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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 18, 1988 - Issue 11
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Original Articles

High Yield Synthesis of α Propargylic Acrylic Ester: A General Access to α Substituted Acrylic Esters

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Pages 1213-1223 | Published online: 06 Dec 2006

References

  • Kirschleger , B. and Queignec , R. 1986 . Synthesis , : 927
  • Ravikuman , V. T. , Thangaraj , K. , Swaminathan , S. and Rajagapalan , K. 1985 . Synthesis , : 985 and references cited therein
  • Kirschleger , B. and Queignec , R. 1985 . C.R. Acad. Sci. , : 301 The same reaction with ethyl acetylacetate gives 10 % of dipropargylated product, see, II, 143
  • Tsuboi , S. , Uno , T. and Takeda , A. 1978 . Chem. Lett. , : 1325
  • Ueno , Y. , Setai , H. and Okawara , M. 1978 . Tetrahedron Lett. , : 3753
  • A limitation has been found in a attempt to synthesise the homologous β and α substituted acrylate esters because aldehydes and ketones are unreactive towards the monosubsti-tuted keto ester anion
  • Miller , R. B. and Smith , B. F. 1973 . Synth. Comm. , 3 : 359 MARINO J.P., FLOYD D.M., J. Am. Chem. Soc., 1974, 96, 7138, See reference 1 and references cited therein
  • Ethylbenzoylacetate slighty decomposes in the light giving acetophenone as a by-product. It must be stored in the refrigerator or in the dark

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