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Xenobiotica
the fate of foreign compounds in biological systems
Volume 35, 2005 - Issue 7
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Research Article

Pharmacokinetics and metabolism of acriflavine in rats following intravenous or intramuscular administration of AG60, a mixture of acriflavine and guanosine, a potential antitumour agent

S. Song National Research Laboratory (NRL) of PK/PD, Biotechnology Research Institute, College of Pharmacy, Chungbuk National University, Chungbuk, KoreaCorrespondence[email protected]
,
O. S. Kwon Bioanalysis and Biotransformation Research Center, Korea Institute of Science and Technology, Seoul, Korea
&
Y. B. Chung National Research Laboratory (NRL) of PK/PD, Biotechnology Research Institute, College of Pharmacy, Chungbuk National University, Chungbuk, Korea
Pages 755-773 | Received 21 Feb 2005, Published online: 22 Sep 2008

References

  • Bose S, Gothoskar BP, Ranadive KJ. 1966. Studies of biological macromolecules: II. Effect of acriflavine exposure on the synthesis of macromolecules in liver cells in vivo. Experimental Cell Research 42:89–98.
  • Canellakis ES, Chen TK. 1979. Relationship of biochemical drug effects to their antitumor activity. Biochemical Pharmacology 28:1971–1976.
  • Chakraborty NG, Bose SR, Chowdhury J. 1980. Enhancement of immunogenicity of tumor cells by modification of cell surface with acridine dyes. Indian Journal of Experimental Biology 18:927–930.
  • Ferey L, Herlin F, Marnay J, Mandard A-M, Catania R, Lubet P, Lande R, Bloyet D. 1986. Pararosaniline or acriflavine-Schiff staining of epoxy-embedded tissue periodic acid oxidation in ethanol: A method suitable for morphometric and fluorometric analysis of glycogen. Stain Techniques 61:107–110.
  • Hannun YA, Bell RM. 1988. Aminoacridines, potent inhibitors of protein kinase C. Journal of Biological Chemistry 263:5124–5131.
  • Iigo M, Miwa M, Ishitsuka H, Nitta K. 1987. Potentiation of the chemotherapeutic action of 5'-deoxyfluorouridine in combination with guanosine and related compounds. Cancer Chemotherapy and Pharmacology 19:61–64.
  • Kim SG, Kim CW, Ahn ET, Lee KY, Hong EK, Yoo BI, Han YB. 1997. Enhanced anti-tumor effects of acriflavine in combination with guanosine in mice. Journal of Pharmacy and Pharmacology 49:216–222.
  • Macadam RF, Williamson J. 1974. Drug effects on the fine structure of Trypanosomema rhodisience: Acriflavine, aethidinn, and antrycide. Annals of Tropical Medicine and Parasitology 68:291–299.
  • Mathe G, Pontiggia P, Bourut C, Clenu E, Orbach-Arbouys S. 1994. In vivo eradication of Friend virus as an experimental HIV-model, by combination of zidovudine, acriflavine and an ellipticine analogue: Possible application to the treatment of human pre-AIDS? Biomedicine and Pharmacotherapy 48:51–53.
  • Plakas SM, EL Said KR, Bencsath FA, Musser SM, Hayton WL. 1998. Pharmacokinetics, tissue distribu-tion and metabolism of acriflavine and proflavine in the channel catfish (Ictalurus punctatus). Xenobiotica 28:605–616.
  • Roth D, London M, Manjon M. 1967. Binding specificity and affinity of acriflavine for nucleic acids. Stain Techniques 42:125–132.
  • Yamaoka K, Tanigawara Y, Nakagawa Y, Uno T. 1981. A pharmacokinetic analysis program (MULTI) for microcomputer. Journal of Pharmcobio-Dynamics 4:879–885.
  • Yu Z, Hayton WL, Chan KK. 1997. Characterization of proflavine metabolites in rainbow trout. Drug Metabolism and Disposition 25:431–436.

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