NaNO₂-catalyzed reaction of cyclohexenone-MBH acetates: A convenient synthesis of 2-methylene-3-cyclohexenones

References

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• In the presence of acetic acid that is released from MBH acetate, NaNO2 seems not stable enough and is likely to generate NO2 and NO radicals. This kind of active intermediates would further undergo certain transformations. Some of the reported transformations in the presence of NaNO2 and acetic acid can be found in Ref. 17. For these reasons, though we have not carried out a detailed study, we speculate that these competitive reaction pathways would be more remarkable in the condition of increasing the load of NaNO2, and the product yield would be ruined as a result.
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