Improved Method of Dibromocyclopropane Derivatives Synthesis in Catalytic Two-Phase Reaction

References

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• NMR H1 spectra of new compounds (room temperature, CCl4 as a solvent, TMS as a internal standart, δ values): 1, 1-dibromo-2-n-butoxycyclopropane: triplet 0,95 (3H, J=6 Hz), multiplets 1,15–1, 93 (6H), 3,30–3,90 (3H). 1,1-dibromo-2,2-dimethyl-3-chloromethyl cyclopropane: 2 singlets 1,30 and 1,45 (2×3H), triplet 1,68 (1H, J=7,5 Hz), multiplet 3,25-3,92 (2H). n-Butyl 1-methyl-2,2-dibromocyclopropanecarboxylate: triplet 0,95 (3H, J=6 Hz), singlet 1,55 (3H), multiplet 1,1–2,0 (5H), two signals 2,25 and 2,38 (1H) - one of cyclopropane ring protons (the second one is overlaped by multiplet), triplet 4,13 (2H, J=6 Hz). (1, I=dibrmo-2,2-dimethyl) cyclopropylmethyl acetate: 2 singlets 1,25 and 1,40 (2×3H), triplet 1,58 (1H, J=7,5 Hz], singlet 2, OO (3H), dublet 4,05 (2H, J=7,5 Hz)
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• The product is unstable at room temperature, distillation at higher temp. results in decomposition
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• Despite rather wide temp. range the product is obtained in pure state (GLC)
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• The reaction was carried out at temp. below 30°C
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