REFERENCES
- Manns , M. P. ; McHutchison , J. G. ; Gordon , S. C. ; Rustgi , V. K. ; Shiffman , M. ; Reindollar , R. ; Goodman , Z. D. ; Koury , K. ; Ling , M. ; Albrecht , J. K. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial . Lancet 2001 , 358 , 958 .
- (a) Patterson , J. ; Fernandez-Larsson , R. Molecular mechanisms of action of ribavirin . Rev. Infect. Dis. 1990 , 12 , 1139 ; (b) Maag , D. ; Castro , C. ; Hong , Z. ; Cameron , C. E. Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin . J. Biol. Chem. 2001 , 49 , 46094 ; (c) Crotty , S. ; Cameron , C. E. ; Andino , R. RNA virus error catastrophe: Direct molecular test by using ribavirin . Proc. Natl. Acad. Sci. USA 2001 , 98 , 6895 .
- Carroll , S. S. ; Tomassini , J. E. ; Bosserman , M. ; Getty , K. ; Stahlhut , M. W. ; Eldrup , A. B. ; Bhat , B. ; Hall , D. ; Simcoe , A. L. ; Lafemina , R. ; Rutkowski , C. A. ; Wolanski , B. ; Yang , Z. ; Migliaccio , G. ; De Francesco , R. ; Kuo , L. C. ; MacCoss , M. ; Olsen , D. B. Inhibition of hepatitis C virus RNA replication by 2′-modified nucleoside analogs . J. Biol. Chem. 2003 , 278 , 11979 .
- Eldrup , A. B. ; Allerson , C. R. ; Bennett , C. F. ; Bera , S. ; Bhat , B. ; Bosserman , M. R. ; Brooks , J. ; Burlein , C. ; Carroll , S. S. ; Cook , P. D. ; Getty , K. L. ; MacCoss , M. ; MacMasters , D. R. ; Olsen , D. B. ; Prakash , T. ; Prhavc , M. ; Song , Q. ; Tomassini , J. E. ; Xia , J. Structure–activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase. J. Med. Chem. 2004, 47, 2283.
- De Francesco , R. ; Tomei , L. ; Altamura , S. ; Summa , V. ; Migliaccio , G. Approaching a new era for hepatitis C virus therapy: Inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase . Antivir. Res. 2003 , 58 , 1 .
- Migliaccio , G. ; Tomassini , J. E. ; Carroll , S. S. ; Tomei , L. ; Altamura , S. ; Bhat , B. ; Bartholomew , L. ; Bosserman , M. R. ; Ceccacci , A. ; Colwell , L. F. ; Cortese , R. ; De Francesco , R. ; Eldrup , A. B. ; Getty , K. L. ; Hou , X. S. ; LaFemina , R. L. ; Ludmerer , S. W. ; MacCoss , M. ; McMasters , D. R. ; Stahlhut , M. W. ; Olsen , D. B. ; Hazuda , D. J. ; Flores , O. A. Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro . J. Biol. Chem. 2003 , 278 , 49164 .
- Julander , J. G. ; Furuta , Y. ; Shafer , K.; Sidwell R. W. Activity of T-1106 in a hamster model of yellow fever virus Infection . Antimicrob. Agents Chemother. 2007 , 51 , 1962 .
- Jordan , I. ; Briese , T. ; Fischer , N. ; Lau , J. Y.-N. ; Lipkin , W. I. Ribavirin inhibits West Nile virus replication and cytopathic effect in neutral cells . J. Infect. Dis. 2000 , 182 , 1214 .
- Seley , K. L. ; O'Daniel , P. I. ; Salim , S. Design and synthesis of a series of chlorinated 3-deazaadenine analogs . Nucleosides, Nucleotides Nucl. Acids 2003 , 22 , 2133 .
- Franchetti , P. ; Cappellacci , L. ; Marchetti , S. ; Trincavelli , L. ; Martini , C. ; Mazzoni , M. R. ; Lucacchini , A. ; Grifantini , M. 2′-C-Methyl analogs of selective adenosine receptor agonists: Synthesis and binding studies . J. Med. Chem. 1998 , 41 , 1708 .
- Zhang , N. ; Chen , H.-M. ; Koch , V. ; Schmitz , H. ; Liao , C.-L. ; Bretner , M. ; Bhadti , V. S. ; Fattom , A. I. ; Naso , R. B. ; Hosmane , R. S. ; Borowski , P. Ring-expanded (“fat”) nucleoside and nucleotide analogs exhibit potent in vitro activity against Flaviviridae NTPases/helicases, including those of the West Nile virus, hepatitis C virus, and Japanese encephalitis virus . J. Med. Chem. 2003 , 46 , 4149 .
- Talekar , R. R. ; Wightman , R. H. Synthesis of pyrrolo[2,3-d]pyrimidine and 1,2,3-triazole isonucleosides . Tetrahedron 1997 , 53 , 3831 .