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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 10, 1980 - Issue 12
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Original Articles

Studies on a General Method for the Demethylation of Quaternized Nitrogen Heterocycles

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Pages 947-950 | Published online: 05 Dec 2006

References

  • Kutney , J. P. and Greenhouse , R. 1975 . Synth. Commun. , 5 : 119
  • Berg , U. , Gallo , R. and Metzger , J. 1976 . J. Org. Chem. , 41 : 2621
  • Deady , L. W. and Korytsky , O. L. 1979 . Tetrahedron Lett. , : 451
  • Zoltewicz , J. A. and Deady , L. W. 1978 . Adv. Heterocycl. Chem. , 22 : 71 and references therein
  • The demethylation reaction has Ea ≃ 38 kcal, so a high reaction temperature can markedly reduce the necessary reaction time

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