References
- Anderson ME, Siahaan TJ. Targeting ICAM-1/LFA-1 interaction for controlling autoimmune diseases: Designing peptide and small molecule inhibitors. Peptides 2003; 24: 487–501
- Beaumont K, Webster R, Gardner I, Dack K. Design of ester prodrugs to enhance oral absorption of poorly permeable compounds: Challenges to the discovery scientist. Current Drug Metabolism 2003; 4: 461–485
- Burdick DJ, Marsters JC, Jr, Aliagas-Martin I, Stanley M, Beresini M, Clark K, McDowell RS, Gadek TR. N-benzoyl amino acids as ICAM/LFA-1 inhibitors. Part 2: Structure–activity relationship of the benzoyl moiety. Bioorganic and Medicinal Chemistry Letters 2004; 14(9)2055–2059
- Burdick DJ, Paris K, Weese K, Stanley M, Beresini M, Clark K, McDowell RS, Marsters JC, Gadek TR. N-benzoyl amino acids as LFA-1/ICAM inhibitors 1: Amino acid structure–activity relationship. Bioorganic and Medicinal Chemistry Letters 2003; 13: 1015–1018
- Emeigh J, Gao DA, Goldberg DR, Kuzmich D, Miao C, Potocki I, Qian KC, Sorcek RJ, Jeanfavre DD, et al. Second-generation lymphocyte function-associated antigen-1 inhibitors: 1H-imidazo[1,2-a]imidazol-2-one derivatives. Journal of Medicinal Chemistry 2004; 47: 5356–5366
- Gachon F, Nicolas C, Maurizis JC, Verny M, Chabard JL, Faurie M, Gaillard G. Disposition and metabolism of letosteine in rats. Drug Metabolism and Disposition 1988; 16: 853–857
- Gadek TR, Burdick DJ, McDowell RS, Stanley MS, Marsters JC, Paris KJ, Oare DA, Reynolds ME, Ladner C, Zioncheck KA, et al. Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule. Science 2002; 295: 1086–1089
- Gudmundsson OS, Pauletti GM, Wang W, Shan D, Zhang H, Wang B, Borchardt RT. Coumarinic acid-based cyclic prodrugs of opioid peptides that exhibit metabolic stability to peptidases and excellent cellular permeability. Pharmaceutical Research 1999; 16: 7–15
- Keating S, Clark K, Stefanich L, Arellano F, Edwards C, Bodary, Spencer S, Gadek T, Marsters J, Jr, Beresini M. Competition between intercellular adhesion molecule-1 and a small-molecule antagonist for a common binding site on the alpha subunit of lymphocyte function associated antigen-1. Protein Science 2006; 15: 290–303
- Liu L, Link JT, Pei Z, Reilly EB, Leitza S, Nguyen B, Marsh KC, Okasinski GF, Von Geldern TW, Ormes M, et al. Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 1. Identification of an additional binding pocket based on an anilino diaryl sulfide lead. Journal of Medicinal Chemistry 2000; 43: 4025–4040
- National Institutes of Health National Research Council. Guide for the Care and Use of Laboratory Animals. 1996
- Roberts J. Amino acids and their derivatives as radioprotective agents. Amino Acids 1992; 3: 25–52
- Yonekawa K, Harlan JM. Targeting leukocyte integrins in human diseases. Journal of Leukocyte Biology 2005; 77: 129–140