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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 50, 2020 - Issue 7
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SYNTHETIC COMMUNICATIONS REVIEWS

Recent advances in development of anthelmintic agents: Synthesis and biological screening

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Pages 917-946 | Received 26 Aug 2019, Published online: 09 Mar 2020

References

  • Hosseinzadeh, Z.; Ramazani, A.; Razzaghi-Asl, N. Anti-Cancer Nitrogen-Containing Heterocyclic Compounds. Curr Org Chem. 2018, 22, 2256. DOI: 10.2174/1385272822666181008142138.
  • Jalili-Baleh, L.; Babaei, E.; Abdpour, S.; Bukhari, S. N. A.; Foroumadi, A.; Ramazani, A.; Sharifzadeh, M.; Abdollahi, M.; Khoobi, M. A Review on Flavonoid-Based Scaffolds as Multi-Target-Directed Ligands (MTDLs) for Alzheimer's Disease. Eur. J. Med. Chem. 2018, 152, 570. DOI: 10.1016/j.ejmech.2018.05.004.
  • Hosseinzadeh, Z.; Ramazani, A. An Overview of the Chemistry and Pharmacological Potentials of Furanones Skeletons. Curr Org Chem. 2019, 23, 1581. DOI: 10.2174/1385272823666190820111928.
  • Ahankar, H.; Ramazani, A.; Fattahi, N.; Ślepokura, K.; Lis, T.; Asiabi, P. A.; Kinzhybalo, V.; Hanifehpour, Y.; Joo, S. W. J. Chem. Sci. 2018, 130, 166. DOI: 10.1007/s12039-018-1572-7.
  • Hosseinzadeh, Z.; Ramazani, A.; Hosseinzadeh, K.; Razzaghi-Asl, N.; Gouranlou, F. An Overview on Chemistry and Biological Importance of Pyrrolidinone. Curr Org Synth. 2018, 15, 166. DOI: 10.2174/1570179414666170908165445.
  • Gupta, S.; Lakshman, M. J. Mahatma Gandhi Inst. Med. Sci. 2019, 2, 51. DOI: 10.4103/jmgims.jmgims_45_18.
  • Aghahosseini, H.; Ramazani, A.; Ślepokura, K.; Lis, T. The First protection-free synthesis of magnetic bifunctional l-proline as a highly active and versatile artificial enzyme: Synthesis of imidazole derivatives. J. Colloid. Interface Sci. 2018, 511, 222. DOI: 10.1016/j.jcis.2017.10.020.
  • Vekariya, R. H.; Patel, K. D.; Vekariya, M. K.; Prajapati, N. P.; Rajani, D. P.; Rajani, S. D.; Patel, H. D. Microwave-Assisted Green Synthesis of New Imidazo[2,1-b]Thiazole Derivatives and Their Antimicrobial, Antimalarial, and Antitubercular Activities. Res. Chem. Intermed. 2017, 43, 6207. DOI: 10.1007/s11164-017-2985-5.
  • Hosseinzadeh, Z.; Ramazani, A.; Razzaghi-Asl, N.; Slepokura, K.; Lis, T. Boric Acid as an Efficient and Green Catalyst for the Synthesis of2-Amino-4,6-Diarylnicotinonitrile under Microwave Irradiation in Solvent-Freeconditions. Turk. J. Chem. 2019, 43, 464. DOI: 10.3906/kim-1807-101.
  • Hosseinzadeh, Z.; Ramazani, A.; Ahankar, H.; Ślepokura, K.; Lis, T. Synthesis of 2-Amino-4,6-Diarylnicotinonitrile in the Presence of CoFe2O4@SiO2-SO3H as a Reusable Solid Acid Nanocatalyst under Microwave Irradiation in Solvent-Freeconditions. Silicon. 2019, 11, 2169. DOI: 10.1007/s12633-018-0034-7.
  • Sajjadifar, S.; Pal, K.; Jabbari, H.; Pouralimardan, O.; Divsar, F.; Mohammadi-Aghdam, S.; Amini, I.; Hamidi, H. Asain. J. Green Chem. 2019, 3, 226. DOI: 10.22631/ajgc.2017.46496.
