References
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- General procedure for the preparation of thiourea 5a-l: To a stirred solution of the amine 3 (30 mmol) in CH2C12 (50 ml) was added isothiocyanate 4 (33 mmol) and stirring was continued for 2 hours at room temperature. After evaporation of the solvent under reduced pressure, the residue was crystallised from hexane
- General procedure for the preparation of thioether 6a-l: To a stirred solution of thiourea 5 (25 mmol) in acetone (40 ml) was added CH3I (75 mmol) and the resulting mixture was stirred further for 1 hour at room temperature. Evaporation of the solvent and crystallisation of the residue afforded thioether 6
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- Lecher , H. Z. , Parker , R. P. and Long , R. S. 1946 . Am. Cyanamid Co . US Patent 2455894; C. A 43: 1799c