Bioactivation to free radicals and cytotoxicity of 1,1-dichloro-1-fluoroethane (HCFC-141b)

References

• ALBANO, E., TOMASI, A., CHEESEMAN, C. K., VANNINI, V. and DIANZANI, M. U., 1985, Use of isolated hepatocytes for the detection of free radical intermediates of halogenated hydrocarbons. In G. Poli, K. H. Cheeseman, M. U. Dianzani and T. F. Slater (eds), Free Radicals in Liver Injury (Oxford: IRL), pp. 7–16.
   Google Scholar
• ANDERS, M. W. and DEKANT W., 1994, Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Compounds (San Diego: Academic Press).
   Google Scholar
• BROCK, W. J., TROCHIMOWICZ, H. J., MILLISCHER, R. J., FARR, C., KAWANO, T. and RUSCH, G. M., 1995, Acute and subchronic toxicity of 1,1-dichloro-1-fluoroethane (HCFC-141b). Food and Chemical Toxicology, 33, 483–490.
   PubMed Web of Science ®Google Scholar
• COOPER, D. Y., CANNON, M. D., SCHEYER, H., NOVACK, B. G. and ROSENTHAL, O., 1982, Anaerobic technique for spectrometric studies of oxidative enzymes with low oxidation-reduction potentials. In J. B. Schenkman and D. Kupfer (eds), Hepatic Cytochronw P-450 Monoxygenaw System (Oxford: Pergamon), pp. 813–832.
   Google Scholar
• CORONGIU, F. P., POLI, G., DIANZANI, M. U., CHEESEMAN, K. H. and SLATER, T. F., 1986. Lipid peroxidation and molecular damage to polyunsaturated fatty acids in rat liver. Recognition of two classes of hydroperoxides formed under conditions in vivo. Chemico-Biological Interactions, 59, 147–155.
   PubMed Web of Science ®Google Scholar
• DEKANT, W., 1996, Toxicology of chlorofluorocarbon replacements. Environmental Health Perspectives, 104 (suppl. 1), 75–83.
   PubMedGoogle Scholar
• ECETOC, 1994. Joint Assessment of Commodity Chemicals No. 29. 1,1-Dichloro-1-fluoroethane (HCFC-141b) CAS No 1717–6 (Brussels: ECETOC).
   Google Scholar
• FERRARA, R., TOLANDO, R., KING, L. J. and MANNO, M., 1997, Cytochrome P450 inactivation during reductive metabolism of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) by phenobarbital- and pyridine-induced rat liver microsomes. Toxicology and Applied Pharmacology, 143, 420–428.
   PubMed Web of Science ®Google Scholar
• FERRARA, R., TOLANDO, R., ZANOVELLO, A., TOMASI, A. and MANNO, M., 1999, Reductive bioactivation of HCFC-141b to free radical intermediates by rat liver microsomal cytochrome P-450. Toxicologist, 48, 221.
   Google Scholar
• GRIFFITH, O. W., 1995, Glutathione and glutathione disulfide. In H. U. Bergmeyler (ed.), Methods of Enzymatic Analysis (Berlin: Chemie), pp. 521–529.
   Google Scholar
• HARRIS, J. W., POHL L. R., MARTIN, J. L. and ANDERS, M. W., 1991, Tissue acylation by the chlorofluorocarbon substitute 2,2 -dichloro-1,1,1-trifluoroethane. Proceedings of the National Academy of Sciences, USA, 88, 1407–1410.
   Google Scholar
• HALLIWELL, B. and GUTTERIDGE, J. M. C., 1989, Lipid peroxidation: a radical chain reaction. In B. Halliwell and J. M. C. Gutteridge (eds), Free Radicals in Biology and Medicine (Oxford: Clarendon), pp. 188–276.
   Google Scholar
• HUWYLER, J., AESCHLIMANN, D., CHRISTEN, U. and GUT, J., 1992, The kidney as a novel target tissue for protein adduct formation associated metabolism of halotane and the candidate chlorofluorocarb on replacement 2,2 -dichloro-1,1,1-trifluoroethane. European Journal of Biochemistry, 207, 229–238.
   PubMedGoogle Scholar
• JARABEK, A. M., FISCHER, J. W., RUBENSTEIN, R., LIPSCOMB, J. C., WILLIAMS, R. J., VINEGAR, A. and McDouGAL, J. N., 1994, Mechanistic insights aid the search for CFC substitutes : risk assessment of HCFC-123 as an example. Risk Analysis, 14, 231-25 O.
   Google Scholar
• KAMATH, S. A., KUMMEROW, F. A. and NARAYAN, K. A., 1971, A simple procedure for the isolation of rat liver microsomes. FEBS Letters, 17, 90–92.
   PubMed Web of Science ®Google Scholar
• KAPPUS, H., 1991, Biochemical mechanisms of chemical-induced lipid peroxidation. In C. Vigo-Pelfrey (ed.), Membrane Lipid Oxidation (Boca Raton: CRC Press), pp. 103–119.
