The Wittig Reaction Using Potassium-tert-butoxide High Yield Methylenations of Sterically Hindered Ketones

References

• Seyferth , D. , Hughes , W. B. and Heeren , J. K. 1965 . J. Am. Chem. Soc. , 87 : 2847
   Web of Science ®Google Scholar
• Bestmann , H. J. and Denzel , T. 1966 . Tetrahedron Lett. , : 3591 One of the most striking examples is the formation of a butylidenephosphorane by action of n-butyllithium on cyclopropyltriphenylphosphonium bromide
   Web of Science ®Google Scholar
• Corey , E. J. and Chaykovsky , M. 1962 . J. Am. Chem. Soc. , 84 : 866 Greenwald, R., Chaykovsky, M. and Corey, E. J., J. Org. Chem., 1963, 28, 1128. Formation of benzene was observed during the methylenation of both 14) and 35)
   Web of Science ®Google Scholar
• Wittig , G. and Schöllkopf , U. 1973 . Org. Syntheses , Vol. 5 : 751 Coll
   Google Scholar
• Abruscato , G. J. , Binder , R. G. and Tidwell , T. T. 1972 . J. Org. Chem. , 37 : 1787
   Web of Science ®Google Scholar
• Schlosser , M. and Christmann , K. F. 1964 . Angew. Chem. , 76 : 683 Angew. Chem. Int. Ed. Engl., 1964, 3, 636
   Google Scholar
• Greene , A. E. , Deprès , J. P. , Meana , M. C. and Crabbé , P. 1976 . Tetrahedron Lett. , : 3755 It has been reported that potassium methylsulfinate is easier to prepare and gives better reproducibility than sodium methylsulfinate
   Web of Science ®Google Scholar
• Enzell , C. R. and Thomas , B. R. 1965 . Acta Chem. Scand. , 19 : 1875 For one of the first examples see
   Google Scholar
• Corey , E. J. and Kang , J. 1982 . J. Am. Chem. Soc. , 104 : 4724 Corey, E. J., Kang, J. and Kyler, K., Tetrahedron Lett., 1985, 555; yield and reagent have been questioned10, 11)
   Web of Science ®Google Scholar
• Schlosser , M. , Tuong , H. B. , Respondek , J. and Schaub , B. 1983 . Chimia , 37 : 10
   Web of Science ®Google Scholar
• Schaub , B. , Jenny , T. and Schlosser , M. 1984 . Tetrahedron Lett. , : 4097 Schaub, B. and Schlosser, M., ibid., 1985, 1623
   Web of Science ®Google Scholar
• Mc Murry , J. E. 1968 . J. Am. Chem. Soc. , 90 : 6821 Kido F., Uda H., Yoshikoshi A., Chem. Commun., 1969, 1335; Boeckman Jr., R. K. and Silver, S. M., Tetrahedron Lett., 1973, 3497; Mc Murry, J. E. and Choy, W., ibid., 1980, 2477
   Web of Science ®Google Scholar
• Schlosser , M. and Schaub , B. 1982 . Chimia , 36 : 396 4-tert-Butylcyclohexanone instead of cyclohexanone
   Web of Science ®Google Scholar
• Bestmann , H. J. and Stransky , W. 1974 . Synthesis , : 798
   Web of Science ®Google Scholar
• Bestmann , H. J. , Stransky , W. and Vostrowsky , O. 1976 . Chem. Ber. , 109 : 1694
   Google Scholar
• Sevin , A. and Cense , J. M. 1974 . Bull. Soc. Chim. France , : 963
   Google Scholar
• Johnson , C. R. and Elliott , R. C. 1982 . J. Am. Chem. Soc. , 104 : 7041
   Web of Science ®Google Scholar
• Conia , J. M. and Limasset , J. C. 1967 . Bull. Soc. Chim. France , : 1936
   Google Scholar
• Takai , K. , Hotta , Y. , Oshima , K. and Nozaki , H. 1978 . Tetrahedron Lett. , : 2417 Bull. Chem. Soc. Japan, 1980, 53, 1698
   Web of Science ®Google Scholar
• Clawson , L. , Buchwald , S. L. and Grubbs , R. H. 1984 . Tetrahedron Lett. , : 5733
   Web of Science ®Google Scholar
• Heathcock , C. H. , Buse , C. T. , Kleschick , W. A. , Pirrung , M. C. , Sohn , J. E. and Lampe , J. 1980 . J. Org. Chem. , 45 : 1066
   Web of Science ®Google Scholar
• Hartzler , H. D. 1971 . J. Am. Chem. Soc. , 93 : 4527
   Web of Science ®Google Scholar
• Krawlec , Z. , Gonnord , M. F. , Guichon , G. and Chrétien , J. R. 1979 . Anal. Chem. , 51 : 1655
   Web of Science ®Google Scholar
• Dimmel , D. R. and Fu , W. Y. 1973 . J. Org. Chem. , 38 : 3778
   Web of Science ®Google Scholar
• Hellmann , S. , Beckhaus , H. D. and Rüchardt , C. 1983 . Chem. Ber. , 116 : 2219
   Google Scholar
• Gerig , J. T. 1968 . J. Am. Chem. Soc. , 90 : 1065
   Web of Science ®Google Scholar
• Shiner , V. J. Jr. and Meier , G. F. 1966 . J. Org. Chem. , 31 : 137
   Web of Science ®Google Scholar
• Grover , S. H. and Stothers , J. B. 1975 . Can. J. Chem. , 53 : 589
   Web of Science ®Google Scholar
• Werstiuk , N. H. , Tailefer , R. , Bell , R. A. and Sayer , B. G. 1972 . Can. J. Chem. , 50 : 2146 Morris, D. G. and Murray, A. M., J. Chem. Soc., Perkin Trans. 2, 1975, 539
   Web of Science ®Google Scholar
• Abruscato , G. J. , Ellis , P. D. and Tidwell , T. T. 1972 . J. Chem. Soc., Chem. Commun. , : 988
   Google Scholar