Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 33, 2003 - Issue 2
255
Views
38
CrossRef citations to date
0
Altmetric
Research Article

Time-dependent transcriptional induction of CYP1A1, CYP1A2 and CYP1B1 mRNAs by H+/K+-ATPase inhibitors and other xenobiotics

, , &
Pages 107-118 | Published online: 22 Sep 2008

References

  • BOWEN, W. P., CAREY, J. E., MIAH, A., MCMURRAY, H. F., MUNDAY, P. W., JAMES, R. S., COLEMAN, R. A. and BROWN, A. M., 2000, Measurement of cytochrome P450 gene induction in human hepatocytes using quantitative real-time reverse transcriptase-polymerase chain reaction. Drug Metabolism and Disposition, 28, 781–788.
  • CHIAROLINI, A., DONATO, M. T., GömEz-LEcHóN, M. J., PALA, M., VALERIO, F. and FERRO, M., 1997, Comparison of rat hepatocyte and differentiated hepatoma cell line cultures as bio-indicators of CYP 1A1 inducers in urban air. Biomarkers, 2, 279–285.
  • CURI-PEDROSA, R., DAUJAT, M., PICHARD, L., OURLIN, J. C., CLAIR, P., GERVOT, L., LESCA, P., DOMERGUE, J., JoyEux, H. and FOURTANIER, G., 1994, Omeprazole and lansoprazole are mixed inducers of CYP1A and CYP3A in human hepatocytes in primary culture. Journal of Pharmacology and Experimental Therapeutics, 269, 384–392.
  • DAUJAT, M., CHARRASSE, S., FABRE, I., LESCA, P., JOUNAIDI, Y., LARROQUE, C., POELLINGER, L. and MAUREL, P., 1996, Induction of CYP1A1 gene by benzimidazole derivatives during Caco-2 cell differentiation. Evidence for an aryl-hydrocarbon receptor-mediated mechanism. European Journal of Biochemistry, 237, 642–652.
  • DELESCLUSE, C., LEMAIRE, G., DE SOUSA, G. and RAHMANI, R., 2000, Is CYP1A1 induction always related to AHR signaling pathway? Toxicology, 153, 73–82.
  • DIAZ, D., FABRE, I., DAUJAT, M., SAINT AUBERT, B., BORIES, P., MICHEL, H. and MAUREL, P., 1990, Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450. Gastroenterology, 99, 737–747.
  • DOGRA, S. C., WHITELAW, M. L. and MAY, B. K., 1998, Transcriptional activation of cytochrome P450 genes by different classes of chemical inducers. Clinical and Experimental Pharmacology and Physiology, 25, 1–9.
  • FONTAINE, F., DELESCLUSE, C., DE SOUSA, G., LESCA, P. and RAHMANI, R., 1999, Cytochrome 1A1 induction by primaquine in human hepatocytes and HepG2 cells: absence of binding to the aryl hydrocarbon receptor. Biochemical Pharmacology, 57, 255–262.
  • FROTSCHL, R., CHICHMANOV, L., KLEEBERG, U., HILDEBRANDT, A. G., ROOTS, I. and BROCKMOLLER, J., 1998, Prediction of aryl hydrocarbon receptor-mediated enzyme induction of drugs and chemicals by mRNA quantification. Chemical Research in Toxicology, 11, 1447–1452.
  • HAKKOLA, J., PASANEN, M., PELKONEN, o., HUKKANEN, J., EVISALMI, S., ANTTILA, S., RANE, A., MANTYLA, M., PURKUNEN, R., SAARIKOSKI, S., TOOMING, M. and RAUNIO, H., 1997, Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells. Carcinogenesis, 18, 391–397.
  • KLEEBERG, U., FROTSCHL, R., KRUSEKOPF, S., BROCKMOLLER, J., ROOTS, I., RUCKPAUL, K. and HILDEBRANDT, A. G., 1999, Induction of CYP1A by various benzimidazoles and its significance in administrative drug regulation. Drug Metabolism Reviews, 31, 381–392.
  • KRESS, S. and GREENLEE, W. F., 1997, Cell-specific regulation of human CYP1A1 and CYP1B1 genes. Cancer Research, 57, 1264–1269.
  • KRUSEKOPF, S., KLEEBERG, U., HILDEBRANDT, A. G. and RUCKPAUL, K., 1997, Effects of benzimidazole derivatives on cytochrome P450 1A1 expression in a human hepatoma cell line. Xenobiotica, 27, 1–9.
