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Scientific Articles

A comparison of two different ketamine and diazepam combinations with an alphaxalone and medetomidine combination for induction of anaesthesia in sheep

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Pages 136-141 | Received 06 Jul 2011, Accepted 11 Nov 2011, Published online: 21 Feb 2012

References

  • Andaluz , A , Felez-Ocaña , N , Santos , L , Fresno , L and García , F . The effects on cardio-respiratory and acid-base variables of the anaesthetic alfaxalone in a 2-hydroxypropyl-β-cyclodextrin (HPCD) formulation in sheep . The Veterinary Journal , doi:10.1016/j.tvjl.2011.03.017, 2011
  • Camburn , M A . 1982 . Use of alphaxalone-alphadolone in ruminants . Veterinary Record , 111 : 166 – 7 .
  • Campbell , D , Forrester , A C , Miller , D C , Hutton , I , Kennedy , J A , Lawrie , T D , Lorimer , A R and McCall , D . 1971 . A preliminary clinical study of CT1341-a steroid anaesthetic agent . British Journal of Anaesthesia , 43 : 314 – 24 .
  • Celly , C S , McDonell , W N , Black , W D and Young , S S . 1997 . Cardiopulmonary effects of clonidine, diazepam and the peripheral alpha 2 adrenoceptor agonist ST-91 in conscious sheep . Journal of Veterinary Pharmacology and Therapeutics , 20 : 472 – 8 .
  • Celly , C S , McDonell , W N and Black , W D . 1999 . Cardiopulmonary effects of the alpha2-adrenoceptor agonists medetomidine and ST-91 in anesthetized sheep . Journal of Pharmacology and Experimental Therapeutics , 289 : 712 – 20 .
  • Chambers , J P . 1989 . Induction of anaesthesia in dogs with alfentanil and propofol . Journal of the Association of Veterinary Anaesthetists , 16 : 14 – 17 .
  • Clarke , R S , Montgomery , S J , Dundee , J W and Bovill , J G . 1971 . Clinical studies of induction agents. XXXIX: CT1341, a new steroid anaesthetic . British Journal of Anaesthesia , 43 : 947 – 52 .
  • Coates , K M and Flood , P . 2001 . Ketamine and its preservative, benzethonium chloride, both inhibit human recombinant alpha7 and alpha4beta2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes . British Journal of Pharmacology , 134 : 871 – 9 .
  • Copland , M D . 1977 . The effects of CT1341, thiopentone and induction- delivery time on the blood gas and acid-base status of lambs delivered by casesarean operation and on the onset of respiration . Australian Veterinary Journal , 53 : 436 – 9 .
  • Ferre , P J , Pasloske , K , Whittem , T , Ranasinghe , M G , Li , Q and Lefebvre , H P . 2006 . Plasma pharmacokinetics of alfaxalone in dogs after an intravenous bolus of Alfaxan-CD RTU . Veterinary Anaesthesia and Analgesia , 33 : 229 – 36 .
  • Franks , N P . 2008 . General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal . Nature Reviews Neuroscience , 9 : 370 – 86 .
  • Green , C J , Knight , J , Precious , S and Simpkin , S . 1981 . Ketamine alone and combined with diazepam or xylazine in laboratory animals: a 10 year experience . Laboratory Animals , 15 : 163 – 70 .
  • Grint , N J , Smith , H E and Senior , J M . 2008 . Clinical evaluation of alfaxalone in cyclodextrin for the induction of anaesthesia in rabbits . Veterinary Record , 163 : 395 – 6 .
  • Hall , L W . 1972 . Althesin in the larger animal . Postgraduate Medical Journal , 48 ( Supplement 2 ) : 55 – 58 .
  • Hohlrieder , M , Brimacombe , J , Eschertzhuber , S , Ulmer , H and Keller , C . 2007 . A study of airway management using the ProSeal LMA laryngeal mask airway compared with the tracheal tube on postoperative analgesia requirements following gynaecological laparoscopic surgery . Anaesthesia , 62 : 913 – 8 .
  • Kastner , S BR , Ohlerth , S , Pospischil , A , Boller , J and Huhtinen , M K . 2007 . Dexmedetomidine-induced pulmonary alterations in sheep . Research in Veterinary Science , 83 : 217 – 26 .
  • Keates , H . 2003 . Induction of anaesthesia in pigs using a new alphaxalone formulation . Veterinary Record , 153 : 627 – 8 .
  • Kelland , M D , Soltis , R P , Boldry , R C and Walters , J R . 1993 . Behavioral and electrophysiological comparison of ketamine with dizocilpine in the rat . Physiology and Behavior , 54 : 547 – 54 .
  • Ko , J CH and McGrath , C J . 1995 . Effects of atipamezole and yohimbine on medetomidine-induced central nervous system depression and cardiorespiratory changes in lambs . American Journal of Veterinary Research , 56 : 629 – 32 .
  • Lawrence , C , Prinzen , F and de Lange , S . 1996 . The effect of dexmedetomidine on nutrient organ blood flow . Anesthesia and Analgesia , 83 : 1160 – 5 .
  • Maddern , K , Adams , V J , Hill , N A and Leece , E A . 2010 . Alfaxalone induction dose following administration of medetomidine and butorphanol in the dog . Veterinary Anaesthesia and Analgesia , 37 : 7 – 13 .
  • Marsh , M K , McLeod , S R , Hansen , A and Maloney , S K . 2009 . Induction of anaesthesia in wild rabbits using a new alfaxalone formulation . Veterinary Record , 164 : 122 – 3 .
  • Muge , D K , Chambers , J P , Livingston , A and Waterman , A E . 1994 . Analgesic effects of medetomidine in sheep . Veterinary Record , 135 : 43 – 44 .
  • Murrell , J C and Hellebrekers , L J . 2005 . Medetomidine and dexmedetomidine: a review of cardiovascular effects and antinociceptive properties in the dog . Veterinary Anaesthesia and Analgesia , 32 : 117 – 27 .
  • Powell , H , Morgan , M and Sear , J W . 1992 . Pregnanolone: a new steroid intravenous anaesthetic. Dose-finding study . Anaesthesia , 47 : 287 – 90 .
  • Raheim , B , Amemo , J M and Stuen , S . 2000 . Medetomidine and atipamezole in sheep: disposition and clinical effects . Journal of Veterinary Pharmacology and Therapeutics , 23 : 401 – 4 .
  • Scheinin , M and Schwinn , D . 1992 . The locus coeruleus: site of hypnotic actions of alpha2-adrenoreceptor agonists? . Anaesthesiology , 76 : 873 – 5 .
  • Sewell , J C and Sear , J W . 2002 . Can molecular similarity-activity models for intravenous general anaesthetics help explain their mechanism of action? . British Journal of Anaesthesia , 88 : 166 – 74 .
  • Visser , S A , Smulders , C J , Reijers , B P , Van der Graaf , P H , Peletier , L A and Danhof , M . 2002 . Mechanism-based pharmacokinetic-pharmacodynamic modeling of concentration-dependent hysteresis and biphasic electroencephalogram effects of alphaxalone in rats . Journal of Pharmacology and Experimental Therapeutics , 302 : 1158 – 67 .
  • Waterman , A E . 1981 . Evaluation of the actions and use of alphaxolone/alphadolone (CT1341) in sheep . Research in Veterinary Science , 30 : 114 – 9 .
  • Waterman , A and Livingston , A . 1978 . Some physiological effects of ketamine in sheep . Research in Veterinary Science , 25 : 225 – 33 .

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