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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 12, 1982 - Issue 2
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Original Articles

A Modified Polymer support for Organic Synthesis

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Pages 113-116 | Published online: 05 Dec 2006

References

  • Merrifield , R. B. 1963 . J. Am. Chem. Soc. , 85 : 2149
  • Gutte , B. and Merrifield , R. B. 1969 . ibid , 91 : 501
  • Stewart , J. M. and Young , J. D. 1969 . Solid Phase Peptide Synthesis San Francisco : W. H. Freeman and Co. .
  • Dixit , D. M. 1976 . Ph. D. Thesis, Carleton University, Ottawa
  • Leznoff , C. C. 1974 . Accts. Chem. Soc. Revs. , 3 : 1 For other examples of polymer supported syntheses see
  • Other examples of modified polymers are described in
  • Cramer , F. and Koster , H. 1968 . Angew. Chem. Internat. Edn. , 7 : 473
  • Kusama , T. K. and Hayatsu , H. 1970 . Chem. Pharm. Bull. , 18 : 319
  • Guthrie , R. D. , Jenkins , A. D. and Stehlicek , J. 1971 . J. Chem. Soc. (c) , : 2690
  • Zehavi , V. and Patchornik , A. 1973 . J. Am. Chem. Soc. , 95 : 5673
  • Felix , A. M. and Merrifield , R. B. 1970 . J. Amer. Chem. Soc. , 92 : 1385
  • Harrison , I. T. and Harrison , S. 1962 . (J. Amer. Chem. Soc. , 89 : 5723 The work of in effect uses this type of polymerbut the succinoyl residue is attachedvia the supported substrate as shown: Our simple and logical extension of this procedure appears to have the advantage of a very mild attachment route to the polymer (DCCD) as well using a preformed, stable solid support
  • Letsinger , R. L. , Kornet , M. J. , Mahadevan , V. and Jerina , D. M. 1964 . J. Am. Chem. Soc. , 86 : 5163 J. Rebels and F. Gavina, ibid 97, 3221 (1975)
  • Yip , K. F. and Tsou , K. C. 1971 . J. Amer. Chem. Soc. , 93 : 3272
  • Blossey , E. C. , Turner , L. M. and Neckers , D. C. 1975 . J. Org. Chem. , 40 : 959

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