References
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- For synthesis of AV-45 from TEG-substituted 4-(N-methyl-N-Boc-amino)styrylpyridine (5), please see: (a) Hayashi, K.; Tachibana, A.; Tazawa, S.; Mizukawa, Y.; Osaki, K.; Morimoto, Y.; Zochi, R.; Kurahashi, M.; Aki, H.; Takahashi, K. J. Labelled Compd. Radiopharm. 2013, 56, 295–300. For other methods for synthesis of AV-45, please see: 1f and (b) Benedum, T.; Golding, G.; Lim, N.; Zhang, W. US Patent 2010/172836 A1, 2010; (c) Lee, S. J.; Oh, S. J.; Moon, D. H.; Ryu, J. S.; Kim, J. S.; Lee, J. J. EP Patent 2810926 A1, 2014; (d) Piramal, I. S. A; Berndt, M.; Friebe, M.; Samson, F.; Braun, R.; Garke, G.; Patt, M.; Schiddan, A.; Smuda, C. JP Patent 2016/47831 A1, 2016.
- Li, Z.; Liu, B.; Duan, W.; Zhu, L. Syn. Commun. 2015, 45, 2740–2747.
- For some reviews, see: (a) Maercker, A. Org. React. 1965, 14, 270–490 (b) Carruthers, W. Some Modern Methods of Organic Synthesis; Cambridge University Press: Cambridge, UK, 1971; pp 81–90; (c) Hoffmann, R. W. Angew. Chem. Int. Ed. 2001, 40, 1411–1416.
- Abu, T. K.; Lokman, H. C.; Subrata, G. Tetrahedron Lett. 2004, 45, 7891–7894.