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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 9, 1979 - Issue 10
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Original Articles

A Novel Synthesis of Berbines1-Synthesis of 2,3-Dimethoxy-10,11-Methylenedioxyberbine by Use of Palladium Catalyzed Insertion of Carbon Monoxide

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Pages 895-900 | Received 21 Jun 1979, Published online: 06 Dec 2006

References

  • The skeleton I is named as 5,8,13,13a-tetrahydro-6H-dibenzo- [a,g] quinolizine or alternatively 5,6,13,13a, 8H-dibenzo [a,g] quinolizine. Recently much less Cumbersome name ‘berbine’ has been used to replace somewhat complex nomenclature implicit in two other names as tetrahydroprotoberberine and tetrahydroberberine
  • Mori , M. , Chiba , K. and Ban , Y. 1977 . K. Chiba at the 97th annual meeting of Pharmaceutical Society of Japan . April 5 1977 , Tokyo.
  • Shamma , M. 1972 . “The isoquinoline Alkaloids - Chemistry and Pharmacology” , 268 317 New York and London : Adademic press .
  • This is the first literature record of compounds 2, 3, 4 and 5
  • Suguna , H. and Pai , B. R. 1977 . Ind. J. Chem. , 15B : 416
  • All m.p.'s are uncorrected and are recorded on a ‘Toshniwal’ melting point apparatus. All tlc was done on Silicagel G (Merck). IR spectra were recorded on a Perkin Elmer 337 spectrophotometer. NMR spectra were recorded on a varian associates A-6 spectrometer using TMS as an internal standard

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