  • Aghahosseini, H.; Ramazani, A.; Jalayer, N. S.; Ranjdoost, Z.; Souldozi, A.; Ślepokura, K.; Lis, T. Vinylphosphonium Salt-Mediated Reactions: A One-Pot Condensation Approach for the Highly cis -Selective Synthesis of N -Benzoylaziridines and the Green Synthesis of 1,4,2-Dioxazoles as Two Important Classes of Heterocyclic Compounds. Org. Lett. 2019, 21, 22. DOI: 10.1021/acs.orglett.8b03388.
  • Arzehgar, Z.; Sajjadifar, S.; Fekri, M. H. Chem. Methodol. 2019, 3, 251.
  • Ahankar, H.; Ramazani, A.; Slepokura, K.; Lis, T.; Joo, S. W. Turk. J. Chem. 2018, 42, 719.
  • Ramazani, A.; Khoobi, M.; Torkaman, A.; Zeinali Nasrabadi, F.; Forootanfar, H.; Shakibaie, M.; Jafari, M.; Ameri, A.; Emami, S.; Faramarzi, M. A.; et al. One-Pot, Four-Component Synthesis of Novel Cytotoxic Agents 1-(5-Aryl-1,3,4-Oxadiazol-2-yl)-1-(1H-Pyrrol-2-yl)Methanamines. Eur. J. Med. Chem. 2014, 78, 151. DOI: 10.1016/j.ejmech.2014.03.049.
  • Ahankar, H.; Ramazani, A.; Ślepokura, K.; Lis, T.; Kinzhybalo, V. Magnetic Cobalt Ferrite Nanoparticles Functionalized with Citric Acid as a Green Nanocatalyst for One-Pot Three-Component Sonochemical Synthesis of Substituted 3-Pyrrolin-2-Ones. Res. Chem. Intermed. 2019, 45, 5007. DOI: 10.1007/s11164-019-03878-1.
  • Hosseini, F.; Ramazani, A.; Mohammadi-Khanaposhtani, M.; Tehrani, M. B.; Nadri, H.; Larijani, B.; Mahdavi, M. Design, Synthesis, and Biological Evaluation of Novel 4-oxobenzo[d]1,2,3-triazin-benzylpyridinum derivatives as potent anti-Alzheimer agents. Bioorg. Med. Chem. 2019, 27, 2914. DOI: 10.1016/j.bmc.2019.05.023.
  • Yavari, I.; Ramazani, A. J. Chem. Res. 1996, 8, 382. DOI: 10.1039/a608156h.
  • Motamedi, R.; Ebrahimi, F.; Rezanejade Bardajee, G. Asian J. Green Chem. 2019, 3, 22.
  • Taran, J.; Ramazani, A.; Atrak, K. Iran. Chem. Commun. 2020, 8, 96.
  • Rouhani, M.; Ramazani, A. Perlite–SO3H Nanoparticles: Very Efficient and Reusable Catalyst for Three-Component Synthesis of N-Cyclohexyl-3-Aryl-Quinoxaline-2-Amine Derivatives under Ultrasound Irradiation. J. Iran. Chem. Soc. 2018, 15, 2375. DOI: 10.1007/s13738-018-1426-8.
  • Prajapati, S. M.; Patel, K. D.; Vekariya, R. H.; Panchal, S. N.; Patel, H. D. Recent Advances in the Synthesis of Quinolines: A Review. RSC Adv. 2014, 4, 24463. DOI: 10.1039/C4RA01814A.
  • Taghavi Fardood, S.; Ramazani, A.; Moradnia, F.; Afshari, Z.; Ganjkhanlu, S.; Yekke Zare, F. Chem. Methodol. 2019, 3, 696.
  • Taghavi Fardood, S.; Ramazani, A.; Ayubi, M.; Moradnia, F.; Abdpour, S.; Forootan, R. Chem. Methodol. 2019, 3, 583.
  • Ashtary, M.; Ramazani, A.; Rouhani, M. Iran. Chem. Commun. 2019, 7, 117.
