Synthesis of 1-Amino-6,7-dihydro-7-(hydroxymethyl)-4-nitro-pyrrolo[1,2-f]pyrimidin-3-(5H)-one from 2-Amino-6-methylpyrimidin-3-one

REFERENCES

• Wang , X. W. ; Lou , Q. H. ; Gou , Y. ; Xu , Y. ; Zhang , Z. L. ; Liu , J. Y. The design and synthesis of 9-phenylcyclohepta[d]pyrimidine-2,4-dione derivatives as potent non-nucleoside inhibitors of HIV reverse transcriptase . Org. Biomol. Chem. 2006 , 4 , 3252 – 3258 .
   Google Scholar
• Lu , X. ; Chen , Y. L. ; Guo , Y. ; Liu , Z. M. ; Shi , Y. W. ; Xu , Y. ; Wang , X. W. ; Zhang , Z. L. ; Liu , J. Y. The design and synthesis of N-1-alkylated-5-aminoaryalkyl-substituted-6-methluracils as potential non-nucleoside HIV-1 RT inhibitors . Bioorg. Med. Chem. 2007 , 15 , 7399 – 7407 .
   Google Scholar
• McMath , G. G. ; Aitken , D. J. ; Guillaume , D. ; Chiraroni , A. ; Riche , C. ; Husson , H. P. An unexpected synthesis of a dihydropyrrolo-[1,2-c]pyrimidinedione nucleoside analog from 5-fluorouracil . J. Chem. Res. (S) 1998 , 260 – 261 .
   Google Scholar
• Wang , X. W. ; Chen , Y. L. ; Guo , Y. ; Li , A. M. ; Ma , X. Y. ; Liu , J. Y. Synthesis of 1-(alkyl)-5-dimethylamino-6-phenethyluracils as potent non-nucleoside HIV-1 RT inhibitors . Synth. Commun. 2007 , 37 , 2421 – 2431 .
   Web of Science ®Google Scholar
• Wang , X. W. ; Zhang , Z. L. ; Liu , J. ; Ma , X. Y. ; Liu , J. Y. Study on HIV-1 RT inhibitor, I: Synthesis of 1,3-dibenzyl-6-(3,4-epoxybutyl)uracil . Chin. J. Org. Chem. 2004 , 24 , 1271 – 1273 (in Chinese).
   Google Scholar