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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2010 - Issue 21
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Original Articles

Heterocyclizations via POCl3-Based Multicomponent Reactions: A New Approach to One-Pot Synthesis of a New Spirosystem, 7-Methyl-5-[4-(aryl/heteryl)thiazol-2-yl]-5,6-diazaspiro[2,4]hept-6-en-4-ones

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Pages 3186-3195 | Received 21 Jul 2009, Published online: 04 Oct 2010

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  • Harode , R. ; Sharma , T. C. Synthesis of 2-(3-methylpyrazol-5-one-1-yl)-4-ylthiazoles . J. Indian Chem. Soc. 1989 , 66 , 282 – 284 .
  • Srimanth , K. ; Rajeswar Rao , V. ; Krishna , D. R. Synthesis and evaluation of anticancer activity of some imidazothiazolyl, imidazobenzothiazolyl, and dihydroimidazothiazolyl coumarins . Arzneim. Forsch. Drug Res. 2002 , 52 ( 5 ), 388 – 392 ; (b) Rajeswar Rao , V. ; Srimanth , V. A facile one-step synthesis of 3-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-thiazolyl]-2H-1-benzopyran-2-ones under solvent-free conditions . J. Chem. Res. 2002 , 5 , 420 – 421 ; (c) Rajeswar Rao , V. ; Vijaya Kumar , P. Facile one-pot synthesis of 3-{2-[5-hydroxy-4-(2-hydroxy-ethyl)-3-methyl-pyrazol-1-yl]-thiazol-4-yl}-chromen-2-ones via a three-component reaction . Synth. Commun. 2006 , 36 , 2157 – 2161 ; (d) Rajeswar Rao , V. ; Seethalakshmi , T. ; Vijaya Kumar , P. ; Kalianman , P. N-[4-(2-Oxo-2H-chromen-3-yl)-3-phenyl-3H-thiazol-2-ylidene]anilinium bromide methanol solvate . Acta Cryst. E 2006 , E62 , 3771 – 3773 ; (e) Rajeswar Rao , V. ; Guravaiah , N. A facile one-pot synthesis of 2-pyrazolyl-4-aryl-thiazoles in a three-component reaction . J. Chem. Res. 2008 , 4 , 195 .
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