Acronycine Analog: New Selective Synthesis of 6‐Methoxy‐3,3‐dimethyl‐3H,7H‐pyrano[2,3‐c]xanthen‐7‐one

References

• Hughes , G. K. , Lahey , F. N. , Price , J. R. and Webb , L. J. 1948 . Alkaloids of the Australian Rutaceae . Nature , 162 : 233
   Google Scholar
• Svoboda , G. H. , Poore , G. A. , Simpson , P. J. and Boder , G. R. 1966 . Alkaloids of Acronycia baueri: Isolation of the alkaloids and study of the antitumor and other biological properties of acronycine . J. Pharm. Sci. , 55 : 758
   PubMed Web of Science ®Google Scholar
• Dorr , R. T. , Liddli , J. D. , Von Hoff , D. D. , Soble , M. and Osborne , C. K. 1966 . Antitumor activity and murine pharmacokinetics of parenteral acronycine . Cancer Res. , 55 : 758
   Google Scholar
• Reish , J. and Schiwek , K. 1994 . Acronycin‐epoxid and acronycin‐diol . Liebigs Ann. Chem. , : 317
   Google Scholar
• Elomri , A. , Koch , M. , Seguin , E. , Tillequin , F. , Pierre , A. and Atassi , G. 1999 . Synthesis and cytotoxic activity of 11‐nitro and 11‐amino derivatives of acronycine and 6‐demethoxy‐acronycine . Chem. Pharm. Bull. (Tokyo) , 47 : 1604 – 1606 .
   Google Scholar
• Svoboda , G. H. 1966 . Alkaloids of Acronycia baueri—Extraction of the alkaloids and studies of structure–activity relationships . Lloydia , 29 : 206
   Google Scholar
• Shieh , H. L. , Pezzuto , J. M. and Cordell , G. A. 1992 . Evaluation of the cytotoxic mechanisms mediated by the broad spectrum antitumor alkaloid acronycine and selected semisynthetic derivatives . Chem. Biol. Interact. , 81 : 35
   Google Scholar
• Elmori , A. , Michel , S. , Tillequin , F. and Koch , M. 1992 . A novel synthesis of 6‐demethoxyacronycine . Heterocycles , 34 : 799
   Google Scholar
• Schneider , J. , Evans , E. L. , Grunberg , E. and Fryer , R. I. 1972 . Synthesis and biological activity of acronycine analogs . J. Med. Chem. , 15 : 266
   Google Scholar
• Bongui , J.‐B. , Elmori , A. , Seguin , E. , Tillequin , F. , Pfeiffer , B. , Pierre , A. P. and Atassi , G. 2001 . Synthesis and cytotoxic activity of benzophenanthroline analogues of acronycine . Chem. Pharm. Bull. , 49 : 1077
   Google Scholar
• Kostakis , I. , Ghirtis , K. , Pouli , N. , Marakos , P. , Skaltsounis , A.‐L. , Leonce , S. , Caignard , D. H. and Atassi , G. 2000 . Synthesis and cytotoxic activity of 2‐dialkylaminoethylamino substituted xanthenone and thioxanthenone derivatives . Farmaco , 55 : 455
   Google Scholar
• Tillequin , F. 2002 . Conception de nouveaux agents antitumoraux en série acronycine . Ann. Pharm. Fr. , 60 : 246
   Google Scholar
• Ahluwalia , V. K. , Jolly , R. S. and Tehim , A. K. 1983 . A convenient synthesis of dihydropyrano‐xanthones . J. Chem. Soc., Perkin Trans. 1 , : 1229
   Google Scholar
• Ghirtis , K. , Pouli , N. , Marakos , P. , Skaltsounis , A.‐L. , Leonce , S. , Caignard , D. H. and Atassi , G. 2000 . Synthesis and conformational analysis of some new pyrano[2,3‐c]xanthen‐7‐one and new pyrano[2,3‐b]xanthen‐6‐one derivatives with cytotoxic activity . Heterocycles , 53 : 93
   Google Scholar
• Guyot , M. and Mentzer , C. 1965 . Sur une nouvelle méthode générale de synthèse de xanthones naturelles . Bull. Soc. Chim. Fr. , : 2558
   Google Scholar
• Kirkiacharian , B. S. 1981 . Condensations thermiques: Nouvelles synthèses de la tétrahydro‐5,6,7,8‐flavone et de l'octahydroxanthone . Comptes Rendus Acad. Sci. , 293 : 149 (série II)
   Google Scholar
• Johnson , A. P. and Pelter , A. 1966 . The structure of robustic acid, a new 4‐hydroxy‐3‐phenylcoumarin . J. Chem. Soc. C , : 610
   Google Scholar