  • LECLUYSE, E., MADAN, A., HAMILTON, G., CARROLL, K., DEHAAN, R. and PARKINSON, A., 2000, Expression and regulation of cytochrome P450 enzymes in primary cultures of human hepatocytes. Journal of Biochemical and Molecular Toxicology, 14, 177–188.
  • LEKAS, P., TIN, K. L., LEE, C. and PROKIPCAK, R. D., 2000, The human cytochrome P450 1A1 mRNA is rapidly degraded in HepG2 cells. Archives of Biochemistry and Biophysics, 384, 311–318.
  • Lu, C. and Li, A. P., 2001, Species comparison in P450 induction: effects of dexamethasone, omeprazole, and rifampin on P450 isoforms 1A and 3A in primary cultured hepatocytes from man, Sprague-Dawley rat, minipig, and beagle dog. Chemico-Biological Interactions, 134, 271–281.
  • MA, Q. and BALDWIN, K. T., 2002, A cycloheximide-sensitive factor regulates TCDD-induced degradation of the aryl hydrocarbon receptor. Chemosphere, 46, 1491–1500.
  • MA, Q., RENZELLI, A. J., BALDWIN, K. T. and ANTONINI, J. M., 2000, Superinduction of CYP1A1 gene expression. Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide. Journal of Biological Chemistry, 275, 12676–12683.
  • MASUBUCHI, N., Li, A. P. and OKAZAKI, o., 1998, An evaluation of the cytochrome P450 induction potential of pantoprazole in primary human hepatocytes. Chemico-Biological Interactions, 114, 1–13.
  • POSTLIND, H., Vu, T. P., TUKEY, R. H. and QUATTROCHI, L. C., 1993, Response of human CYP1-luciferase plasmids to 2,3,7,8-tetrachlorodibenzo-p-dioxin and polycyclic aromatic hydro-carbons. Toxicology and Applied Pharmacology, 118, 255–262.
  • RODRIGUEZ-ANTONA, C., DONATO, M. T., PAREJA, E., GOMEZ-LECHON, M. J. and CASTELL, J. V., 2001, Cytochrome P-450 mRNA expression in human liver and its relationship with enzyme activity. Archives of Biochemistry and Biophysics, 393, 308–315.
  • ROST, K. L., BROSICKE, H., HEINEMEYER, G. and ROOTS, I., 1994, Specific and dose-dependent enzyme induction by omeprazole in human beings. Hepatology, 20, 1204–1212
  • RUNGE, D., KOHLER, C., KOSTRUBSKY, V. E., JAGER, D., LEHMANN, T., RUNGE, D. M., MAY, U., STOLZ, D. B., STROM, S. C., FLEIG, W. E. and MICHALOPOULOS, G. K., 2000, Induction of cytochrome P450, CYP1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance, MDR-1, and multidrug resistance associated protein, MRP-1, by prototypical inducers in human hepatocytes. Biochemical and Biophysical Research Communications, 273, 333–341.
  • SHEHIN, S. E., STEPHENSON, R. o. and GREENLEE, W. F., 2000, Transcriptional regulation of the human CYP1B1 gene. Evidence for involvement of an aryl hydrocarbon receptor response element in constitutive expression. Journal of Biological Chemistry, 275, 6770–6776.
  • SHIH, H., PICKWELL, G. V., GUENETTE, D. K., BILIR, B. and QUATTROCHI, L. C., 1999, Species differences in hepatocyte induction of CYP1A1 and CYP1A2 by omeprazole. Human and Experimental Toxicology, 18, 95–105.
  • SPINK, D. C., HAYES, C. L., YOUNG, N. R., CHRISTOU, M., SUTTER, T. R., JEFCOATE, C. R. and GIERTHY, J. F., 1994, The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: evidence for induction of a novel 17 beta-estradiol 4-hydroxylase. Journal of Steroid Biochemistry and Molecular Biology, 51, 251–258.
  • WERLINDER, V., BACKLUND, M., ZHUKOV, A. and INGELMAN-SUNDBERG, M., 2001, Transcriptional and post-translational regulation of CYP1A1 by primaquine. Journal of Pharmacology and Experimental Therapeutics, 297, 206–214.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.