The Mono-Iodination of 3-Chloro-6-(2-Methoxybenzyl)-Pyridazine

References

• Gallos , J. and Varvoglis , A. 1981 . J. Chem. Res. (M). , : 1649
   Google Scholar
• Merkushev , E. B. , Simakhina , N. D. and Koveshnikova , G. M. 1980 . Synthesis , : 486
   Google Scholar
• Baird , W. and Surridge , J. 1970 . J. Org. Chem. , 35 : 3436
   Web of Science ®Google Scholar
• Sandin , R. B. , Drake , W. V. and Leger , F. 1943 . Org Syn. , Vol 2 : 196 Coll
   Google Scholar
• Woolet , G. H. and Johnson , W. W. 1943 . Org Syn. , Vol 2 : 343 Coll
   Google Scholar
• Wallingford , V. H. and Krueger , P. A. 1943 . Org Syn. , Vol 2 : 349 Coll
   Google Scholar
• Ali , S. M. and Ilyas , M. 1985 . Chem Ind., 16th , June : 426
   Google Scholar
• Nakazawa , K. 1962 . Chem. Pharm. Bull. , 10 : 1032
   Google Scholar
• Papa , D. , Schwenk , E. and Klingsberg , E. 1950 . J. Amer. Chem. Soc. , 72 : 2623
   Google Scholar
• Janssen , D. 1963 . Org. Syn. , Vol 4 : 547 Coll
   Google Scholar
• Sugiyama , T. 1981 . Bull. Chem. Soc. Jpn. , 54 : 2847
   Web of Science ®Google Scholar
• Wirth , H. O. , Konigstein , O. and Kern , W. 1960 . Ann. , 634 : 84
   Google Scholar
• Suzuki , H. , Nakamura , K. and Goto , R. 1966 . Bull. Chem. Soc. Jpn. , 39 : 128
   Web of Science ®Google Scholar
• Suzuki , H. 1971 . Org. Syn. , 51 : 94
   Google Scholar
• Horiuchi , C. A. 1982 . J. Chem. Soc. Chem. Commun. , : 671
   Google Scholar
• Horiuchi , C. A. and Satoh , J. Y. 1984 . Bull. Chem. Soc. Jpn. , 57 : 2691
   Google Scholar
• Ogata , Y. and Nakajima , K. 1964 . Tetrahedron , 20 : 43
   Google Scholar
• Ogata , Y. and Aoki , K. 1968 . J. Amer. Chem. Soc. , 90 : 6187
   Google Scholar
• Sax , N. I. 1984 . Dangerous Properties of Industrial Materials , 6th Edition , 82 and 2002 New York : van Nostrand Reinhold .
   Google Scholar
• Minisci , F. , Citterio , A. and Giordano , C. 1983 . Acc. Chem. Res. , 16 : 27
   Web of Science ®Google Scholar
• Beringer , F. M. , Falk , R. A. , Karniol , M. , Lillien , I. , Masullo , G. , Mausner , M. and Sommer , E. 1959 . J. Amer. Chem. Soc. , 81 : 342
   Google Scholar
• Beringer , F. M. and Lillien , I. 1960 . J. Amer. Chem. Soc. , 82 : 725
   Google Scholar
• Lewis , N. J. and O'Farrell , C. submitted for publication
   Google Scholar
• Registered Trademark of the DuPont Co
   Google Scholar
• Reactions were followed by hplc on C18 μbondapak column eluted with 55% acetonitrile in water containing 1g/L of camphor sulphonic acid. Detector 290nm, flow rate 1ml/min. Compound (1) Rt ≍ 6.3 min, compound (2) Rt ≍ 10.5 min. PAR = Peak Area Ratio
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• For hplc assay the following conditions were used: C18: C18 μbondapak column eluted with 10–70% acetonitrile in phosphoric acid (5ml/L) at pH = 2.2 (with 10M KOH) over 30 min, at 40°C. Flow rate 1 ml/min, detector 275nm, compound (1) Relative Rt = 0.70 and response factor 0.71, compound (2) Relative Rt = 1.00
   Google Scholar