Detection of hypoglycin A in the seeds of sycamore (Acer pseudoplatanus) and box elder (A. negundo) in New Zealand; the toxin associated with cases of equine atypical myopathy

References

• *Anonymous. New Zealand virtual herbarium 2011. http://virtualherbarium.org.nz/map49 (accessed 09 February 2015). New Zealand National Herbarium Network, Manaaki Whenua, Landcare Research New Zealand Ltd, Lincoln, New Zealand, 2011
   Google Scholar
• *Anonymous. Quarterly review of diagnostic cases April to June. Surveillance 40 (3), 44–57, 2013
   Google Scholar
• *Anonymous. Climate summary for January 2014. https://www.niwa.co.nz/climate/summaries/monthly/climate-summary-for-january-2014 (accessed 20 March 2015). National Institure of Water and Atmospheric Research, Auckland New Zealand, 2015
   Google Scholar
• Baise E, Habyarimana JA, Amory H, Boemer F, Douny C, Gustin P, Marcillaud-Pitel C, Patarin F, Weber M and Votion DM. Samaras and seedlings of Acer pseudoplatanus are potential sources of hypoglycin A intoxication in atypical myopathy without necessarily inducing clinical signs. Equine Veterinary Journal, doi: 10.1111/evj.12499, 2015
   PubMed Web of Science ®Google Scholar
• Bochnia M, Ziegler J, Sander J, Uhlig A, Schaefer S, Vollstedt S, Glatter M, Abel S, Recknagel S, Schusser GF, et al. Hypoglycin A content in blood and urine discriminates horses with atypical myopathy from clinically normal horses grazing on the same pasture. PLoS ONE 10, e0136785, 2015
   PubMed Web of Science ®Google Scholar
• Boemer F, Deberg M, Schoos R, Baise E, Amory H, Gault G, Carlier J, Gaillard Y, Marcillaud-Pitel C, Votion D. Quantification of hypoglycin A in serum using aTRAQ® assay. Journal of Chromatography B 997, 75–80, 2015
   PubMed Web of Science ®Google Scholar
• Bowen JN, Craig JF. Myoglobinuria in horses. Veterinary Record 35, 354–5, 1942
   Google Scholar
• Chace DH, Kalas TA, Naylor EW. Use of tandem mass spectrometry for multianalyte screening of dried blood specimens from newborns. Clinical Chemistry. 49, 1797–817, 2003
   PubMed Web of Science ®Google Scholar
• Finno CJ, Valberg SJ, Wunschmann A, Murphy MJ. Seasonal pasture myopathy in horses in the midwestern United States: 14 cases (1998–2005). Journal of the American Veterinary Medical Association 229, 1134–41, 2006
   PubMed Web of Science ®Google Scholar
• Fowden L, Pratt HM. Cyclopropylamino acids of the genus Acer: distribution and biosynthesis. Phytochemistry 12, 1677–81, 1973
   Web of Science ®Google Scholar
• Gillman JH, Hegeman AD and Sharp RG. Clarifying the role of maples in atypical myopathy. Equine Veterinary Journal 46, 135–6, 2014
   PubMed Web of Science ®Google Scholar
• *Habyarimana JA, Baise E, Weber M, Franck T, Gault G, Carlier J, Votion D, Gustin P. Validation of HPTLC method for quantitative determination of hypoglycin A in methanolic extracts of maple (Acer) samples. Proceedings of the International Symposium for Thin-Layer Chromatography, Lyon, France. P 185, 2014
   Google Scholar
• *Hill FI, Martin V. Idiopathic myolysis in a group of horses. Equine Veterinary Practitioner 33, 23–8, 2009
   Google Scholar
• *Howell C. Consolidated list of environmental weeds in New Zealand DOC Research and Development Series 292 http://www.doc.govt.nz/upload/documents/science-and-technical/drds292.pdf (accessed 30 October 2015). Department of Conservation, Wellington, New Zealand, 2008
   Google Scholar
• Irwin CFP, Pulsford MF. Enzootic myoglobinuria in a horse. Australian Veterinary Journal 27, 101–2, 1951
   PubMedGoogle Scholar
• McKenzie RK, Gibson IR, Ritmeester A. Three cases of a presumptive atypical myopathy in New Zealand horses. New Zealand Veterinary Journal 61, 367–72, 2013
   PubMed Web of Science ®Google Scholar
• Sponseller BT, Valberg SJ, Schultz NE, Bedford H, Wong DM, Kersh K, Shelton GD. Equine multiple Acyl-CoA dehydrogenase deficiency (MADD) associated with seasonal pasture myopathy in the midwestern United States. Journal of Veterinary Internal Medicine 26, 1012–8, 2012
   PubMed Web of Science ®Google Scholar
• Unger L, Nicholson A, Jewitt EM, Gerber V, Hegeman A, Sweetman L, Valberg S. Hypoglycin A concentrations in seeds of Acer Psuedoplatanus trees growing on atypical myopathy-affected and control pastures. Journal of Veterinary Internal Medicine 28, 1289–93, 2014
   PubMed Web of Science ®Google Scholar
• Valberg SJ, Sponseller BT, Hegeman AD, Earing J, Bender JB, Martinson KL, Patterson SE, Sweetman L. Seasonal pasture myopathy/atypical myopathy in North America associated with ingestion of hypoglycin a within seeds of the box elder tree. Equine Veterinary Journal 45, 419–26, 2013
   PubMed Web of Science ®Google Scholar
• van Galen G, Marcillaud PC, Saegerman C, Patarin F, Amory H, Baily JD, Cassart D, Gerber V, Hahn C, Harris P, et al. European outbreaks of atypical myopathy in grazing equids (2006–2009): spatiotemporal distribution, history and clinical features. Equine Veterinary Journal 44, 614–20, 2012
   PubMed Web of Science ®Google Scholar
• Votion DM, Serteyn D. Equine atypical myopathy: a review. The Veterinary Journal 178, 185–90, 2008
   PubMed Web of Science ®Google Scholar
• Votion DM, van Galen G, Sweetman L, Boemer F, de Tullio P, Dopagne C, Lefere L, Mouithys-Mickalad A, Patarin F, Rouxhet S, et al. Identification of methylenecyclopropyl acetic acid in serum of European horses with atypical myopathy. Equine Veterinary Journal 46, 146–9, 2014
   PubMed Web of Science ®Google Scholar
• Westermann CM, Dorland L, Votion DM, de Sain-van der Velden MG, Wijnberg ID, Wanders RJ, Spliet WG, Testerink N, Berger R, Ruiter JP, et al. Acquired multiple Acyl-CoA dehydrogenase deficiency in 10 horses with atypical myopathy. Neuromuscular Disorders 18, 355–64. 2008
   PubMed Web of Science ®Google Scholar