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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 7, 1977 - Issue 4
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Original Articles

Synthesis of 11-Desoxy-8-azaprostaglandin E2

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Pages 299-303 | Received 30 Mar 1977, Published online: 23 Oct 2006

References

  • Undergraduate research participant.
  • Bruin , J. , DeKoning , H. and Huisman , H. O. 1975 . Tetrahedron Letters , : 4599
  • Nordin , I. C. 1966 . J. Heterocyclic Chem. , 3 : 531
  • The less polar diastereoisomer was tentatively assigned to the 15β-epimer 8b in analog with the characteristic tlc behavior of the natural carbocyclic prostaglandins.
  • Elemental analysis were consistent for all structures proposed.
  • Forehand , Mr. J. We would like to thank for mass spectra data;Mr. M. Stone for micro analysis; and Mr. A. F. Johnson, Jr. for coordinating the data obtained from the A. H. Robins Pharmaceutical Co., Richmond, Virginia.

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