco Ed. Sc. , 36 : 292 – 301 .
  • Russo , F. , Santagati , A. , Santagati , M. , Caruso , A. , Trombadore , S. and Amico‐Roxas , M. 1987 . Synthesis and pharmacological properties of benzothienothiadiazolopyrimidine derivatives . Il Farmaco Ed. Sc. , 42 : 437 – 447 .
  • Santagati , A. , Granata , G. , Marrazzo , A. and Santagati , M. 2003 . Synthesis and effects on the COX‐1 and COX‐2 activity in human blood ex vivo of derivatives containing the benzothieno[3,2‐a]pyrimidin‐4‐one heterocyclic system . Arch. Pharm. Pharm. Med. Chem. , 336 : 429 – 435 .
  • Granata , G. , Barbagallo , S. , Perdicaro , A. , Marrazzo , A. , Santagati , A. , Lombardo , L. and Cardile , V. 2006 . Synthetic approaches to bridghead nitrogen methanesulphonamide derivatives of 3‐amino‐2‐thioxo‐2,3‐dihydrothieno[2,3‐d]pyrimidin‐4(1H)‐ones, potential COX‐2 selective inhibitors . J. Heterocycles Chem. , 43 : 1099 – 1104 .
  • Wamhoff , W. 1985 . Advances in Heterocycles Chemistry: Heterocycles, β‐Enamino Esters, Versatile Synthons in Heterocyclic Synthesis Orlando, FL : Academic Press .
  • Gutschow , M. and Powers , J. 2001 . A new dimerization reaction producing 2‐amino‐9‐oxopyrrolo[2,1‐b]quinazoline‐1‐carbonitriles and analogous pyrrolo[1,2‐a]thieno[3,2‐d]pyrimidinecarbonitriles . J. Hetrocycl. Chem. , 38 : 419 – 424 .
  • Russo , F. , Santagati , M. and Santagati , A. 1979 . Sintesi e Reazioni di Alcuni 5H‐1,3,4‐tiadiazolo[2,3‐b]chinazolin‐5‐one‐2,7‐sostituiti . Il Farmaco Ed. Sc. , 34 : 688 – 697 .
  • Grafe , I. , Kottke , K. , Kuhmstedt , H. and Knoke , D. 1990 . Synthese von 3‐Hetaryl‐4‐oxo‐2‐thioxo‐und 3‐Hetaryl‐2,4‐dioxo‐1,2,3,4‐tetrahydrochinazolinen . Pharmazie , 45 : 530 – 531 .
  • Santagati , A. , Modica , M. , Monsù Scolaro , L. and Santagati , M. 1999 . New synthetic approaches to fused heterocycloquinazolines . J. Chem. Res., Miniprint , : 460 – 470 .

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