Unusual product from the acid-catalyzed one-pot, multicomponent reaction of thiocarbohydrazide, aldehydes, and phenacyl bromides

References

• (a) Domling, A. Chem. Rev. 2006, 106, 17–89; (b) Biggs-Houck, J. E.; Younai, A.; Shaw, J. T. Curr. Opin. Chem. Biol. 2010, 14, 371–382; (c) Ramón, D. J.; Yus, M. Angew. Chem., Int. Ed. 2005, 44, 1602–1634 (d) Ruijter, E.; Scheffelaar, R.; Orru, R. V. A. Angew. Chem. Int. Ed. 2011, 50, 6234–6246.
   PubMed Web of Science ®Google Scholar
• (a) Rollas, S.; Küçükgüzel, Ş. Molecules 2007, 12, 1910–1939; (b) Garima, V.; Akranth, M.; Mohammad, S.; Mymoona, A.; Rahmat, A. M.; Mumtaz, A. M. J. Pharm. Bioallied Sci. 2014, 6(2), 69–80.
   PubMed Web of Science ®Google Scholar
• (a) Gudzera, O.; Golub, A.; Bdzhola, V.; Volynets, G.; Lukashov, S.; Kovalenko, O.; Kriklivyi, I.; Yaremchuk, A.; Starosyla, S.; Yarmoluk, S.; Tukalo, M. Bioorg. Med. Chem. 2016, 24, 1023–1031; (b) Makam, P.; Kankanala, R.; Prakash, A.; Kannan, T. Eur. J. Med. Chem. 2013, 69, 564–576.
   PubMed Web of Science ®Google Scholar
• Rudrapal, M.; Satyanandam, R. S.; Swaroopini, T. S.; Lakshmi, T. N.; Jaha, S. K.; Zaheera, S. Med. Chem. Res. 2013, 22, 2840–2846.
   Web of Science ®Google Scholar
• Makam, P.; Thakur, P. K.; Kannan, T. Eur. J. Pharm. Sci. 2014, 52, 138–145.
   PubMed Web of Science ®Google Scholar
• (a) Chimenti, F.; Bizzarri, B.; Maccioni, E.; Secci, D.; Bolasco, A.; Fioravanti, R.; Chimenti, P.; Granese, A.; Carradori, S.; Rivanera, D.; Lilli, D.; Zicari, A.; Distinto, S. Bioorg. Med. Chem. Lett. 2007, 17, 4635–4640; (b) Carradori, S.; Secci, D.; Bolasco, A.; Rivanera, D.; Mari, E.; Zicari, A.; Lotti, L. V.; Bizzarri, B. Eur. J. Med. Chem. 2013, 65, 102–111.
   PubMed Web of Science ®Google Scholar
• Carradori, S.; Rotili, D.; De Monte, C.; Lenoci, A.; D’Ascenzio, M.; Rodriguez, V.; Filetici, P.; Miceli, M.; Nebbioso, A.; Altucci, L.; Secci, D.; Mai, A. Eur. J. Med. Chem. 2014, 80, 569–578.
   PubMed Web of Science ®Google Scholar
• Gali, R.; Banothu, J.; Gondru, R.; Bavantula, R.; Velivela, Y.; Crooks, P. Bioorg. Med. Chem. Lett. 2015, 25, 106–112.
   PubMed Web of Science ®Google Scholar
• (a) D’Ascenzio, M.; Chimenti, P.; Gidaro, M. C.; De Monte, C.; De Vita, D.; Granese, A.; Scipione, L.; Di Santo, R.; Costa, G.; Alcaro, S.; Yanez, M.; Carradori, S. Enzyme Inhib. Med. Chem. 2015, 30(6), 908–919; (b) Chimenti, F.; Bizzarri, B.; Bolasco, A.; Secci, D.; Chimenti, P.; Carradori, S.; Granese, A.; Rivanera, D.; Frishberg, N.; Bordòn, C.; Jones-Brando, L. J. Med. Chem. 2009, 52, 4574–4577.
   PubMed Web of Science ®Google Scholar
• Makam, P.; Kankanala, R.; Prakash, A.; Kannan, T. Eur. J. Med. Chem. 2013, 69, 564–576.
   PubMed Web of Science ®Google Scholar
• Ozadali, K.; Unsal Tan, O.; Yogeeswari, P.; Dharmarajan, S.; Balkan, A. Bioorg. Med. Chem. Lett. 2014, 24, 1695–1697.
   PubMed Web of Science ®Google Scholar
• (a) Ali, T. J. Sulfur Chem. 2009, 30, 611–647; (b) Aly, A.; Brown, A.; El-Emary, T.; Mohamed Ewas, A.; Ramadan, M. Arkivoc 2009, 2009(i), 150–197.
   Web of Science ®Google Scholar
• Tashtoush, H.; Abusahyon, F.; Shkoor, M.; Al-Talib, M. J. Sulfur Chem. 2011, 32(5), 405–412.
   Web of Science ®Google Scholar
• Abdel-Aziem, A. J. Heterocyclic Chem. 2015, 52, 251–259.
   Web of Science ®Google Scholar
• (a) Xiabing, M.; Keyume, A.; Mamateli, O.; Mengnisa, S.; Reyhangul, R.; Wenbo, L. Tetrahedron 2016, 72, 2349–2353; (b) Zhang, D. N.; Li, J. T.; Song, Y. L.; Liu, H. M.; Li, H. Y. Ultrason. Sonochem. 2012, 19, 475–478; (c) Ding, Q.; Zhu, D.; Jin, H.; Chen, J.; Ding, J.; Wu, H. Phosphorus Sulfur Silicon Relat. Elem. 2011, 186, 220–224.
   Web of Science ®Google Scholar
• (a) Chunduru, V. S. R.; Vedula, R. R. Synth. Commun. 2012, 42, 1454–1460; (b) Penta, S.; Vedula, R. R. J. Sulfur Chem. 2011, 32(4), 327–333.
   Web of Science ®Google Scholar
• (a) Aychiluhim, T. B.; Vedula, R. R. Heterocycl. Commun. 2014, 20(4), 239–242; (b) Ramagiri, R. K.; Vaarla, K.; Vedula, R. R. Synth. Commun. 2016, 46(18), 1499–1506; (c) Pavurala, S.; Vaarla, K.; Vedula, R. R. J. Heterocyclic Chem. 2015, 52, 1503–1505; (d) Pavurala, S.; Vaarla, K.; Vedula, R. R. Phosphorus Sulfur Silicon Relat. Elem. 2017, 192(1), 69–72.
   Web of Science ®Google Scholar
• (a) Khafagy, M. M.; El-Maghraby, A. A.; Hassan, S. M.; Bashandy, M. S. Phosphorus Sulfur Silicon Relat. Elem. 2004, 179, 2113–2129; (b) Dabholkar, V. V.; Bhusari, N. V. J. Heterocyclic Chem. 2013, 50, 155–158.
   Web of Science ®Google Scholar