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Xenobiotica
the fate of foreign compounds in biological systems
Volume 35, 2005 - Issue 8
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Research Article

Metabolism of [3H]pentosan polysulfate sodium (PPS) in healthy human volunteers

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Pages 775-784 | Received 05 Apr 2005, Published online: 22 Sep 2008

References

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  • Fellström B, Björklund U, Danielson BG, Eriksson H, Odlind B, Tengblad A. Pentosan polysulfate (ELMIRON®): Pharmacokinetics and effects on the urinary inhibition of crystal growth. Pathogenese und klinik der harnsteine, W Vahlensieck, G Gassner. Steinkopff, Darmstadt 1987; 340–396, editors.
  • Kirkman SK, Hultin TA, Scatina J. Distribution and excretion of 125I-ardeparin, a low molecular weight heparin, in rats and beagle dogs. Drug Metabolism and Disposition 1994; 22: 175–176
  • MacGregor IR, Dawes J, Paton L, Pepper DS, Prowse CV, Smith M. Metabolism of sodium pentosan polysulfate in man — catabolism of iodinated derivatives. Thrombosis and Haemostasis 1984; 51: 321–325
  • Marshall JL, Wellstein A, Rae J, DeLap RJ, Phipps K, Hanfelt J, Yunmbam MK, Sun JX, Duchin KL, Hawkins MJ. Phase I trial of orally administered pentosan polysulfate in patients with advanced cancer. Clinical Cancer Research 1997; 3: 2347–2354
  • Odlind B, Dencker L, Tengblad A. Preferential localization of 3H-pentosanpolysulfate to the urinary tract in rats. Pharmacology and Toxicology 1987; 61: 162–166

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