Vaccines against bovine mastitis in the New Zealand context: What is the best way forward?

References

• Almeida , RA and Oliver , SP . 1995 . Phagocytosis of Streptococcus uberis by bovine mammary macrophages: opsonizing effect of bovine antiserum . Zentralblatt für Veterinärmedizin B , 42 : 331 – 337 .
   PubMedGoogle Scholar
• Almeida , RA , Fang , W and Oliver , SP . 1999 a . Adherence and internalization of Streptococcus uberis to bovine mammary epithelial cells are mediated by host cell proteoglycans . FEMS Microbiology Letters , 177 : 313 – 317 .
   PubMed Web of Science ®Google Scholar
• Almeida , RA , Luther , DA and Oliver , SP . 1999 b . Incubation of Streptococcus uberis with extracellular matrix proteins enhances adherence to and internalization into bovine mammary epithelial cells . FEMS Microbiology Letters , 178 : 81 – 85 .
   PubMed Web of Science ®Google Scholar
• Almeida , RA , Luther , DA , Park , HM and Oliver , SP . 2006 . Identification, isolation, and partial characterization of a novel Streptococcus uberis adhesion molecule (SUAM) . Veterinary Microbiology , 115 : 183 – 191 .
   PubMed Web of Science ®Google Scholar
• Anderson , JC . 1985 . “ The prospect of immunization against mastitis ” . In Progress in the Control of Bovine Mastitis , 524 – 527 . Gelsenkirchen-Buer, , Germany : Verlag .
   Google Scholar
• Anonymous Seasonal Approach to Managing Mastitis National Mastitis Advisory Committee Wellington, , NZ 2005
   Google Scholar
• Bannerman , DD , Paape , MJ , Goff , JP , Kimura , K , Lippolis , JD and Hope , JC . 2004 . Innate immune response to intramammary infection with Serratia marcescens and Streptococcus uberis . Veterinary Research , 35 : 681 – 700 .
   PubMed Web of Science ®Google Scholar
• Barrio , B , Vangroenweghe , F , Dosogne , H and Burvenich , C . 2000 . Decreased neutrophil bactericidal activity during phagocytosis of a slime-producing Staphylococcus aureus strain . Veterinary Research , 31 : 603 – 609 .
   PubMed Web of Science ®Google Scholar
• Barrio , MB , Rainard , P and Poutrel , B . 2003 . Milk complement and the opsonophagocytosis and killing of Staphylococcus aureus mastitis isolates by bovine neutrophils . Microbial Pathogenesis , 34 : 1 – 9 .
   PubMed Web of Science ®Google Scholar
• Bosworth , BT , Dowbenko , D , Shuster , DE and Harp , JA . 1993 . Bovine L-selectin: a peripheral lymphocyte homing receptor . Veterinary Immunology and Immunopathology , 37 : 201 – 215 .
   PubMed Web of Science ®Google Scholar
• Brouillette , E , Grondin , G , Shkreta , L , Lacasse , P and Talbot , BG . 2003 . In vivo and in vitro demonstration that Staphylococcus aureus is an intracellular pathogen in the presence or absence of fibronectin-binding proteins . Microbial Pathogenesis , 35 : 159 – 168 .
   PubMed Web of Science ®Google Scholar
• Buescher , ES . 2001 . Anti-inflammatory characteristics of human milk: how, where, why . Advances in Experimental Medicine and Biology , 501 : 207 – 222 .
   PubMed Web of Science ®Google Scholar
• Burvenich , C , Van , Merris , Mehrzad , J , Diez-Fraile , A and Duchateau , L . 2003 . Severity of E. coli mastitis is mainly determined by cow factors . Veterinary Research , 34 : 521 – 564 .
   PubMed Web of Science ®Google Scholar
• Chang , Bs , Bohach , GA , Lee , SU , Davis , WC , Fox , LK , Ferens , WA , Seo , KS , Koo , HC , Kwon , NH and Park , YH . 2005 . Immunosuppression by T-regulatory cells in cows infected with staphylococcal superantigen . Journal of Veterinary Science , 6 : 247 – 250 .
