Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 39, 2009 - Issue 14
209
Views
9
CrossRef citations to date
0
Altmetric
Original Articles

Synthesis and Crystal Structure of 7,8-Dihydroquinolino[2,3-a]acridine Derivatives

, , , , &
Pages 2492-2505 | Received 28 Sep 2008, Published online: 16 Jun 2009

REFERENCES

  • Tanner , D. Chiral aziridines—their synthesis and use in stereoselective transformations . Angew. Chem., Int. Ed. Engl. 1994 , 33 , 599 .
  • Boulanger , C. ; Giorgio , C. ; Vierling , P. Synthesis of acridine-nuclear localization signal (NLS) conjugates and evaluation of their impact on lipoplex and polyplex-based transfection . Eur. J. Med. Chem. 2005 , 40 ( 12 ), 1295 .
  • Moor , M. J. ; Schultes , C. M. ; Cuesta , J. ; Cuenca , F. ; Gunaratnam , M. ; Tanious , F. A. Trisubstituted acridines as G-quadruplex telomere targeting agents: Effects of extensions of the 3, 6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation . J. Med. Chem. 2006 , 49 ( 2 ), 582 .
  • Chiron , J. ; Galy , J. P. Reactivity of the acridine ring: One-pot regioselective single and double bromomethylation of acridine and some derivatives . Synthesis 2004 , 3 , 313 .
  • Tu , S. J. ; Wang , Q. ; Zhang , Y. ; Xu , J. N. ; Zhang , J. P. ; Zhu , X. T. ; Shi , F. J. An efficient one-pot synthesis of N-carboxymethylacridine-1,8-dione derivatives under microwave irradiation . Hererocycl. Chem. 2006 , 43 ( 6 ), 1647 .
  • Shutske , G. M. ; Pierrat , F. A. ; Kapples , K. J. ; Cornfeldt , M. L. ; Szewczak , M. R. ; Huger , F. P. ; Bores , G. M. ; Haroutunian , V. ; Davis , K. L. 9-Amino-1,2,3,4-tetrahydroacridin-1-ols: Synthesis and evaluation as potential Alzheimer's disease therapeutics . J. Med. Chem. 1989 , 32 , 1805 .
  • Rosini , M. ; Antonello , A. ; Cavalli , A. ; Bolognest , M. L. ; Minarint , A. ; Marucci , G. ; Leonardi , A. ; Melchiorre , C. Prazosin-related compounds: Effect of transforming the piperazinylquinazoline moiety into an aminomethyltetrahydroacridine system on the affinity for α 1-adrenoreceptors . J. Med. Chem. 2003 , 46 , 4895 .
  • Dzierzbicka , K. ; Kolodziejczyk , A. M. ; Wysocka-Skrzela , B. ; Mysliwski , A. ; Sosnowska , D. Synthesis and antitumor activity of conjugates of muramyldipeptide, normuramyldipeptide, and desmuramylpeptides with acridine/acridone derivatives. J. Med. Chem. 2001, 44, 3606.
  • Dzierzbicka , K. ; Kolodziejczyk , A. M. Synthesis and antitumor activity of conjugates of muramyldipeptide or normuramyldipeptide with hydroxyacridine/acridone derivatives . J. Med. Chem. 2003 , 46 , 183 .
  • Ravi , H. ; Padma , T. ; Mayur , C. Y. ; Gowdahalli , K. ; Kuntebommanahalli , N. T. ; Peter , J. H. ; Yerigeri , M. Anti-calmodulin acridone derivatives modulate vinblastine resistance in multidrug resistant (MDR) cancer cells . Eur. J. Med. Chem. 2004 , 39 , 161 .
  • Philippe , B. ; Johann , B. ; Thomas , G. ; Martin , T. Acridine and acridone derivatives, anticancer properties, and synthetic methods: Where are we now? Anti-Cancer Agents Med. Chem. 2007 , 7 ( 2 ), 139 .
  • Laurent , B. ; Brigitte , B. ; Marie-Paule , H. ; Amelie , L. ; Marie-Helene , D. C. ; Daniele , C. ; Alain , C. ; Olivier , R. ; Martine , D. Amino- and glycoconjugates of pyrido[4,3,2-kl]acridine: Synthesis, antitumor activity, and DNA binding . Bioorg. Med. Chem. 2006 , 14 ( 22 ), 7520 .
  • Wainwright , M. J. Acridine—a neglected antibacterial chromophore . Antimicrob. Chemother. 2001 , 47 ( 1 ), 1 .
  • Han , G.-F. ; Wang , J.-J. ; Jiang , G.-J. Synthesis of chroman4-ono[2,3-b]quinolinone derivative . Chin. J. Org. Chem. 2003 , 23 ( 9 ), 1004 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.