   Google Scholar
• LIND, R. C. and GANDOLFI, A. J., 1993, Concentration-dependent inhibition of halotane bio-transformation in the guinea pig. Drug Metabolism and Disposition, 21, 386–389.
   PubMedGoogle Scholar
• LIND, R. C., GANDOLFI, A. J. and HALL, P. M., 1995, Biotransformation and hepatotoxicity of HCFC-123 in the guinea pig: potentiation of hepatic injury by prior glutathione depletion. Toxicology and Applied Pharmacology, 134, 175–181.
   PubMed Web of Science ®Google Scholar
• Loizou, G. D. and ANDERS, M. W., 1993, Gas-uptake pharmacokinetics and biotransformation of 1,1-dichloro-1-fluororthane (HCFC-141b). Drug Metabolism and Disposition, 21, 634–639.
   PubMed Web of Science ®Google Scholar
• LONGSTRETH, J., 1988, Cutaneous malignant melanoma and ultraviolet radiation. A review. Cancer Metastasis Reviews, 7, 321–333.
   PubMed Web of Science ®Google Scholar
• MANNO, M., CAZZARO, S. and REZZADORE, M., 1991, The mechanism of the suicidal reductive inactivation of microsomal cytochrome P-450 by halothane. Archives of Toxicology, 65, 191–198.
   PubMed Web of Science ®Google Scholar
• MANNO, M., DE MATTEIS, F. and KING, L. J., 1988, The mechanism of the suicidal, reductive inactivation of microsomal cytochrome P-450 by carbon tetrachloride. Biochemical Pharmacology, 37, 1981–1990.
   PubMed Web of Science ®Google Scholar
• MANNO, M., FERRARA, R., ZANOVELLO, A., BORTOLATO, S. and TOLANDO, R., 1999, Cytotoxicity of HCFC-123 in isolated rat hepatocytes. Toxicologist, 48, 94.
   Google Scholar
• MANNO, M., ZANOVELLO, A., FERRARA, R. and TOLANDO, T., 1998, Dose- and time-dependent cytotoxicity of HCFC-12 3 and HCFC-141b on isolated rat hepatocytes under aerobic and hypoxic conditions. Toxicology Letters, 95 (suppl. 1), 162–163.
   Google Scholar
• MOLINA, M. J. and ROWLAND, F. S., 1974, Stratospheric sink for chlorofluoromethanes : chlorine atom-catalysed destruction of ozone. Nature, 249, 810–815.
   Web of Science ®Google Scholar
• RUSH, R. J., KLAUNIG, J. E., SCHULTZ, N. E., ASKARI, A. B., LACHER, D. A., PEPEIRA, M. A. and GOLDBLATT, P. J., 1986, Mechanism of chloroform and carbon tetrachloride toxicity in primary cultured mouse hepatocytes. Environmental Health Perspectives, 69, 301–305.
   PubMedGoogle Scholar
• TAYLOR, H. R., WEST, S. K., ROSENTHAL, F. S., MUNOZ, B., NEWLAND, H. S., ABBEY, H. and EMMETT, E. A., 1988, Effect of ultraviolet radiation on cataract formation. New England Journal of Medicine, 319, 1429–1433.
   PubMed Web of Science ®Google Scholar
• TOLANDO, R., FERRARA, R., ELDIRDIRI, N. I., ALBORES, A., KING L. J. and MANNO, M., 1996, Reductive activation of 1,1,-dichloro-1-fluoroethane (HCFC-141b) by phenobarbital- and pyridine-induced rat liver microsomal cytochrome P450. Xenobiotka, 26, 425435.
   Google Scholar
• TOMASI, A., BILLING, S., GARNER, A., SLATER, T. F. and ALBANO, E., 1983, The metabolism of halothane by hepatocytes: a comparison between free radical spin-trapping and lipid peroxidation in relation to cell damage. Chemko-Biological Interactions, 46, 353–368.
   PubMed Web of Science ®Google Scholar
• TONG, Z., UTELL, M. J., MORROW, P. E., RUSCH, G. M. and ANDERS, M. W., 1998, Metabolism of 1,1 - dichloro-1-fluoroethane (HCFC-141b) in human volunteers. Drug Metabolism and Disposition, 26, 711–713.
   PubMed Web of Science ®Google Scholar
• WILLS, E. D., 1987, Evaluation of lipid peroxidation in lipids and biological membranes. In K. Snell and B. Mullock (eds), Biochemical Toxicology (Oxford: IRL) pp. 127–152.
   Google Scholar
• WILLIAMS, G. M., BERMUDEZ E. and SCAMUZZINO D., 1977, Rat hepatocyte primary cell cultures. In Vitro, 13, 809–817.
   Google Scholar
• ZANOVELLO, A., FERRARA, R., TOMASI, A., WHITE, I. N. H. and MANNO, M., 1999, Effect of P450 inhibitors on the bioactivation and cytotoxicity of HCFC-123 and HCFC-141b in isolated rat hepatocytes. Proceedings of the International Conference on In Vitro Cytotoxicity Mechanisms, 25–27 January, Rome, Abstract book, p. 68.
   Google Scholar