   PubMedGoogle Scholar
• Chockalingam , A , McKinney , CE , Rinaldi , M , Zarlenga , DS and Bannerman , DD . 2007 . A peptide derived from human bactericidal/permeability-increasing protein (BPI) exerts bactericidal activity against Gram-negative bacterial isolates obtained from clinical cases of bovine mastitis . Veterinary Microbiology , 125 : 80 – 90 .
   PubMed Web of Science ®Google Scholar
• Compton , CWR , Cursons , RTM , Barnett , CME and McDougall , S . 2009 . Expression of innate resistance factors in mammary secretion from periparturient dairy heifers and their association with subsequent infection status . Veterinary Immunology and Immunopathology , 127 : 357 – 364 .
   PubMed Web of Science ®Google Scholar
• Denis , M , Parlane , NA , Lacy-Hulbert , SJ , Summers , EL , Buddle , BB and Wedlock , DN . 2006 . Bactericidal activity of macrophages against Streptococcus uberis is different in mammary gland secretions of lactating and drying off cows . Veterinary Immunology and Immunopathology , 114 : 111 – 120 .
   PubMed Web of Science ®Google Scholar
• Dosogne , H , Vangroenweghe , F and Burvenich , C . 2002 . Potential mechanism of action of J5 vaccine in protection against severe bovine coliform mastitis . Veterinary Research , 33 : 1 – 12 .
   PubMed Web of Science ®Google Scholar
• Endsley , JJ , Furrer , JL , Endsley , MA , McIntosh , MA , Maue , AC , Waters , WR , Lee , DR and Estes , DM . 2004 . Characterization of bovine homologues of granulysin and NK-lysin . Journal of Immunology , 173 : 2607 – 2614 .
   PubMed Web of Science ®Google Scholar
• Field , TR , Norton , PM , Bland , AP and Leigh , JA . 1997 . Changes in bovine neutrophils induced by the capsule of Streptococcus uberis . Advances in Experimental Medicine and Biology , 418 : 957 – 960 .
   PubMed Web of Science ®Google Scholar
• Field , TR , Ward , PN , Pedersen , LH and Leigh , JA . 2003 . The hyaluronic acid capsule of Streptococcus uberis is not required for the development of infection and clinical mastitis . Infection and Immunity , 71 : 132 – 139 .
   PubMed Web of Science ®Google Scholar
• Finch , JM , Hill , AW , Field , TR and Leigh , JA . 1994 . Local vaccination with killed Streptococcus uberis protects the bovine mammary gland against experimental intramammary challenge with the homologous strain . Infection and Immunity , 62 : 3599 – 3603 .
   PubMed Web of Science ®Google Scholar
• Finch , JM , Winter , A , Walton , AW and Leigh , JA . 1997 . Further studies on the efficacy of a live vaccine against mastitis caused by Streptococcus uberis . Vaccine , 15 : 1138 – 1143 .
   PubMed Web of Science ®Google Scholar
• Fontaine , MC , Perez-Casal , J , Song , X-M , Shelford , J , Wilson , PJ and Potter , AA . 2002 . Immunization of dairy cattle with recombinant Streptococcus uberis GapC or a chimeric CAMP antigen confers protection against heterologous bacterial challenge . Vaccine , 20 : 2278 – 2286 .
   PubMed Web of Science ®Google Scholar
• Gill , HS , Doull , F , Rutherfurd , KJ and Cross , ML . 2000 . Immunoregulatory peptides in bovine milk . British Journal of Nutrition , 84 ( Supplement 1 ) : 111 – 117 .
   PubMed Web of Science ®Google Scholar
• Goldberg , JJ , Pankey , JW , Politis , I , Zavizion , B and Bramley , AJ . 1995 . Effect of oxygen tension on killing of Escherichia coli by bovine polymorphonuclear neutrophil leucocytes in vitro . Journal of Dairy Science , 62 : 331 – 338 .