  • Moradi, A.; Faraji, L.; Nadri, H.; Hasanpour, Z.; Moghadam, F. H.; Pakseresht, B.; Golshani, M.; Moghimi, S.; Ramazani, A.; Firoozpour, L.; et al. Synthesis, Docking Study, and Biological Evaluation of Novel Umbellipherone/Hymecromone Derivatives as Acetylcholinesterase/Butyrylcholinesterase Inhibitors. Med. Chem. Res. 2018, 27, 1741. DOI: 10.1007/s00044-018-2187-8.
  • Vekariya, R. H.; Patel, K. D.; Rajani, D. P.; Rajani, S. D.; Patel, H. D. J. Assoc. Arab Univ. Basic Appl. Sci. 2017, 23, 10. DOI: 10.1016/j.jaubas.2016.04.002.
  • Vekariya, R. H., Recent Advances in the Synthesis of Coumarin Derivatives via Knoevenagel Condensation: A Review. Synth. Commun. 2014, 44, 2756. DOI: 10.1080/00397911.2014.926374.
  • Vekariya, M. K.; Vekariya, R. H.; Patel, K. D.; Raval, N. P.; Shah, P. U.; Rajani, D. P.; Shah, N. K. Pyrimidine-Pyrazole Hybrids as Morpholinopyrimidine-Based Pyrazole Carboxamides: Synthesis, Characterisation, Docking, ADMET Study and Biological Evaluation. ChemistrySelect. 2018, 3, 6998. DOI: 10.1002/slct.201801011.
  • Vekariya, R. H.; Patel, K. D.; Patel, H. D. Fruit Juice of Citrus Limon as a Biodegradable and Reusable Catalyst for Facile, Eco-Friendly and Green Synthesis of 3,4-Disubstituted Isoxazol-5(4H)-Ones and Dihydropyrano[2,3-c]-Pyrazole Derivatives. Res. Chem. Intermed. 2016, 42, 7559. DOI: 10.1007/s11164-016-2553-4.
  • Gibson, D.; Harris, E.; Bray, R.; Jepson, P.; Kuiken, T.; Baker, J.; Simpson, V. A Survey of the Helminth Parasites of Cetaceans Stranded on the Coast of England and Wales during the Period 1990-1994. J. Zoology. 1998, 244, 563. DOI: 10.1017/S0952836998004099.
  • Sheth, U. Mechanisms of Anthelmintic Action. In Progress in Drug Research. Basel: Birkhäuser, 1975; pp 147–157.
  • Hall, A.; Hewitt, G.; Tuffrey, V.; De Silva, N. A Review and Meta-Analysis of the Impact of Intestinal Worms on Child Growth and Nutrition. Matern. Child Nutr. 2008, 4, 118. DOI: 10.1111/j.1740-8709.2007.00127.x.
  • de Silva, N.; Guyatt, H.; Bundy, D. Anthelmintics. Drugs 1997, 53, 769. DOI: 10.2165/00003495-199753050-00004.
  • Nanivadekar, A. S.; Gadgil, S. D.; Apte, V. V. Efficacy of Levamisole, Mebendazole, Piperazine and Pyrantel in Roundworm Infection. By National Anthelmintic Study Group. J. Postgrad. Med. 1984, 30, 144.
  • Mjos, K. P. In Kirk-Othmer Encyclopedia of Chemical Technology, 2nd ed.; Standen, A., Ed.; New York: Interscience, 1964; Vol. 15, pp. 638.
  • Cesbron, J. Y.; Capron, A.; Vargaftig, B. B.; Lagarde, M.; Pincemail, J.; Braquet, P.; Taelman, H.; Joseph, M. Platelets Mediate the Action of Diethylcarbamazine on Microfilariae. Nature 1987, 325, 533. DOI: 10.1038/325533a0.
  • MacKenzie, C. D.; Kron, M. A. Trop. Dis. Bull. 1985, 82, R1.
  • Mitchell, S. C. Phenothiazine: The Parent Molecule. CDT. 2006, 7, 1181. DOI: 10.2174/138945006778226552.
  • Ohlow, M. J.; Moosmann, B. Phenothiazine: The Seven Lives of Pharmacology's First Lead Structure. Drug Discov. Today. 2011, 16, 119. DOI: 10.1016/j.drudis.2011.01.001.
