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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 14, 1984 - Issue 9
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Original Articles

Preparation of Nitriles by Dehydration of Primary Carboxawides with a Supported phosphorus pentoxide reagent

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Pages 883-887 | Published online: 19 Dec 2006

References

  • Olah , G , Vankar , Y. D. and Garcia-Luna , A. 1979 . Synthesis , : 227 Recent reports include Barger, T.M. and Riley, C.M., Synth. Commun., 1980, 10(6), 479; and Yokoyama, M., Yoshida, S., and lmamoto, T., Synthesis, 1982, 591.
  • Scholl , R. 1896 . Chem. Ber. , 29 : 2415 Steinkopf, W., Chem. Ber., 1908, 41, 2540; Moureu, C. and Brown, R. L., Bull. Soc. Chim. Fr., 1920, 27, 901; Walter, L.A. and McElvain, S.M., J. Am. Chem. Soc., 1934, 56, 1614; and Kent, R.E. and McElvain, S.M., Org. Synth.; 1945, 25, 61. In these procedures the dry reagents were heated in the absence of solvent. For a variant method, in which the reagents were heated in refluxing trimethylbenzene (b.p. 166-174°), see Reisner, D.B. and Horning, E.C., Org. Synth., 1950, 30, 22.
  • Phosphorus pentoxide on an inert mineral support, supplied by E. Merck as 'SICAPENT'[rgrave] [with indicator. (Cat. No. 543)]. The indicator permits ready assessment of the quality of previously opened containers. [The preparation is also available without indicator. (Cat. No. 542).]
  • “ CRC Handbook of Chemistry and Physics ” . Vol. 59th Ed. , 1978 – 1979 . Boca Raton : CRC Press, Inc .

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