   Google Scholar
• González , RN , Cullor , JS , Jasper , DE , Farver , TB , Bushnell , RB and Oliver , MN . 1989 . Prevention of clinical coliform mastitis in dairy cows by a mutant Escherichia coli vaccine . Canadian Journal of Veterinary Research , 53 : 301 – 305 .
   PubMed Web of Science ®Google Scholar
• Grant , RG and Finch , JM . 1997 . Phagocytosis of Streptococcus uberis by bovine mammary gland macrophages . Research in Veterinary Science , 62 : 74 – 78 .
   PubMed Web of Science ®Google Scholar
• Groschup , MH and Timoney , JF . 1993 . An R-like protein of Streptococcus uberis stimulates opsonising antibodies . Research in Veterinary Science , 54 : 124 – 126 .
   PubMed Web of Science ®Google Scholar
• Harp , JA , Stabel , JR , Pesch , BA and Goff , JP . 2004 a . Expression of adhesion molecules on milk and blood lymphocytes from periparturient dairy cattle with Johne's disease . Veterinary Immunology and Immunopathology , 98 : 69 – 76 .
   PubMed Web of Science ®Google Scholar
• Harp , JA , Waters , TE and Goff , JP . 2004 b . Lymphocyte subsets and adhesion molecule expression in milk and blood of periparturient dairy cattle . Veterinary Immunology and Immunopathology , 102 : 9 – 17 .
   PubMed Web of Science ®Google Scholar
• Harp , JA , Waters , TE , Goff , JP , Bannerman , DD and Paape , MJ . 2006 . Expression of lymphocyte homing and adhesion molecules during intramammary infection of cows with Serratia marcescens or Streptococcus uberis: correlation with bacterial colonization and clinical signs . Veterinary Immunology and Immunopathology , 109 : 13 – 21 .
   PubMed Web of Science ®Google Scholar
• Hébert , A , Sayasith , K , Sénéchal , S , Dubreuil , P and Lagacé , J . 2000 . Demonstration of intracellular Staphylococcus aureus in bovine mastitis alveolar cells and macrophages isolated from naturally infected cow milk . FEMS Microbiology Letters , 193 : 57 – 62 .
   PubMed Web of Science ®Google Scholar
• Hill , AW . 1988 . Protective effect of previous intramammary infection with Streptococcus uberis against subsequent clinical mastitis in the cow . Research in Veterinary Science , 44 : 386 – 387 .
   PubMed Web of Science ®Google Scholar
• Hill , AW . 1991 . Vaccination of cows with rough Escherichia coli mutants fails to protect against experimental intramammary bacterial challenge . Veterinary Research Communications , 15 : 7 – 16 .
   PubMed Web of Science ®Google Scholar
• Hill , AW , Finch , JM , Field , TR and Leigh , JA . 1994 . Immune modification of the pathogenesis of Streptococcus uberis mastitis in the dairy cow . FEMS Immunology and Medical Microbiology , 8 : 109 – 117 .
   PubMedGoogle Scholar
• Hodgkinson , AJ , Carpenter , EA , Smith , CS , Molan , PC and Prosser , CG . 2007 . Adhesion molecule expression in the bovine mammary gland . Veterinary Immunology and Immunopathology , 115 : 205 – 215 .
   PubMed Web of Science ®Google Scholar
• Hoedemaker , M , Korff , B , Edler , B , Emmert , M and Bleckmann , E . 2001 . Dynamics of Staphylococcus aureus infections during vaccination with an autogenous bacterin . Journal of Veterinary Medicine B. Infectious Diseases and Veterinary Public Health , 48 : 373 – 383 .
   PubMedGoogle Scholar
• Hogan , JS , Todhunter , DA , Tomita , GM , Smith , KL and Schoenberger , PS . 1992 a . Opsonic activity of bovine serum and mammary secretion after Escherichia coli J5 vaccination . Journal of Dairy Science , 75 : 72 – 77 .
