Efficient Synthesis of Hydroxytyrosol from 3,4-Dihydroxybenzaldehyde

REFERENCES

• Aruoma , O. I. ; Kaur , H. ; Halliwell , B. Oxygen free radicals and human diseases . J. R. Soc. Health 1991 , 111 , 172 – 177
   PubMedGoogle Scholar
• Espin , J. C. ; Solar-Rivas , C. ; Wichers , H. J. Characterization of the total free radical scavenger capacity of vegetable oils and oil fractions using 2,2-diphenyl-1-picrylhydrazyl radical . J. Agric. Food Chem. 2000 , 48 , 648 – 656 .
   PubMed Web of Science ®Google Scholar
• Capasso , R. ; Evidente , A. ; Schivo , I. ; Orru , G. ; Marcialis , M. A. ; Cristinzo , G. Antibacterial polyphenols from olive oil mill waste waters. J. Appl. Bacteriol. 1995, 79, 393–398.
   PubMedGoogle Scholar
• Petroni , A. ; Blasevich , M. ; Salami , M. ; Papini , N. ; Montedoro , G. F. ; Galli , C. Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil . Thromb. Res. 1995 , 78 , 151 – 160 .
   PubMed Web of Science ®Google Scholar
• Rastrelli , L. ; Passi , S. ; Ippolito , F. ; Vacca , G. ; Simone , F. D. Rate of degradation of α-tocopherol, squalene, phenolics, and polyunsaturated fatty acids in olive oil during different storage conditions . J. Agric. Food Chem. 2002 , 50 , 5566 – 5570 .
   PubMed Web of Science ®Google Scholar
• Lucia , M. D. ; Panzella , L. ; Pezzella , A. ; Napolitano , A. ; Ischia , M. Oxidative chemistry of the natural antioxidant hydroxytyrosol: Hydrogen peroxide-dependent hydroxylation and hydroxyquinone/o-quinone coupling pathways . Tetrahedron 2006 , 62 , 1273 – 1278 .
   Web of Science ®Google Scholar
• Obied , K. H. ; Allen , S. M. ; Bedgood , R. D. ; Prenzler , D. P. ; Robards , K. ; Stochman , R. ; Bioactivity and analysis of biophenols recovered from olive mill waste . J. Agric. Food Chem. 2005 , 53 , 823 – 837 .
   PubMed Web of Science ®Google Scholar
• Schopf , C. ; Gottmann , G. ; Meisel , E. M. Uber β-(3,4-dioxyphenyl)-athylalkohol . Liebigs Ann. Chem. 1949 , 563 , 86 – 93 .
   Google Scholar
• Capasso , R. ; Evidente , A. ; Avolio , S. ; A highly convenient synthesis of hydroxytyrosol and its recovery from agricultural waste waters . J. Agric. Food Chem. 1999 , 47 , 1745 – 1748 .
   PubMed Web of Science ®Google Scholar
• Bovicelli , P. ; Antonioletti , R. ; Mancini , S. ; Causio , S. ; Borioni , G. ; Ammendola , S. ; Barontini , M. Expedient synthesis of hydroxytyrosol and its esters . Synth. Commun. 2007 , 37 , 4245 – 4252 .
   Web of Science ®Google Scholar
• Takahashi , K. ; Shibasaki , K. ; Ogura , K. ; Iida , H. Efficient method for a one-carbon homologation of aldehydes and benzophenone to carboxylic acids . J. Org. Chem. 1983 , 48 , 3566 – 3569 .
   Web of Science ®Google Scholar