References
- DOIC, M. V. and CLARE, R. A., 1991, Use of thermospray liquid chromatography-mass spectrometry to aid in the identification of urinary metabolites of a novel antiepileptic drug, Lamotrigine. Journal of Chromatography, 554, 181–189.
- DEAR, G. J., AYRTON, J., PLUMB, R., SWEATMAN, B. C. and IsmAIL, I. M., 1999, Tandem mass spectrometry linked fraction collection for the isolation of drug metabolites from biological matrices. Rapid Communications in Mass Spectrometry, 13, 886–894.
- DEAR, G. J., IsmAIL, I., MUTCH, P. J., DAVIES, L. H., PLUMB, R. and SWEATMAN, B. C., 2000, Urinary metabolites of a novel non-nucleoside reverse transcriptase inhibitor in rabbit, mouse and human: identification of fluorine NIH shift metabolites using NMR and tandem MS. Xenobiotica, 30, 407–426.
- DELBRESSINE, L. P. C., MOONEN, M. E. G., KASPERSEN, F. M., JAcoas, P. L. and WAGENAARS, G. L., 1992, Biotransformations of mianserin in laboratory animals and man. Xenobiotica, 22, 227–236.
- ISMAIL, I., DEAR, G. J., MUTCH, P. J., DAVIES, L. H., PLUMB R. and SWEATMAN, B. C., 1999, The urinary metabolism of the novel non-nucleoside reverse transcriptase inhibitor GW420867X in dog, Cynomolgus monkey and mini-pig. Xenobiotica, 29, 957–967.
- LEVY, G. C. and LICHTER, R. L., 1979, Nitrogen-15 Nuclear Magnetic Resonance Spectroscopy (Chichester: Wiley-Inters cience).
- MARTIN, G. J., MARTIN, M. V. and GOUESNARD, J. P., 1981,15N-NMR Spectroscopy (Berlin: Springer-Verlag).
- MALET-MARTINO, M. C. and MARTINO, R., 1989, The application of nuclear magnetic resonance spectroscopy to drug metabolism studies. Xenobiotica, 19, 583–607.
- PLUMB, R., DEAR, G. J., AYRTON, J., SWEATMAN, B. C. and IsmAIL, I. M., 1999, The use of preparative HPLC with tandem mass spectrometric directed fraction collection for the isolation and characterisation of drug metabolites in urine by NMR and LC/MS. Rapid Communications in Mass Spectrometry, 13, 845–854.
- SAKAMOTO, K. and NAKAMURA, Y., 1993, Urinary metabolites of pinacidil. II. Species differences in the metabolism of pinacidil. Xenobiotica, 23, 649–656.
- SCARFE, G. B., WRIGHT, B., CLAYTON, E., TAYLOR, S., WILSON, I. D., LINDON, J. C. and NICHOLSON, J. K., 1998,19F-NMR and directly coupled HPLC-NMR-MS investigations into the metabolism of 2-bromo-4-trifluoromethylaniline in rat: urinary excretion balance study without the use of radiolabelling. Xenobiotica, 28, 373–388.
- STONEHOUSE, J., ADELL, P., KEELER, J. and SHAKA, A. J., 1994, Ultra high-quality NOE Spectra, Journal of the American Chemical Society, 116, 6037.
- THOMAS, R. C. and I-IARPOOTLIAN, H., 1975, Metabolism of minoxidil, a new hypotensive agent II: Biotransformation following oral administration to rats, dogs and monkeys. Journal of Pharmaceutical Sciences, 64, 1366–1371.
- WADE, K. E., TROKE, J., MACDONALD, C. M., WILSON, I. D. and NICHOLSON J. K., 1988, 19F studies of the metabolism of trifluoro-methylaniline. In E. Reid, J. D. Robinson and I. D. Wilson (eds), Bioanalysis of Drugs and Metabolites (London: Plenum), pp. 383–387.