   PubMed Web of Science ®Google Scholar
• Hogan , JS , Smith , KL , Todhunter , DA and Schoenberger , PS . 1992 b . Field trial to determine efficacy of an Escherichia coli J5 mastitis vaccine . Journal of Dairy Science , 75 : 78 – 84 .
   PubMed Web of Science ®Google Scholar
• Hogan , JS , Weiss , WP , Todhunter , DA , Smith , KL and Schoenberger , PS . 1992 c . Efficacy of an Escherichia coli J5 mastitis vaccine in an experimental challenge trial . Journal of Dairy Science , 75 : 415 – 422 .
   PubMed Web of Science ®Google Scholar
• Howard , P . 2006 . Mastitis pathogens present in bulk tank milk from seven dairy herds in the Waikato region, New Zealand . New Zealand Veterinary Journal , 54 : 41 – 43 .
   PubMed Web of Science ®Google Scholar
• Hwang , C-Y , Pak , SI and Han , H-R . 2000 . Effects of autogenous toxoid-bacterin in lactating cows with Staphylococcus aureus subclinical mastitis . Journal of Veterinary Medical Science , 62 : 875 – 880 .
   PubMed Web of Science ®Google Scholar
• Jones , CL , Monaghan , P , Field , TR , Smith , AJ , Ward , PN and Leigh , JA . 2004 . Localization of MtuA, an LraI homologue in Streptococcus uberis . Journal of Applied Microbiology , 97 : 149 – 157 .
   PubMed Web of Science ®Google Scholar
• Kehrli , ME and Harp , JA . 2001 . Immunity in the mammary gland . Veterinary Clinics of North America, Food Animal Practice , 17 : 495 – 516 .
   PubMed Web of Science ®Google Scholar
• Lascelles , AK . 1979 . The immune system on the ruminant mammary gland and its role in the control of mastitis . Journal of Dairy Science , 62 : 154 – 167 .
   PubMed Web of Science ®Google Scholar
• Lee , JW , O'Brien , CN , Guidry , AJ , Paape , MJ , Shafer-Weaver , KA and Zhao , X . 2001 . Effect of a trivalent vaccine against Staphylococcus aureus mastitis lymphocyte subpopulations, antibody production and neutrophil phagocytosis . Canadian Journal of Veterinary Research , 69 : 11 – 18 .
   Google Scholar
• Leigh , JA . 1999 . Streptococcus uberis: a permanent barrier to the control of bovine mastitis . Veterinary Journal , 157 : 225 – 238 .
   PubMed Web of Science ®Google Scholar
• Leigh , JA . 2000 . Vaccines against bovine mastitis due to Streptococcus uberis: current status and future prospects . Advances in Experimental Medicine and Biology , 80 : 307 – 311 .
   Google Scholar
• Leigh , JA . 2002 . Re: ‘Immunization of dairy cattle with recombinant Streptococcus uberis GapC or a chimeric CAMP antigen confers protection against heterologous bacterial challenge’. . Vaccine , 20 : 3047 – 3048 . MC Fontaine et al (Vaccine 20, 2278-86, 2002)
   PubMed Web of Science ®Google Scholar
• Leigh , JA and Field , TR . 1994 . Streptococcus uberis resists the bactericidal action of bovine neutrophils despite the presence of bound immunoglobulin . Infection and Immunity , 62 : 1854 – 1859 .
   PubMed Web of Science ®Google Scholar
• Leigh , JA , Finch , JM , Field , TR , Real , NC , Winter , A , Walton , AW and Hodgkinson , SM . 1999 . Vaccination with the plasminogen activator from Streptococcus uberis induces an inhibitory response and protects against experimental infection in the dairy cow . Vaccine , 17 : 851 – 857 .
