Design and Synthesis of Some New Pyrazolo[1,5-a]pyrimidines, Pyrazolo[5,1-c]triazines, Pyrazolo[3,4-d]pyridazines, and Isoxazolo[3,4-d]pyridazines Containing the Pyrazole Moiety

REFERENCES

• Taylor , E. C. ; Hartke , K. S. The reaction of malononitrile with substituted hydrazines: New routes to 4-aminopyrazolo[3,4-d]pyridazines . J. Am. Chem. Soc. 1959 , 81 , 2456 – 2464 .
   Web of Science ®Google Scholar
• Ho , Y. W. Synthesis of some new azopyrazolo[1,5-a]pyrimidine-thieno[2,3-b]pyridine derivatives and their application as disperse dyes. Dyes Pigm. 2005, 64, 223–230.
   Web of Science ®Google Scholar
• Singh , S. P. ; Kumer , D. Reinvestigation of the reported synthesis of naphtho[2′,1′-4,5]thiazolo[2,3-c][1,2,4]triazepins . Heterocycles 1990 , 31 , 855 – 860 .
   Web of Science ®Google Scholar
• Langenscheid , K. ; Luduing , G. Substituted 5-amino-4-formylcarbamoylpyrazoles. German Patent 2508, 1975 ; Chem Abstr. 1976 , 85 , 78124 , Chem. Abstr. 1976, 84, 44041e .
   Google Scholar
• Anderson , E. L. ; Lasey , J. F. ; Greene , L. C. ; Lafferty , J. L. ; Reift , H. E. Synthesis and muscle relaxant properties of 3-amino-4-arylazopyrazoles . J. Med. Chem. 1964 , 7 , 259 – 268 .
   PubMed Web of Science ®Google Scholar
• Elkhawaga , A. M. ; Kama-El-Dean , A. M. ; Radwan , S. M. ; Ahmed , M. M. Synthesis of some imidazopyrazolopyrimidines, pyrazolopyrimidopyrimidines, and pyrazolpyrimidinothiazines . Bull. Korean. Chem. Soc. 2009 , 30 , 561 – 566 .
   Web of Science ®Google Scholar
• Mohanty , S. K. ; Sridhar , P. , Sundar , R. ; Mittra , A. S. Fungicidal activity & synthesis of 5-thiopyrazolones and compounds having α-pyrone attached to pyrazolin nucleus . Indian J. Chem. 1977 , 15B , 1146 – 1148 .
   Google Scholar
• Sternbach , L. M. The benzodiazepine story . Prog. Drug. Res. 1978 , 22 , 229 .
   PubMedGoogle Scholar
• Jaiswal , N. ; Jaiswal , R. ; Barhwal , J. ; Kishor , K. Synthesis & biological activity of some new 10-[(3,5-diaryl-2-pyrazolin-1-yl)acetyl]-phenothiazines . Indian J. Chem. 1981 , 20B , 252 (2456) .
   Google Scholar
• Henning , G. Pyrazoline azo dyes . Germain Patent 261698, 1977 ; Chem. Abstr. 1978, 88, 38948v .
   Google Scholar
• Jain , R. ; Shukla , A. J. Indian Chem. Soc. 1990 , 67 , 575 .
   Web of Science ®Google Scholar
• Skippe , H. E. ; Robins , R. K. ; Thomson , J. R. ; Ching , C. C. ; Brockman , R. W. ; Schable , F. M. Structure–activity relationships observed on screening a neoplasms series of pyrazolopyrimidines against experimental . Cancer Res. 1957 , 17 , 579 – 596 .
   PubMed Web of Science ®Google Scholar
• Skippe , H. E. ; Robins , R. K. ; Thomson , J. R. Inhibition of experimental neoplasms by 4-aminopyrazolo[3,4-d]pyrimidine . Proc. Soc. Exptl. Biol. Med. 1955 , 89 , 594 – 596 .
   PubMed Web of Science ®Google Scholar
• Tominaga , Y. ; Honkawa , Y. ; Hara , M. ; Hosomi , A. Synthesis of pyrazolo[3,4- d ]pyrimidine derivatives using ketene dithioacetals . J. Heterocycl. Chem. 1990 , 27 , 775 – 783 .
   Web of Science ®Google Scholar
• Moukha-chafiq , O. ; Taha , M. L. ; Lazrek , H. B. ; Vasseur , J.-J. ; Pannecouque , C. ; Witvrouw , M. ; De Clercq , E. Synthesis and biological activity of some 4-substituted 1-[1-(2,3-dihydroxy-1-propoxy)methyl-1,2,3-triazol-(4 and 5)-ylmethyl]-1H-pyrazolo[3,4-d]pyrimidines . Farmaco , 2002 , 57 , 27 – 32 ; Chem. Abstr. 2002, 137, 93724z .
