Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 18, 1988 - Issue 9
28
Views
5
CrossRef citations to date
0
Altmetric
Original Articles

Facile Synthesis of 1,2-Dialkyl-3-Phenyl-4-Quinolinones

Pages 995-1008 | Published online: 05 Dec 2006

References

  • Coppola , G. M. 1982 . J. Heterocyclic. Chem. , 19 : 727
  • Coppola , G. M. 1983 . Synthesis , : 939
  • Coppola , G. M. 1985 . J. Heterocyclic Chem. , 22 : 491
  • Coppola , G. M. 1980 . Synthesis , : 505
  • Kappe , T. and Stadlbauer , W. 1981 . “Advances in Heterocyclic Chemistry,” , Vol. 28 , 127 New York : Academic Press .
  • An extra equivalent of phenylacetone enolate is required to satisfy the highly acidic protons in intermediate 2. Presumably, at this stage the initially formed 2 still contains a carboxylate anion attached to the anilino nitrogen (-NRCOOLi)
  • Potassium hexamethyldi silazide is commercially available from Callery Chemical Co., Callery, PA.
  • Boeckman , R. K. Jr. and Bruza , K. J. 1977 . Tetrahedron Lett. , : 4187
  • Oakes , F. T. and Sebastian , J. F. 1980 . J. Org. Chem. , 45 : 4959

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.