   PubMed Web of Science ®Google Scholar
• Leitner , G , Lubashevsky , E , Glickman , A , Winkler , M , Saran , A and Trainin , Z . 2003 . Development of a Staphylococcus aureus vaccine against mastitis in dairy cows 1, Challenge trials . Veterinary Immunology and Immunopathology , 93 : 31 – 38 .
   PubMed Web of Science ®Google Scholar
• Lopez-Benavides , MG , Williamson , JH , Pullinger , GD , Lacy-Hulbert , SJ , Cursons , RT and Leigh , JA . 2007 . Field observations on the variation of Streptococcus uberis populations in a pasture-based dairy farm . Journal of Dairy Science , 90 : 5558 – 5566 .
   PubMed Web of Science ®Google Scholar
• Lopez-Benavides , MG , Williamson , JH , Lacy-Hulbert , SJ and Cursons , RT . 2009 . Heifer teats sprayed in the dry period with an iodine teat sanitizer have reduced Streptococcus uberis teat-end contamination and less Streptococcus uberis intramammary infections at calving . Veterinary Microbiology , 134 ( Special Issue: Heifer and CNS Mastitis ) : 186 – 191 .
   PubMed Web of Science ®Google Scholar
• Malcolm , D . 2007 . Annual Proceedings of the National Mastitis Advisory Committee , : 136 – 137 .
   Google Scholar
• Mayer , SJ , Waterman , AE , Keen , PM , Craven , N and Bourne , FJ . 1988 . Oxygen concentration in milk of healthy and mastitic cows and implications of low oxygen tension for the killing of Staphylococcus aureus by bovine neutrophils . Journal of Dairy Science , 55 : 513 – 519 .
   Google Scholar
• McDougall , S . 2003 . Management factors associated with the incidence of clinical mastitis over the non-lactation period and bulk tank somatic cell count during the subsequent lactation . New Zealand Veterinary Journal , 51 : 63 – 72 .
   PubMed Web of Science ®Google Scholar
• McDougall , S , Arthur , DG , Bryan , MA , Vermunt , JJ and Weir , AM . 2007 . Clinical and bacteriological response to treatment of clinical mastitis with one of three intramammary antibiotics . New Zealand Veterinary Journal , 55 : 161 – 170 .
   PubMed Web of Science ®Google Scholar
• McDougall , S , Parker , KI , Heuer , C and Compton , CWR . 2009 . A review of prevention and control of heifer mastitis via non-antibiotic strategies . Veterinary Microbiology , 134 ( Special Issue: Heifer and CNS Mastitis ) : 177 – 185 .
   PubMed Web of Science ®Google Scholar
• Mehrzad , J , Dosogne , H , Meyer , E , Heyneman , R and Burvenich , C . 2001 . Respiratory burst activity of blood and milk neutrophils in dairy cows during different stages of lactation . Journal of Dairy Science , 68 : 399 – 415 .
   Google Scholar
• Mehrzad , J , Janssen , D , Duchateau , L and Burvenich , C . 2008 . Increase in Escherichia coli inoculum dose accelerates CD8+ T-cell trafficking in the primiparous bovine mammary gland . Journal of Dairy Science , 91 : 193 – 201 .
   PubMed Web of Science ®Google Scholar
• Mellenberger , RW . 1977 . Vaccination against mastitis . Journal of Dairy Science , 60 : 1016 – 1021 .
   PubMed Web of Science ®Google Scholar
• Middleton , JR , Ma , J , Rinehart , CL , Taylor , VN , Luby , CD and Steevens , BJ . 2006 . Efficacy of different Lysigin formulations in the prevention of Staphylococcus aureus intramammary infection in dairy heifers . Journal of Dairy Research , 73 : 10 – 19 .
   PubMed Web of Science ®Google Scholar
• Musser , JM and Anderson , KL . 1996 . Effect of vaccination with an Escherichia coli bacterintoxoid on milk production in dairy cattle . Journal of the American Veterinary Medical Association , 209 : 1291 – 1293 .