  • Robinson, H. J.; Silber, R. H.; Graessle, O. E. Tex. Rep. Biol. Med. 1969, 27, 537.
  • Pronk, M. E. J.; Schefferlie, G. J. WHO Food Addit. Ser. 2002, 49, 11.
  • Venkatesan, P. Albendazole. J. Antimicrob. Chemother. 1998, 41, 145. DOI: 10.1093/jac/41.2.145.
  • Critchley, J.; Addiss, D.; Ejere, H.; Gamble, C.; Garner, P.; Gelband, H. Albendazole for the Control and Elimination of Lymphatic Filariasis: Systematic Review. Trop. Med. Int. Health. 2005, 10, 818. DOI: 10.1111/j.1365-3156.2005.01458.x.
  • Villar, D.; Cray, C.; Zaias, J.; Altman, N. H. Biologic Effects of Fenbendazole in Rats and Mice: A Review. J. Am. Assoc. Lab. Anim. Sci. 2007, 46, 8.
  • Booze, T. F.; Oehme, F. W. A Literature Review of the Anthelmintic, Fenbendazole. Vet. Hum. Toxicol. 1982, 24, 49.
  • Al-Badr, A. A.; Tariq, M. Anal. Profiles Drug Subst. 1987, 16, 291. DOI: 10.1016/S0099-5428(08)60559-6.
  • Van den Bossche, H.; Rochette, F.; Hörig, C. Mebendazole and Related anthelmintics. Adv. Pharmacol. Chemother. 1982, 19, 67. DOI: 10.1016/s1054-3589(08)60021-6.
  • Bogan, J. A. Drugs Today. 1980, 16, 306.
  • Fairweather, I. Triclabendazole Progress Report, 2005–2009: An Advancement of Learning? J. Helminthol. 2009, 83, 139. DOI: 10.1017/S0022149X09321173.
  • Keiser, J.; Engels, D.; Büscher, G.; Utzinger, J. Triclabendazole for the Treatment of Fascioliasis and Paragonimiasis. Expert Opin. Invest. Drugs. 2005, 14, 1513. DOI: 10.1517/13543784.14.12.1513.
  • Doenhoff, M. J.; Cioli, D.; Utzinger, J. Praziquantel: Mechanisms of Action, Resistance and New Derivatives for Schistosomiasis. Curr. Opin. Infect. Dis. 2008, 21, 659. DOI: 10.1097/QCO.0b013e328318978f.
  • Doenhoff, M. J.; Pica-Mattoccia, L. Praziquantel for the Treatment of Schistosomiasis: Its Use for Control in Areas with Endemic Disease and Prospects for Drug Resistance. Expert Rev Anti Infect Ther. 2006, 4, 199. DOI: 10.1586/14787210.4.2.199.
  • Desie, S.; Dejene, G.; Jemere, B.; Yifat, D. J. Vet. Med. Anim. Health 2013, 5, 257.
  • Waller, P. J. Anthelmintic Resistance. Vet. Parasitol. 1997, 72, 391. DOI: 10.1016/s0304-4017(97)00107-6.
  • Jagadale, M. B.; Salunkhe, R. S.; Rajmane, M. M.; Dhanavade, M. J.; Sonawane, K. D.; Rashinkar, G. S. Water-Mediated Synthesis of Anthelmintic Piperidinols and Their Molecular Docking Studies. ChemistrySelect. 2018, 3, 5581. DOI: 10.1002/slct.201800375.
  • Kumar, R.; Joshi, Y. Arkivoc. 2007, 13, 142.
  • Kumar, R.; Joshi, Y. Synthesis and Antimicrobial, Antifungal and Anthelmintic Activities of 3h-1,5-Benzodiazepine Derivatives. J. Serb. Chem. Soc. 2008, 73, 937. DOI: 10.2298/JSC0810937K.
  • Sreena, K.; Ratheesh, R.; Rachana, M.; Poornima, M.; Shyni, C. Hygela. 2009, 1, 21.