   PubMedGoogle Scholar
• Lowe , P. A. Aromatic and heteroaromatic chemistry . In Heterocyclic Chemistry ; H. Suschitzky and O. Meth-Cohn (Eds.); Chemical Society : London , 1980 ; vol. 1 , pp. 119 – 139 .
   Google Scholar
• Metzger , J. V. Thiazols and their benzo derivatives . In Comprehensive Heterocyclic Chemistry ; A. R. Katritzky and C. W. Rees (Eds.); Pergamon Press : Oxford , UK , 1984 ; vol. 6 , p. 328 .
   Google Scholar
• Brown , H. D. 2-Pyronyl and 2-thiopyronyl benzazoles . U.S. Patent, 3,278,547, 1966 , Chem. Abstr. 1966 , 65 , 18593 .
   Google Scholar
• Singh , S. P. ; Segal , S. Synthesis and phototoxicity of some 2-(phenyl or 2- or 3-thienyl)-4-substituted thiazoles . Indian J. Chem. B 1988 , 27 , 941 .
   Google Scholar
• Usui , Y. ; Yamano , T. ; Fungicides , X. Antifungal activity of 3-aminothiazoline-2-thione and 4H-1,3,4-thidiazine derivatives . Yakugaku Zasshi 1969 , 89 , 099 ; Chem. Abstr. 1969, 71, 69601 .
   Web of Science ®Google Scholar
• Goursot , P. ; Westrum Jr. , E. F. Heat capacity and thermodynamic properties of benzothiazol from 5 to 320 K . J. Chem. Eng. Data 1969 , 14 , 1 .
   Web of Science ®Google Scholar
• Abdelhamid , A. O. ; Ismail , Z. H. ; Abdel-Gawad , S. M. ; Ghorab , M. M. ; Abdel-Aziem , A. Synthesis of some new thieno[2,3-b]pyridine, pyrimidino[4′,5:4,5]thieno[2,3-b]-pyridine, and 2,3-dihydro-1,3,4-thiadiazole . Phosphorus, Sulfur Silicon Relat. Elem. 2009 , 184 , 58 – 75 .
   Web of Science ®Google Scholar
• Abdelhamid , A. O. ; Afifi , M. A. Synthesis Of some new thiazoles and pyrazolo[1,5-a]pyrimidines containing antipyrine moiety . Synth. Commun. 2010 , 40 , 1539 – 1550 .
   Web of Science ®Google Scholar
• Abdelhamid , A. O. ; Abdelall , E. K. A. ; Zaki , Y. H. Reactions with hydrazonoyl halides 62: Synthesis of some new imidazo[1,2-a]pyrimidine, imidazo[1,2-a]pyridine, imdazo[1,2-b]pyrazole, and quanazoline derivatives. J. Heterocycl. Chem. 2010, 47, 477–482.
   Web of Science ®Google Scholar
• Abdelhamid , A. O. Convenient synthesis of some new pyrazolo[1,5-a]pyrimidine, pyridine, thieno[2,3-b]pyridine, and isoxazolo[3,4-d]pyridazine derivatives containing benzofuran moiety . J. Heterocycl. Chem. 2009 , 46 , 680 – 686 (2009) .
   Web of Science ®Google Scholar
• Abdelhamid , A. O. ; Abdelall , E. K. A. ; Abdel-Riheem , N. A. ; Ahmed , S. A. Synthesis and antimicrobial activity of some new 5-arylazothiazole, pyrazolo[1,5-a]pyrimidine, [1,2,4]triazolo[4,3-a]pyrimidine, and pyrimido[1,2-a]benzimidazole derivatives containing the thiazole moiety . Phosphorus, Sulfur Silicon Relat. Elem. 2010 , 185 , 709 – 718 .
   Web of Science ®Google Scholar
• Abdelall , E. K. A. : Mohamed , M. A. ; Abdelhamid , A. O. Reactions with hydrazonoyl halides 63: synthesis and anticancer activity of some new 1,3,4-thiadiazoles, 1,3,4-selenadiazoles, and 1,2,4-triazolo[4,3-a]pyrimidines . Phosphorus, Sulfur, Silicon Relat. Elem. 2010 , 185 , 1862 – 1874 .
   Web of Science ®Google Scholar
• Abdelhamid , A. O. ; Afifi , M. A. Utility of 4-formylantipyrine in heterocyclic synthesis . J. Adv. Chem. 2010 , 1 , 137 .
   Google Scholar
• Abdelhamid , A. O. ; Shokry , A. S. ; Tawfiek , S. M. A new approach for the synthesis of some pyrazolo[5,1-c]triazines and pyrazolo[1,5-a]pyrimidines containing naphtofuran moiety . J. Heterocycl Chem. 2012 , 49 , 116 .
   Web of Science ®Google Scholar