   PubMed Web of Science ®Google Scholar
• Nickerson , SC , Owens , WE and Boddie , RL . 1993 . Effect of a Staphylococcus aureus bacterin on serum antibody, new infection, and mammary histology in nonlactating dairy cows . Journal of Dairy Science , 76 : 1290 – 1297 .
   PubMed Web of Science ®Google Scholar
• Pankey , JW , Boddie , NT , Watts , JL and Nickerson , SC . 1985 . Evaluation of protein A and a commercial bacterin as vaccines against Staphylococcus aureus mastitis by experimental challenge . Journal of Dairy Science , 68 : 726 – 731 .
   PubMed Web of Science ®Google Scholar
• Park , YH , Fox , LK , Hamilton , MJ and Davis , WC . 1993 . Suppression of proliferative response of BoCD4p+ T lymphocytes by activated BoCD8+ T lymphocytes in the mammary gland of cows with Staphylococcus aureus mastitis . Veterinary Immunology and Immunopathology , 36 : 137 – 151 .
   PubMed Web of Science ®Google Scholar
• Politis , I , Zhao , X , McBride , BW and Burton , JH . 1992 . Function of bovine mammary macrophages as antigen-presenting cells . Veterinary Immunology and Immunopathology , 30 : 399 – 410 .
   PubMed Web of Science ®Google Scholar
• Prado , ME , Luther , DA , Lewis , MJ , Headrick , IA , Almeida , RA and Oliver , SP . 2008 . Vaccination with Streptococcus uberis adhesion molecule induces antibody responses in bovine serum and colostrum . Annual Proceedings of the National Mastitis Committee , : 232 – 233 .
   Google Scholar
• Pullinger , GD , López-Benavides , M , Coffey , TJ , Williamson , JH , Cursons , RT , Summers , E , Lacy-Hulbert , J , Maiden , MC and Leigh , JA . 2006 . Application of Streptococcus uberis multilocus sequence typing: analysis of the population structure detected among environmental and bovine isolates from New Zealand and the United Kingdom . Applied and Environmental Microbiology , 72 : 1429 – 1436 .
   PubMed Web of Science ®Google Scholar
• Rainard , P . 1986 . Bacteriostatic activity of bovine milk lactoferrin against mastitic bacteria . Veterinary Microbiology , 11 : 387 – 392 .
   PubMed Web of Science ®Google Scholar
• Rainard , P . 2003 . The complement in milk and defence of the bovine mammary gland against infections . Veterinary Research , 34 : 647 – 670 .
   PubMed Web of Science ®Google Scholar
• Riollet , C , Rainard , P and Poutrel , B . 2000 . Cells and cytokines in inflammatory secretions of bovine mammary gland . Advances in Experimental Medicine and Biology , 480 : 247 – 258 .
   PubMed Web of Science ®Google Scholar
• Riollet , C , Rainard , P and Poutrel , B . 2001 . Cell subpopulations and cytokine expression in cow milk in response to chronic Staphylococcus aureus infection . Journal of Dairy Science , 84 : 1077 – 1084 .
   PubMed Web of Science ®Google Scholar
• Rivas , AL , Schwager , SJ , González , RN , Quimby , FW and Anderson , KL . 2007 . Multifactorial relationships between intramammary invasion by Staphylococcus aureus and bovine leukocyte markers . Canadian Journal of Veterinary Research , 71 : 135 – 144 .
   PubMed Web of Science ®Google Scholar
• Schmitt-Van , de and Zadoks , RN . 2007 . Genotypic and phenotypic detection of macrolide and lincosamide resistance in Streptococcus uberis . Journal of Dairy Science , 90 : 5089 – 5096 .
   PubMed Web of Science ®Google Scholar
• Schwertfeger , KL , Rosen , JM and Cohen , DA . 2006 . Mammary gland macrophages: pleiotropic functions in mammary development . Journal of Mammary Gland Biology and Neoplasia , 11 : 229 – 238 .