  • Babu, I. S.; Selvakumar, S. An Antibacterial, Antifungal and Anthelmintic Evaluations of Some Synthesized Chalcone Derived Benzimidazoles. Biosci, Biotechnol. Res. Asia. 2013, 10, 891. DOI: 10.13005/bbra/1213.
  • Dutta, S. Synthesis and Anthelmintic Activity of Some Novel 2-substituted-4,5-diphenyl Imidazoles. Acta Pharm. 2010, 60, 229. DOI: 10.2478/v10007-010-0011-1.
  • Ouattara, M.; Sissouma, D.; Koné, M. W.; Menan, H. E.; Touré, S. A.; Ouattara, L. Trop. J. Pharm. Res. 2011, 10, 767.
  • Rossiter, S.; Peron, J.-M.; Whitfield, P. J.; Jones, K. Synthesis and Anthelmintic Properties of Arylquinolines with Activity against Drug-Resistant Nematodes. Bioorg. Med. Chem. Lett. 2005, 15, 4806. DOI: 10.1016/j.bmcl.2005.07.044.
  • Sawant, R.; Kawade, D. Synthesis and Biological Evaluation of Some Novel 2-Phenyl Benzimidazole-1-Acetamide Derivatives as Potential Anthelmintic Agents. Acta Pharm. 2011, 61, 353. DOI: 10.2478/v10007-011-0029-z.
  • Sharma, L. K.; Cupit, P. M.; Goronga, T.; Webb, T. R.; Cunningham, C. Design and Synthesis of Molecular Probes for the Determination of the Target of the Anthelmintic Drug praziquantel. Bioorg. Med. Chem. Lett. 2014, 24, 2469. DOI: 10.1016/j.bmcl.2014.04.014.
  • Sugawara, A.; Kubo, M.; Hirose, T.; Yahagi, K.; Tsunoda, N.; Noguchi, Y.; Nakashima, T.; Takahashi, Y.; Welz, C.; Mueller, D.; et al. Jietacins, Azoxy Antibiotics with Potent Nematocidal Activity: Design, Synthesis, and Biological Evaluation against Parasitic nematodes. Eur. J. Med. Chem. 2018, 145, 524. DOI: 10.1016/j.ejmech.2017.12.031.
  • Sharma, M.; Singhvi, I.; Ali, Z. M.; Kumar, M.; Dev, S. K. Synthesis and Biological Evaluation of Natural Cyclic Peptide. Fut. J. Pharm. Sci. 2018, 4, 220.
  • Ramesh, B.; Bhalgat, C. M. Novel Dihydropyrimidines and Its Pyrazole Derivatives: Synthesis and Pharmacological Screening. Eur. J. Med. Chem. 2011, 46, 1882. DOI: 10.1016/j.ejmech.2011.02.052.
  • Sudhir, M. S.; Nadh, R. V. J. Pharm. Res. 2013, 7, 47.
  • Chassaing, C.; Berger, M.; Heckeroth, A.; Ilg, T.; Jaeger, M.; Kern, C.; Schmid, K.; Uphoff, M. Highly Water-soluble Prodrugs of Anthelmintic Benzimidazole Carbamates: Synthesis, Pharmacodynamics, and Pharmacokinetics. J. Med. Chem. 2008, 51, 1111. DOI: 10.1021/jm701456r.
  • Kharmawlong, G. K.; Nongrum, R.; Chhetri, B.; Rani, J. W. S.; Rahman, N.; Yadav, A. K.; Nongkhlaw, R. Synth. Commun. 2019, 49, 2683–2695.
  • Shaikh, A.; Meshram, J. S. Cogent Chem. 2015, 1, 1.
  • Venkatesan, P.; Maruthavanan, T. Stereochemical Effect on Biological Activities of New Series of Piperidin-4-One Derivatives. Nat. Prod. Res. 2015, 29, 2092. DOI: 10.1080/14786419.2015.1009456.
  • Panda, S.; Nayak, S. Antibacterial, Antioxidant and Anthelmintic Studies of Inclusion Complexes of Some 4-Arylidenamino-5-Phenyl-4H-1,2,4-Triazole-3-Thiols. Supramol. Chem. 2015, 27, 679. DOI: 10.1080/10610278.2015.1075533.
