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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 24
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Original Articles

Nitrilotriacetamide: Synthesis in Concentrated Sulfuric Acid and Stability in Water

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Pages 4123-4132 | Received 15 May 1995, Published online: 23 Sep 2006

References

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  • Smith , D. and Finnen , D. C. manuscript in preparation. This compound has not previously been characterized in the literature. In addition to the data reported herein, we have determined the x-ray structure of this compound:
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  • Direct, single step conversion of nitriles to amides can also be accomplished using 30% H2O2 and 6N NaOH; see Org. Synth. Coll. Vol. II, 586. All attempts to convert 2 to 1 under these conditions proceeded vigorously but failed to produce any clean or identifiable products
  • Skrzypczak-Jankun , E. and Smith , D. A. unpublished results. Full details will be reported elsewhere. P212121, a = 5.5211(1), b = 22.668(2), c = 7.044(1)Å, Z = 4, dc = 1.50 g/cm−3

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