   PubMed Web of Science ®Google Scholar
• Seegers , H , Fourichon , C and Beaudeau , F . 2003 . Production effects related to mastitis and mastitis economics in dairy cattle herds . Veterinary Research , 34 : 475 – 491 .
   PubMed Web of Science ®Google Scholar
• Shkreta , L , Talbot , BG , Diarra , MS and Lacasse , P . 2004 . Immune responses to a DNA/protein vaccination strategy in dairy cows . Vaccine , 23 : 114 – 126 .
   PubMed Web of Science ®Google Scholar
• Smith , AJ , Ward , PN , Field , TR , Jones , CL , Lincoln , RA and Leigh , JA . 2003 . MtuA, a lipoprotein receptor antigen from Streptococcus uberis, is responsible for acquisition of manganese during growth in milk and is essential for infection of the lactating bovine mammary gland . Infection and Immunity , 71 : 4842 – 4849 .
   PubMed Web of Science ®Google Scholar
• Smith , JL , Hogan , JS and Smith , KL . 1999 . Efficacy of intramammary immunization with an Escherichia coli J5 bacterin . Journal of Dairy Science , 82 : 2582 – 2588 .
   PubMed Web of Science ®Google Scholar
• Sordillo , LM , Kendall , JT , Corl , CM and Cross , TH . 2005 . Molecular characterization of a saposin-like protein family member isolated from bovine lymphocytes . Journal of Dairy Science , 88 : 1378 – 1390 .
   PubMed Web of Science ®Google Scholar
• Takemura , K , Hogan , JS , Lin , J and Smith , KL . 2002 . Efficacy of immunization with ferric citrate receptor FecA from Escherichia coli on induced coliform mastitis . Journal of Dairy Science , 85 : 774 – 781 .
   PubMed Web of Science ®Google Scholar
• Tamilselvam , B , Almeida , RA , Dunlap , JR and Oliver , SP . 2006 . Streptococcus uberis internalizes and persists in bovine mammary epithelial cells . Microbial Pathogenesis , 40 : 279 – 285 .
   PubMed Web of Science ®Google Scholar
• Tatarczuch , L , Philip , C , Bischof , R and Lee , CS . 2000 . Leucocyte phenotypes in involuting and fully involuted mammary glandular tissues and secretions of sheep . Journal of Anatomy , 196 : 313 – 326 .
   PubMed Web of Science ®Google Scholar
• Tatarczuch , L , Bischof , RJ , Philip , CJ and Lee , CS . 2002 . Phagocytic capacity of leucocytes in sheep mammary secretions following weaning . Journal of Anatomy , 201 : 351 – 361 .
   PubMed Web of Science ®Google Scholar
• Taylor , BC , Dellinger , JD , Cullor , JS and Stott , JL . 1994 . Bovine milk lymphocytes display the phenotype of memory T cells and are predominantly CD8+ . Cellular Immunology , 156 : 245 – 253 .
   PubMed Web of Science ®Google Scholar
• Tenhagen , BA , Edinger , D , Baumgartner , B , Kalbe , P , Klunder , G and Heuwieser , W. 2001 . Efficacy of a herd-specific vaccine against Staphylococcus aureus to prevent post-partum mastitis in dairy heifers . Journal of Veterinary Medicine A. Physiology, Pathology, Clinical Medicine , 48 : 601 – 607 .
   PubMedGoogle Scholar
• Thomas , LH , Haider , W , Hill , AW and Cook , RS . 1994 . Pathologic findings of experimentally induced Streptococcus uberis infection in the mammary gland of cows . American Journal of Veterinary Research , 55 : 1723 – 1728 .
   PubMed Web of Science ®Google Scholar
• Tomita , GM , Nickerson , SC , Owens , WE and Wren , B . 1998 . Influence of route of vaccine administration against experimental intramammary infection caused by Escherichia coli . Journal of Dairy Science , 81 : 2159 – 2164 .