  • Alam, F.; Dey, B. K.; Sharma, K.; Chakraborty, A.; Kalita, P. Int. J. Livest. Res. 2017, 4, 31. DOI: 10.5455/ijlr.20170729050423.
  • Shahare, M. B.; Kadam, V. J.; Jagdale, D. M.; Gandhi, P. S.; Gaikwad, P. L. Int. J. Res. Pharm. Chem. 2012, 2, 132.
  • Lakshmanan, B.; Mazumder, P. M.; Sasmal, D.; Ganguly, S.; Jena, S. S. Acta Parasitologica Globalis. 2011, 2, 1.
  • Kamal, R.; Kumar, R.; Kumar, V.; Kumar, V.; Bansal, K. K.; Sharma, P. C. Synthesis, Anthelmintic and Antimicrobial Evaluation of New 2‐Arylidene‐1‐(4‐Methyl‐6‐Phenylpyrimidin‐2‐yl)Hydrazines. ChemistrySelect. 2019, 4, 713. DOI: 10.1002/slct.201802822.
  • Sharma, K.; Jain, R. Indian J. Chem. 2012, 51B, 1462.
  • Bamnela, R.; Shrivastava, S. P. Indian J. Chem. 2014, 53B, 1128.
  • Munguía, B.; Mendina, P.; Espinosa, R.; Lanz, A.; Saldana, J.; J Andina, M.; Ures, X.; Lopez, A.; Manta, E.; Dominguez, L. Synthesis and Anthelmintic Evaluation of Novel Valerolactam- Benzimidazole Hybrids. Lddd. 2013, 10, 1007. DOI: 10.2174/15701808113109990028.
  • Yellasubbaiah, N.; Venumadhavi, A. M.; Sudha, B. N.; Rajkumar, T.; Harika, M. S.; Nagamani, B. Synthesis. 2018, 3, 23.
  • Sujani, C.; Radhika, K.; Rajasekhar, K. K.; Shankarananth, V. Int. J. Curr. Pharm. Sci. 2015, 5, 135. DOI: 10.22159/ijcpr.2017v9i4.20978.
  • Hareesh, S. R.; Venkatalakshmi, V.; Manoj Kumar, K. E.; Pk, K.; Dayananda, K. S. World J. Pharm. Res. 2017, 7, 735.
  • Gupta, S. K.; Kumar, N.; Pathak, D. Indian Drugs. 2013, 50, 01.
  • N'Guessan, J. P. D. U.; Delaye, P. O.; Penichon, M.; Charvet, C. L.; Neveu, C.; Ouattara, M.; Enguehard-Gueiffier, C.; Gueiffier, A.; Allouchi, H. Discovery of Imidazo[1,2-a]pyridine-based Anthelmintic Targeting Cholinergic Receptors of Haemonchus Contortus. Bioorg. Med. Chem. 2017, 25, 6695. DOI: 10.1016/j.bmc.2017.11.012.
  • Patra, M.; Ingram, K.; Pierroz, V.; Ferrari, S.; Spingler, B.; Keiser, J.; Gasser, G. Ferrocenyl Derivatives of the Anthelmintic Praziquantel: Design, Synthesis, and Biological Evaluation. J. Med. Chem. 2012, 55, 8790. DOI: 10.1021/jm301077m.
  • Piplani, M.; Rajak, H.; Sharma, P. C. Synthesis and Characterization of N-Mannich Based Prodrugs of Ciprofloxacin and Norfloxacin: In Vitro Anthelmintic and Cytotoxic evaluation. J. Adv. Res. 2017, 8, 463. DOI: 10.1016/j.jare.2017.06.003.
  • Scoccia, J.; Castro, M. J.; Faraoni, M. B.; Bouzat, C.; Martín, V. S.; Gerbino, D. C. Iron(II) Promoted Direct Synthesis of Dibenzo[b,e]Oxepin-11(6H)-One Derivatives with Biological Activity. A Short Synthesis of Doxepin. Tetrahedron. 2017, 73, 2913. DOI: 10.1016/j.tet.2017.03.085.
