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Xenobiotica
the fate of foreign compounds in biological systems
Volume 37, 2007 - Issue 9
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Research Article

Identification and characterization of two chloramphenicol glucuronides from the in vitro glucuronidation of chloramphenicol in human liver microsomes

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Pages 954-971 | Received 18 Jun 2007, Accepted 09 Aug 2007, Published online: 22 Sep 2008

References

  • Brock TD. Chloramphenicol. Bacteriological Reviews 1961; 25: 32–48
  • Brook I. Management of anaerobic infection. Expert Review of Anti-infective Therapy 2004; 2: 153–158
  • Chambers HF. Protein synthesis inhibitors and miscellaneous antibacterial agents. Goodman and Gilman's the pharmacological basis of therapeutics11th, LL Brunton, JS Lazo, KL Parker. McGraw-Hill, New York, NY 2006; 1179–1182
  • Cornish-Bowden A. Fundamentals of enzyme kinetics3rd. Portland, London 2004; 113–144
  • Craft AW, Brocklebank JT, Hey EN, Jackson RH. The ‘grey toddler’. Chloramphenicol toxicity. Archives of Disease in Childhood 1974; 49: 235–237
  • Cunningham RF, Israili ZH, Dayton PG. Clinical pharmacokinetics of probenecid. Clinical Pharmacokinetics 1981; 6: 135–151
  • Dayton PG, Yu TF, Chen W, Berger L, West LA, Gutman AB. The physiological disposition of probenecid, including renal clearance, in man, studied by an improved method for its estimation in biological material. Journal of Pharmacology and Experimental Therapeutics 1963; 140: 278–286
  • Glazko AJ. Identification of chloramphenicol metabolites and some factors affecting metabolic disposition. Antimicrobial Agents and Chemotherapy 1966; 6: 655–665
  • Glazko AJ. Early adventures in drug metabolism. 3. Chloramphenicol. Therapeutic Drug Monitoring 1987; 9: 320–330
  • Holt D, Harvey D, Hurley R. Chloramphenicol toxicity. Adverse Drug Reactions and Toxicological Reviews 1993; 12: 83–95
  • Houston JB, Kenworthy KE. In vitro–in vivo scaling of CYP kinetic data not consistent with the classical Michaelis–Menten model. Drug Metabolism and Disposition 2000; 28: 246–254
  • Hutzler JM, Tracy TS. Atypical kinetic profiles in drug metabolism reactions. Drug Metabolism and Disposition 2002; 30: 355–362
  • Kaji H, Kume T. Characterization of afloqualone N-glucuronidation: Species differences and identification of human UDP-glucuronosyltransferase isoform(s). Drug Metabolism and Disposition 2005; 33: 60–67
  • Lam RF, Lai JSM, Ng JSK, Rao SK, Law RWK, Lam DSC. Topical chloramphenicol for eye infections. Hong Kong Medical Journal 2002; 8: 44–47
  • Matsui M, Okada M. Studies on the glucaric acid pathway in the metabolism of D-glucuronic acid in mammals. II. Excretion of D-glucaric acid in urine after administration of several monosaccharides and their derivatives to mammals. Chemistry and Pharmacology Bulletin 1970; 18: 21–29
  • McLafferty FW, Turecek F. Interpretation of mass spectra4th. University Science Books, Sausalito, CA 1993; 19–23, USA
  • National Toxicology Program. Tenth report on carcinogens: Chloramphenicol. Report on Carcinogens 2002; 10: 48–50
  • Oatis JE, Jr, McCarthy JR, Knapp DR. Synthesis and chromatographic separation of the glucuronides of (R)- and (S)-propranolol. Journal of Medical Chemistry 1983; 26: 1687–1691
  • Prasad K, Singhal T, Jain N, Gupta PK. Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis. Cochrane Database of Systematic Reviews 2004; 2: CD001832
  • Reis JN, Lima JB, Ribeiro GS, Corderio SM, Salgado Katia, Reis MG, Ko AI. Antimicrobial resistance in Haemophilus influenzae isolated during population-based surveillance for meningitis. Antimicrobial Agents and Chemotherapy 2002; 46: 3641–3643
  • Shou M, Lin Y, Lu P, Tang C, Mei Q, Cui D, Tang W, Ngui JS, Lin CC, Singh R, et al. Enzyme kinetics of cytochrome P450-mediated reactions. Current Drug Metabolism 2001; 2: 17–36
  • Simons PJ, Cockshott ID, Glen JB, Gordon EA, Knott S, Ruane RJ. Disposition and pharmacology of propofol glucuronide administered intravenously to animals. Xenobiotica 1992; 22: 1267–1273
  • Suhrland LG, Weisberger AS. Chloramphenicol toxicity in liver renal disease. Archives of Internal Medicine 1963; 112: 747–754
  • Venkatakrishnan K, Von Moltke LL, Greenblatt DJ. Application of the relative activity factor approach in scaling from heterologously expressed cytochromes p450 to human liver microsomes: Studies on amitriptyline as a model substrate. Journal of Pharmacology and Experimental Therapeutics 2001; 297: 326–337
  • Weiss CF, Glazko AJ, Weston JK. Chloramphenicol in the newborn infant. A physiologic explanation of its toxicity when given in excessive doses. New England Journal of Medicine 1960; 262: 787–794

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