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Xenobiotica
the fate of foreign compounds in biological systems
Volume 35, 2005 - Issue 1
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Research Article

Ethnic differences between Japanese and Caucasians in the expression levels of mRNAs for CYP3A4, CYP3A5 and CYP3A7: lack of co-regulation of the expression of CYP3A in Japanese livers

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Pages 69-83 | Received 09 Aug 2004, Published online: 22 Sep 2008

References

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  • Bombail V, Taylor K, Gibson GG, Plant N. 2004. Role of Sp1, C/EBP-, HNF3, and PXR in the basal- and xenobiotic-mediated regulation of the CYP3A4 gene. Drug Metabolism and Disposition 32:525-535. Burk O, Koch I, Raucy J, Hustert E, Eichelbaum M, Brockmo ller J, Zanger UM, Wojnowski L. 2004. The induction of CYP3A5 in human liver and intestine is mediated by the xenobiotic sensors PXR and CAR. Journal of Biological Chemistry 279:38379-38385.
  • Burk O, Tegude H, Koch I, Hustert E, Wolbold R, Glaeser H, Klein K, Fromm MF, Nuessler AK, Neuhaus P, Zanger UM, Eichelbaum M, Wojnowski L. 2002. Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine. Journal of Biological Chemistry 277:24280-24288.

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