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Xenobiotica
the fate of foreign compounds in biological systems
Volume 35, 2005 - Issue 10-11
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Research Article

CCAAT/enhancer binding protein activation by PD98059 contributes to the inhibition of AhR-mediated 3-methylcholanthrene induction of CYP1A1

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Pages 975-987 | Received 24 Jun 2005, Published online: 22 Sep 2008

References

  • Ahn S, Olive M, Aggarwal S, Krylov D, Ginty DD, Vinson C. A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos. Molecular and Cellular Biology 1998; 18: 967–977
  • Andrieux L, Langouet S, Fautrel A, Ezan F, Krauser JA, Savouret JF, Guengerich FP, Baffet G, Guillouzo A. Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes. Molecular Pharmacology 2004; 65: 934–943
  • Backlund M, Johansson I, Mkrtchian S, Ingelman-Sundberg M. Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells. Journal of Biological Chemistry 1997; 272: 31755–31763
  • Beischlag TV, Wang S, Rose DW, Torchia J, Reisz-Porszasz S, Khurshid M, Nelson WE, Probst MR, Rosenfeld MG, Hankinson O. Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex. Molecular and Cellular Biology 2002; 22: 4319–4333
  • Carrier F, Chang CY, Duh JL, Nebert DW, Puga A. Interaction of the regulatory domains of the murine Cyp1a1 gene with two DNA-binding proteins in addition to the Ah receptor and the Ah receptor nuclear translocator (ARNT). Biochemical Pharmacology 1994; 48: 1767–1778
  • Cho IJ, Kim SG. Oltipraz inhibits 3-methylcholanthrene induction of CYP1A1 by CCAAT/enhancer-binding protein activation. Journal of Biological Chemistry 2003; 278: 44103–44112
  • Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proceedings of the National Academy of Sciences. USA 1995; 92: 7686–7689
  • Hankinson O. The aryl hydrocarbon receptor complex. Annual Review of Pharmacology and Toxicology 1995; 35: 307–340
  • Hollman PC, Katan MB. Health effects bioavailability of dietary flavonols. Free Radical Research 1999; 31: S75–S80
  • Kang KW, Park EY, Kim SG. Activation of CCAAT/enhancer-binding protein β by 2′-amino-3′-methoxyflavone (PD98059) leads to the induction of glutathione S-transferase A2. Carcinogenesis 2003a; 24: 475–482
  • Kang KW, Cho IJ, Lee CH, Kim SG. Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/enhancer binding protein β activation in the induction of glutathione S-transferase by oltipraz. Journal of the National Cancer Institute 2003b; 95: 53–66
  • Kobayashi A, Numayama-Tsuruta K, Sogawa K, Fujii-Kuriyama Y. CBP/p300 functions as a possible transcriptional coactivator of Ah receptor nuclear translocator (Arnt). Journal of Biochemistry 1997; 122: 703–710
  • Le Ferrec E, Lagadic-Gossmann D, Rauch C, Bardiau C, Maheo K, Massiere F, Le Vee M, Guillouzo A, Morel F. Transcriptional induction of CYP1A1 by oltipraz in human Caco-2 cells is aryl hydrocarbon receptor- and calcium-dependent. Journal of Biological Chemistry 2002; 277: 24780–24787
  • Lewis DFV. P450 substrate specificity and metabolism. Cytochromes P450: Structure, function, and metabolism, DFV Lewis. Informa UK Ltd, Bristol, PA 1996; 115–168
  • Nguyen TA, Hoivik D, Lee JE, Safe S. Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex. Archives of Biochemistry and Biophysics 1999; 367: 250–257
  • Park HJ, Kim BC, Kim SJ, Choi KS. Role of MAP kinases and their cross-talk in TGFß1-induced apoptosis in FaO rat hepatoma cell line. Hepatology 2002; 35: 1360–1371
  • Reiners JJ, Jr, Clift R, Mathieu P. Suppression of cell cycle progression by flavonoids: Dependence on the aryl hydrocarbon receptor. Carcinogenesis 1999; 20: 1561–1566
  • Reiners JJ, Jr, Lee JY, Clift RE, Dudley DT, Myrand SP. PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase. Molecular Pharmacology 1998; 53: 438–445
  • Rowlands JC, Gustafsson JA. Aryl hydrocarbon receptor-mediated signal transduction. Critical Reviews in Toxicology 1997; 27: 109–134
  • Schreiber E, Harshman K, Kemler I, Malipiero U, Schaffner W, Fontana A. Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins. Nucleic Acids Research 1990; 18: 5495–5503
  • Sogawa K, Fujisawa-Sehara A, Yamane M, Fujii-Kuriyama Y. Location of regulatory elements responsible for drug induction in the rat cytochrome P-450c gene. Proceedings of the National Academy of Sciences. USA 1986; 83: 8044–8048
  • Vasiliou V, Shertzer HG, Liu RM, Sainsbury M, Nebert DW. Response of [Ah] battery genes to compounds that protect against menadione toxicity. Biochemical Pharmacology 1995; 50: 1885–1891
  • Wen X, Walle UK, Walle T. 5,7-Dimethoxyflavone downregulates CYP1A1 expression and benzo[a]pyrene-induced DNA binding in HepG2 cells. Carcinogenesis 2005; 26: 803–809
  • Yim S, Oh M, Choi SM, Park H. Inhibition of the MEK-1/p42 MAP kinase reduces aryl hydrocarbon receptor–DNA interactions. Biochemical and Biophysical Research Communications 2004; 322: 9–16
  • Zhang JW, Tang QQ, Vinson C, Lane MD. Dominant-negative C/EBP disrupts mitotic clonal expansion and differentiation of 3T3-L1 preadipocytes. Proceedings of the National Academy of Sciences. USA 2004; 101: 43–47

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