Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 32, 2002 - Issue 12
43
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Decreased hepatobiliary transport of methotrexate in adjuvant arthritis rats

, , &
Pages 1151-1160 | Published online: 22 Sep 2008

References

  • BELPAIRE, M. F., DE SMET, F., CHINDAVIJAK, B., FRAEYMAN, N. and BOGAERT, G. M., 1989, Effect of turpentine-induced inflammation on the disposition kinetics of propranolol, metoprolol and antipyrine in the rat. Fundamentals in Clinical Pharmacology, 3, 79–88.
  • BISHOP, H., SCHNEIDER, E. R. and WELLING, P., 1981, Plasma propranolol concentrations in rats with adjuvant-induced arthritis. Biopharmacology and Drug Disposition, 2, 291–297.
  • BOOTH, L. C., BROUWER, R. K. and BROUWER, L. R. K., 1998, Effect of multidrug resistance modulators on the hepatobiliary disposition of doxorubicin in the isolated perfused rat liver. Cancer Research, 58, 3641–3648.
  • BUCHAR, E. and JANKU, I., 1985, The effect of adjuvant-induced arthritis on rat liver microsomal phospholipid metabolism. Methods and Findings in Experimental and Clinical Pharmacology, 7, 469–472.
  • DIPASQUALE, G., WELAJ, P. and RASSAERT, L. C., 1974, Prolonged pentobarbital sleeping time in adjuvant-induced polyarthritic rats. Research Communications in Chemical Pathology and Pharmacology, 9, 253–264.
  • HARRIS, E. D., 1981, Rheumatoid arthritis; the clinical spectrum. In Textbook of Rheumatology (Philadelphia: W. B. Saunders), pp. 928–963.
  • HE, L. Y., TANIGAWARA, Y., YASUHARA, M. and HORI, R., 1991, Effect of folinic acid On tissue residence and excretion of methotrexate in rats. Drug Metabolism and Disposition, 19, 729–734.
  • HONSCHA, W. and PETZINGER, E., 1999, Characterization of the bile acid sensitive methotrexate carrier of rat liver cells. Naunyn-Schmiedeberg's Archives in Pharmacology, 359, 411–419.
  • LIN, J. H., SUGIYAMA, Y., AWAZU, S. and HANANO, M., 1982, In vitro and in vivo evaluation of the tissue-to-blood partition coefficient for physiological pharmacokinetic models. Journal in Pharmacokinetics and Biopharmacology, 10, 637–647.
  • MASUDA, M., PIZUKA, Y., YAMAZAKI, M., NISHIGAKI, R., KATO, Y., NeINUMA, K., SUZUKI, H. and SUGIYAMA, Y., 1997, Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats. Cancer Research, 57, 3506–3510.
  • MEUNIER, J. C. and VERBEECK, K. R., 1999, Glucuronidation of R- and S-ketoprofen, acetoaminophen, and diflunisal by liver microsomes of adjuvant-induced arthritic rats. Drug Metabolism and Disposition, 27, 26–31.
  • MURATA, M., TAMAI, I., SAL, Y., NAGATA, O., KATO, H., SUGIYAMA, Y. and TSUJI, A., 1998, Hepatobiliary transport kinetics of HSR-903, a new quinolone antibacterial agent. Drug Metabolism and Disposition, 26, 1113–1119.
  • NAKAMURA, J., NISHIDA, T., HAYASHI, K., KAWADA, N., UESHIMA, S., SUGIYAMA, Y., ITo, T., SOBUE, K. and MATSUDA, H., 1999, Kupffer cell-mediated down regulation of rat hepatic CMOAT/MRP2 gene expression. Biochemistry and Biophysics Research Communications, 255, 143–149.
  • PHILIPPE, L., GEGOUT-POTTIE, P., GUINGAMP, C., BORDJI, K., TERLAIN, B., NETTER, P. and GILLET, P., 1997, Relations between functional, inflammatory, and degenerative parameters during adjuvant arthritis in rats. American journal of Physiology, 273, R1550—R1556.
  • PIQUETTE-MILLER, M. and JAMALI, F. 1992, Effect of adjuvant arthritis on the disposition of acebutolol enantiomer in rats. Agent Actions, 37, 290–296.
  • PIQUETTE-MILLER, M. and JAMALI, F., 1993, Selective effect of adjuvant arthritis on the disposition of propranolol enantiomer in rats detected using a stereospecific HPLC assay. Pharmaceutical Research, 19, 294–299.
  • SCHNEIDER, R. E., BISHOP, H. and HAWKINS, C. F., 1979, Plasma propranolol concentrations and the erythrocyte sedimentation rate. British journal of Clinical Pharmacology, 8, 43–47.
  • SHIBATA, N., SHIMAKAWA, H., MINOUCHI, T. and YAMAJI, A., 1993, Pharmacokinetics of cyclosporin A after intravenous administration to rats in various disease states. Biological and Pharmacological Bulletin, 16, 1130–1135.
  • TODA, A., Isfm, N., KIHARA, T., NAGAMATSU, A. and SHIMENO, H., 1994, Effects of adjuvant-induced arthritis on hepatic drug metabolism in rats. Xenobiotica, 24, 603–611.
  • TODA, A., KIHARA, T., ONO, N., NAGAMASU, A. and SHIMENO, H., 1996, Liver haem metabolism in adjuvant-induced arthritis rats. Xenobiotica, 26, 415–423.
  • TRACY, T. S., WORSTER, T., BRADLEY, J. D., GREENE, P. K. and BRATER, D. C., 1994, Methotrexate disposition following concomitant administration of ketoprofen, piroxicam and flurbiprofen in patients with rheumatoid arthritis. British Journal of Clinical Pharmacology, 37,453–456.
  • VOS, T. A., HOOIVED, G. J. E., KONING, H., CHILDS, S., MEIJER, D. K. F., MOSHAGE, H., JANSEN, P. L. M. and MULLER, M., 1998, Up-regulation of the multidrug resistance genes, mrpl and mdrlb, and down-regulation of the organic anion transporter, mrp2, and the bile salt transporter, spgp, in endotoxemic rat liver. Hepatology, 28, 1637–1644.
  • WILLIAMS, R. O., FELDMANN, M. and MAINI, N. R., 1992, Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proceedings of the National Academy of Sciences, USA, 89, 9784–9788.
  • YASUHARA, M., FUJIWARA, J., KITADE, S., KATAYAMA, H., OKUMURA, K. and HORI, R., 1985, Effect of altered plasma protein on pharmacokinetics and pharmacodynamics of propranolol in rats after surgery. Journal of Pharmacology and Experimental Therapeutics, 235,513–520.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.