  • Patil, S. A.; Prabhakara, C. T.; Halasangi, B. M.; Toragalmath, S. S.; Badami, P. S. DNA Cleavage, Antibacterial, Antifungal and Anthelmintic Studies of Co(II), Ni(II) and Cu(II) Complexes of Coumarin Schiff Bases: Synthesis and Spectral approach. Spectrochim. Acta A Mol. Biomol. Spectrosc. 2015, 137, 641. DOI: 10.1016/j.saa.2014.08.028.
  • Manjunatha, M.; Naik, V. H.; Kulkarni, A. D.; Patil, S. A. DNA Cleavage, Antimicrobial, anti-Inflammatory Anthelmintic Activities, and Spectroscopic Studies of Co(II), Ni(II), and Cu(II) Complexes of Biologically Potential Coumarin Schiff Bases. J. Coord. Chem. 2011, 64, 4264. DOI: 10.1080/00958972.2011.621082.
  • Wadhwa, D.; Arora, V.; Arora, L.; Arora, P.; Parkash, O. Synthesis of Naphthalene Functionalized Trans-2,3-Dihydrofuro[3,2-c]Coumarins as Antioxidant and Anthelmintic Agents. J. Heterocyclic Chem. 2016, 53, 1030. DOI: 10.1002/jhet.2431.
  • Maddireddy, M.; Kulkarni, A. D.; Bagihalli, G. B.; Malladi, S. Thiosemicarbazone Scaffold as a Multidentate Ligand for Transition-Metal Ions: Synthesis, Characterization, in Vitro Antimicrobial, Anthelmintic, DNA Cleavage, and Cytotoxic Studies. Helv. Chim. Acta. 2016, 99, 562. DOI: 10.1002/hlca.201600045.
  • Gonzalez, I. C.; Davis, L. N.; Smith, C. K. II, Novel Thiophenes and Analogues with Anthelmintic Activity against Haemonchus contortus. Bioorg. Med. Chem. Lett. 2004, 14, 4037. DOI: 10.1016/j.bmcl.2004.05.044.
  • Sudha, B. N.; Sridhar, C.; Sastry, V. G.; Reddy, Y. S. R.; Sreevidya, O.; Lavanya, S.; Jyothi, V. A.; Nagesh, V.; Sen, S.; Chakraborty, R. Indian J. Chem. 2013, 52B, 422–427.
  • Satyendra, R. V.; Vishnumurthy, K. A.; Vagdevi, H. M.; Dhananjaya, B. L.; Shruthi, A. Synthesis, in Vitro Anthelmintic, and Molecular Docking Studies of Novel 5-Nitro Benzoxazole Derivatives. Med. Chem. Res. 2015, 24, 1342. DOI: 10.1007/s00044-014-1207-6.
  • Jeschke, P.; Harder, A.; Etzel, W.; Gau, W.; Thielking, G.; Bonse, G.; Iinuma, K. Synthesis and Anthelmintic Activity of Thioamide Analogues of Cyclic Octadepsipeptides Such as PF1022A. Pest. Manag. Sci. 2001, 57, 1000. DOI: 10.1002/ps.382.
  • Patel, K.; Jayachandran, E.; Shah, R.; Javali, V.; Sreenivasa, G. M. Int. J. Pharm. Biol. Sci. 2010, 1, 1.
  • Mondal, P.; Jana, S.; Balaji, A.; Ramakrishna, R.; Kanthal, L. K. Synthesis of Some New Isoxazoline Derivatives of Chalconised Indoline 2-one as a Potential Analgesic, Antibacterial and Anthelmimtic Agents. J. Young Pharm. 2012, 4, 38. DOI: 10.4103/0975-1483.93574.
  • Shaikh, A.; Meshram, J. Novel 1,3,4-Oxadiazole Derivatives of Dihydropyrimidinones: Synthesis, anti-Inflammatory, Anthelmintic, and Antibacterial Activity Evaluation. J. Heterocyclic Chem. 2016, 53, 1176. DOI: 10.1002/jhet.2377.
  • Kumari, V. A.; Bharathi, K. World J. Pharm. Res. 2018, 7, 1021.