   PubMed Web of Science ®Google Scholar
• Ward , PN , Field , TR , Rapier , CD and Leigh , JA . 2003 . The activation of bovine plasminogen by PauA is not required for virulence of Streptococcus uberis . Infection and Immunity , 71 : 7193 – 7196 .
   PubMed Web of Science ®Google Scholar
• Watson , DL . 1984 . Evaluation of attenuated, live staphylococcal mastitis vaccine in lactating heifers . Journal of Dairy Science , 67 : 2608 – 2613 .
   PubMed Web of Science ®Google Scholar
• Watson , DL . 1988 . Vaccination against experimental staphylococcal mastitis in ewes . Research in Veterinary Science , 45 : 16 – 21 .
   PubMed Web of Science ®Google Scholar
• Watson , DL and Kennedy , JW . 1981 . Immunisation against experimental staphylococcal mastitis in sheep - effect of challenge with a heterologous strain of Staphylococcus aureus . Australian Veterinary Journal , 57 : 309 – 313 .
   PubMed Web of Science ®Google Scholar
• Watson , DL and Lee , CG . 1978 . Immunity to experimental staphylococcal mastitis - comparison of live and killed vaccines . Australian Veterinary Journal , 54 : 374 – 378 .
   PubMed Web of Science ®Google Scholar
• Wedlock , DN , Denis , M and Buddle , BM . 2007 . Can Vaccines Offer a Solution to Mastitis? , Wellington, , NZ : Immunet Meeting .
   Google Scholar
• Wedlock , DN , Denis , M , Lacy-Hulbert , SJ and Buddle , BM . 2008 . Interleukin-1β infusion in bovine mammary glands prior to challenge with Streptococcus uberis reduces bacterial growth but causes sterile mastitis . Veterinary Research Communications , 32 : 439 – 447 .
   PubMed Web of Science ®Google Scholar
• Wheeler , TT , Hodgkinson , AJ , Prosser , CG and Davis , SR . 2007 . Immune components of colostrum and milk - A historical perspective . Journal of Mammary Gland Biology and Neoplasia , 12 : 237 – 247 .
   PubMed Web of Science ®Google Scholar
• Williams , JM , Shipley , GR , Smith , GL and Gerber , DL . 1975 . A clinical evaluation of Staphylococcus aureus bacterin in the control of staphylococcal mastitis in cows . Veterinary Medicine, Small Animal Clinician , 70 : 587 – 594 .
   PubMedGoogle Scholar
• Wilson , DJ , Grohn , YT , Bennett , GJ , Gonález , RN , Schukken , YH and Spatz , J . 2008 . Milk production change following clinical mastitis and reproductive performance compared among J5 vaccinated and control dairy cattle . Journal of Dairy Science , 91 : 3869 – 3879 .
   PubMed Web of Science ®Google Scholar
• Woolford , MW , Hook , IJ , Eden , MT , Joe and AK . 1995 . “ The SAMM plan, a seasonal approach to managing mastitis ” . In Proceedings of the Third IDF International Mastitis Seminar Vol. Supplement 4 , 59 – 63 .
   Google Scholar
• Woolford , MW , Williamson , JH , Day , AM and Copeman , PJ . 1998 . The prophylactic effect of a teat sealer on bovine mastitis during the dry period and the following lactation . New Zealand Veterinary Journal , 46 : 12 – 19 .
   PubMed Web of Science ®Google Scholar
• Yancey , RJ . 1993 . Recent advances in bovine vaccine technology . Journal of Dairy Science , 76 : 2418 – 2436 .
   PubMed Web of Science ®Google Scholar
• Yancey , RJ . 1999 . Vaccines and diagnostic methods for bovine mastitis: fact and fiction . Advances in Veterinary Medicine , 41 : 257 – 273 .
   PubMedGoogle Scholar
• Yoshida , K , Ichiman , Y , Narikawa , S and Evans , WB . 1984 . Staphylococcal capsular vaccine for preventing mastitis in two herds in Georgia . Journal of Dairy Science , 67 : 620 – 627 .
   PubMed Web of Science ®Google Scholar