An Optimized Synthesis of 2-Methoxyestradiol, A Naturally Occurring Human Metabolite with Anticancer Activity

References

• Breuer , H. and Knuppen , R. 1960 . Naturwissenschaften , 12 : 280 – 281 .
   Google Scholar
• Gelbke , H. P. and Knuppen , R. 1976 . J. Steroid Biochem. , 7 : 457 – 463 .
   PubMedGoogle Scholar
• D'Amato , R. J. , Lin , C. M. , Flynn , E. , Folkman , J. and Hamel , E. 1994 . Proc. Natl. Acad. Sci. U.S.A. , 91 : 3964 – 3968 .
   PubMed Web of Science ®Google Scholar
• Hamel , E. , Lin , C. M. , Flynn , E. and D'Amato , R. J. 1996 . Biochemistry , 35 : 1304 – 1310 .
   PubMed Web of Science ®Google Scholar
• Seegers , J. C. , Aveling , M.-L. , van Aswegen , C. H. , Cross , M. , Koch , F. and Joubert , W. S. 1989 . J. Steroid Biochem. , 32 : 797 – 809 .
   PubMedGoogle Scholar
• Lottering , M.-L. , Haag , M. and Seegers , J. C. 1992 . Cancer Res. , 52 : 5926 – 5932 .
   PubMed Web of Science ®Google Scholar
• Attalla , H. , Makela , T. P. , Adlercrcutz , H. and Andersson , L. C. 1996 . Biochem. Biophys. Res. Commun. , 228 : 467 – 473 .
   PubMed Web of Science ®Google Scholar
• Fotsis , T. , Zhang , Y. , Pepper , M. S. , Adlercreutz , H. , Montesano , R. , Nawroth , P. P. and Schweigerer , L. 1994 . Nature , 368 : 237 – 239 .
   PubMed Web of Science ®Google Scholar
• Klauber , N. , Parangi , S. , Hamel , E. , Flynn , E. and D'Amato , R. J. 1997 . Cancer Res. , 57 : 81 – 86 .
   PubMed Web of Science ®Google Scholar
• Yue , T. L. , Wang , X. K. , Louden , C. S. , Gupta , S. , Pillarisetti , K. , Gu , J. L. , Hart , T. K. , Lysko , P. G. and Feuerstein , G. Z. 1997 . Mol. Pharmacol. , 51 : 951 – 962 .
   PubMed Web of Science ®Google Scholar
• Josefsson , E. and Tarkowski , A. 1997 . Arthritis Rheum. , 40 : 154 – 163 .
   PubMed Web of Science ®Google Scholar
• Pert , D. J. and Ridley , D. D. 1989 . Aust. J. Chem. , 42 : 405 – 419 .
   Google Scholar
• Lovely , C. J. , Gilbert , N. E. , Liberto , M. M. , Sharp , D. W. , Lin , Y. C. and Brueggemeier , R. W. 1996 . J. Med. Chem. , 39 : 1917 – 1923 .
   PubMedGoogle Scholar
• Fishman , J. 1958 . J. Am. Chem. Soc. , 80 : 1213 – 1216 .
   Web of Science ®Google Scholar
• Nambara , T. , Honma , S. and Akiyama , S. 1970 . Chem. Pharm. Bull. , 1970 : 474 – 480 .
   Google Scholar
• Rao , P. N. and Burdett , J. E. Jr. 1977 . Synthesis , : 168 – 169 .
   Google Scholar
• Chen , S.-h. , Luo , G.-r. , Wu , X.-s. , Chen , M. and Zhao , H.-M. 1986 . Steroids , 47 : 63 – 68 .
   PubMedGoogle Scholar
• Numazawa , M. and Ogura , Y. 1983 . J. Chem. Soc., Chem. Commun. , : 533 – 534 .
   Google Scholar
• Numazawa , M. , Ogura , Y. , Kimura , K. and Nagaoka , M. 1985 . J. Chem. Res. (M) , : 3701 – 3709 .
   Google Scholar
• He , H.-M. and Cushman , M. 1994 . Bioorg. Med. Chem. Lett. , 4 : 1725 – 1728 .
   Google Scholar
• Cushman , M. , He , H.-M. , Katzenellenbogen , J. , Varma , R. K. , Hamel , E. , Lin , C. M. , Ram , S. and Sachdeva , Y. P. 1997 . J. Med. Chem. , 40 : 2323 – 2334 .
   PubMedGoogle Scholar
• Cushman , M. , He , H.-M. , Katzenellenbogen , J. A. , Lin , C. M. and Hamel , E. 1995 . J. Med. Chem. , 38 : 2041 – 2049 .
   PubMed Web of Science ®Google Scholar
• Miller , T. A. , Bulman , A. L. , Thompson , C. D. , Garst , M. E. and Macdonald , T. L. 1997 . J. Med. Chem. , 40 : 3836
   PubMedGoogle Scholar