  • Nadkarni, B.; Kamatb, V.; Khadse, B. Drug Res. 2001, 51, 569. DOI: 10.1055/s-0031-1300081.
  • Puthiyapurayil, P.; Poojary, B.; Chikkanna, C.; Buridipad, S. K. Synthesis, Spectral Characterization and Biological Evaluation of a Novel Series of 6-Arylsubstituted-3-[2-(4-Substitutedphenyl)Propan-2-yl]-7H-[1,2,4]Triazolo[3,4-b][1,3,4]Thiadiazines. Eur. J. Med. Chem. 2012, 57, 407. DOI: 10.1016/j.ejmech.2012.06.059.
  • Sharma, P. C.; Kumar, R.; Chaudhary, M.; Sharma, A.; Rajak, H. Synthesis and Biological Evaluation of Novel Benzothiazole Clubbed Fluoroquinolone Derivatives. J. Enzym Inhib. Med. Chem. 2013, 28, 1. DOI: 10.3109/14756366.2011.611943.
  • Munirajasekhar, D.; Himaja, M.; Mali, S. V. A Facile and Efficient Synthesis of 2-(5-(4-Substitutedphenyl)-4, 5-Dihydro-3-Phenylpyrazol-1-yl)-6-Substitutedbenzothiazoles and Their Biological Studies. J. Heterocyclic Chem. 2014, 51, 459. DOI: 10.1002/jhet.1618.
  • Amnerkar, N. D.; Bhusari, K. P. Synthesis of Some Thiazolyl Aminobenzothiazole Derivatives as Potential Antibacterial, Antifungal and Anthelmintic agents. J. Enzyme Inhib. Med. Chem. 2011, 26, 22. DOI: 10.3109/14756360903555258.
  • Amnerkar, N. D.; Bhongade, B. A.; Bhusari, K. P. Synthesis and Biological Evaluation of Some 4-(6-Substituted-1,3-Benzothiazol-2-yl)Amino-1,3-Thiazole-2-Amines and Their Schiff Bases. Arab. J. Chem. 2015, 8, 545. DOI: 10.1016/j.arabjc.2014.11.034.
  • Bhandari, N.; Gaonkar, S. L. Anthelmintic and Antibacterial Screening of a New Series of N-[4-(4-Nitrophenoxy)Phenyl]-4-(Substituted)-1,3-Thiazol-2-Amines. Russ. J. Bioorg. Chem. 2016, 42, 210. DOI: 10.1134/S1068162016020096.
  • Sarkar, S.; Dwivedi, J.; Chauhan, R. J. Pharm. Res. 2013, 7, 439. DOI: 10.1016/j.jopr.2013.05.008.
  • Partridge, F. A.; Forman, R.; Willis, N. J.; Bataille, C. J. R.; Murphy, E. A.; Brown, A. E.; Heyer-Chauhan, N.; Marinič, B.; Sowood, D. J. C.; Wynne, G. M.; et al. 2,4-Diaminothieno[3,2-d]Pyrimidines, a New Class of Anthelmintic with Activity against Adult and Egg Stages of Whipworm. PLoS Negl. Trop. Dis. 2018, 12, e0006487. DOI: 10.1371/journal.pntd.0006487.
  • Shankhdhar, P.; Saxena, V. World J. Pharm. Res. 2016, 5, 737.
  • Satyendra, R. V.; Vishnumurthy, K. A.; Vagdevi, H. M.; Rajesh, K. P.; Manjunatha, H.; Shruthi, A. Synthesis, In Vitro Antioxidant, Anthelmintic and Molecular Docking Studies of Novel Dichloro Substituted Benzoxazole-triazolo-thione Derivatives. Eur. J. Med. Chem. 2011, 46, 3078. DOI: 10.1016/j.ejmech.2011.03.017.
  • Kenchappa, R.; Bodke, Y. D.; Telkar, S.; Sindhe, M. A. Antifungal and Anthelmintic Activity of Novel Benzofuran Derivatives Containing Thiazolo Benzimidazole Nucleus: An in Vitro evaluation. J. Chem. Biol. 2017, 10, 11–23. DOI: 10.1007/s12154-016-0160-x.

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