Heterocyclic Synthesis with Nitriles: Synthesis of Pyrazolopyrimidine and Pyrazolopyridine Derivatives

REFERENCES

• Hamilton , H. W. ; Ortwine , D. F. ; Worth , D. F. ; Bristol , J. A. Synthesis and structure–activity relationships of pyrazolo[4,3-d]pyrimidin-7-ones as adenosine receptor antagonists . J. Med. Chem. 1987 , 30 , 91 – 96 .
   PubMedGoogle Scholar
• Poulsen , S. A. ; Quinn , R. J. Synthesis and structure–activity relationship of pyrazolo[3,4-d]pyrimidines: Potent and selective adenosine A1 receptor antagonists . J. Med. Chem. 1996 , 39 , 4156 – 4161 .
   PubMedGoogle Scholar
• Harden , F. A. ; Quinn , R. J. ; Scammells , P. J. Synthesis and adenosine receptor affinity of a series of pyrazolo[3,4-d]pyrimidine analogs of 1-methylisoguanosine . J. Med. Chem. 1991 , 34 , 2892 – 2898 .
   PubMedGoogle Scholar
• Lynck , B. M. ; Khan , M. A. ; Teo , H. C. ; Pedrotti , F. Pyrazolo[3,4-b]pyridines: Syntheses, reactions, and nuclear magnetic resonance spectra . Can. J. Chem. 1988 , 66 , 420 – 428 .
   Google Scholar
• Salaheldin , A. M. ; Campos , A. M. ; Rodrigues , L. M. N-Bromosuccinimide assisted oxidation of 5-aminopyrazoles: Formation of bis diazenylderivatives . Tetrahedron Lett. 2007 , 48 , 8819 – 8822 .
   Google Scholar
• Campos , A. M. ; Salaheldin , A. M. ; Rodrigues , L. M. Synthesis of some novel pyrazolo[3,4-d]pyrimidine derivatives . Arkivoc 2007 , 14 , 92 – 100 .
   Google Scholar
• Gupta , S. ; Rodrigues , L. M. ; Esteves , A. P. ; Oliveira-Campos , A. M. F. ; Nascimento , M. S. J. ; Nazareth , N. ; Cidade , H. ; Neves , M. P. ; Pinto , E. F. M. ; Cerqueira , N. M. F. ; Brás , N. Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors . Eur. J. Med. Chem. 2008 , 43 , 771 .
   PubMed Web of Science ®Google Scholar
• Taylor , E. D. ; Borror , A. L. The reaction of nitriles with o-aminonitriles: A convenient synthesis of fused 4-aminopyrimidine. J. Org. Chem. 1961, 26, 4967–4974.
   Google Scholar
• Smyrl , N. R. ; Smithwick , R. W. Hydroxide-catalyzed synthesis of heterocyclic aromatic amine derivative from nitriles . J. Heterocycl. Chem. 1982 , 19 , 493 – 496 .
   Web of Science ®Google Scholar
• Veronese , A. C. ; Callegari , R. ; Salah , S. A. Tin(VI) chloride-promoted reaction of β-dicarbonyl compounds with nitrile: Synthesis of aminopyridines and aminoquinolines . Tetrahedron. Lett. 1990 , 31 , 3485 – 3488 .
   Google Scholar
• Cheng , C. C. ; Robins , R. K. Potential purine antagonists, VI: Synthesis of 1-alkyl-and 1-aryl-4-substituted pyrazolo[3,4-d]pyrimidines . J. Org. Chem. 1956 , 21 , 1240 – 1256 .
   Web of Science ®Google Scholar