Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 47, 2017 - Issue 8
307
Views
14
CrossRef citations to date
0
Altmetric
Clinical Pharmacokinetics and Metabolism

Population pharmacokinetics of mycophenolic acid and its glucuronide metabolite in lung transplant recipients with and without cystic fibrosis

, , , , &
Pages 697-704 | Received 24 May 2016, Accepted 16 Jul 2016, Published online: 10 Aug 2016

References

  • Benoit-Biancamano MO, Caron P, Levesque E, et al. (2007). Sensitive high-performance liquid chromatography-tandem mass spectrometry method for quantitative analysis of mycophenolic acid and its glucuronide metabolites in human plasma and urine. J Chromatogr B Analyt Technol Biomed Life Sci 858:159–67
  • Bullingham RE, Nicholls AJ, Kamm BR. (1998). Clinical pharmacokinetics of mycophenolate mofetil. Clin Pharmacokinet 34:429–55
  • Christie JD, Edwards LB, Kucheryavaya AY, et al. (2011). The registry of the international society for heart and lung transplantation: twenty-eighth adult lung and heart-lung transplant report–2011. J Heart Lung Transplant 30:1104–22
  • Colom H, Lloberas N, Andreu F, et al. (2014). Pharmacokinetic modeling of enterohepatic circulation of mycophenolic acid in renal transplant recipients. Kidney Int 85:1434–43
  • Cremers S, Schoemaker R, Scholten E, et al. (2005). Characterizing the role of enterohepatic recycling in the interactions between mycophenolate mofetil and calcineurin inhibitors in renal transplant patients by pharmacokinetic modelling. Br J Clin Pharmacol 60:249–56
  • de Winter BC, Monchaud C, Premaud A, et al. (2012). Bayesian estimation of mycophenolate mofetil in lung transplantation, using a population pharmacokinetic model developed in kidney and lung transplant recipients. Clin Pharmacokinet 51:29–39
  • Debray D, Rainteau D, Barbu V, et al. (2012). Defects in gallbladder emptying and bile acid homeostasis in mice with cystic fibrosis transmembrane conductance regulator deficiencies. Gastroenterology. 142:1581–91 e6
  • Fujiyama N, Miura M, Kato S, et al. (2010). Involvement of carboxylesterase 1 and 2 in the hydrolysis of mycophenolate mofetil. Drug Metab Dispos 38:2210–17
  • Gerbase MW, Fathi M, Spiliopoulos A, et al. (2003). Pharmacokinetics of mycophenolic acid associated with calcineurin inhibitors: long-term monitoring in stable lung recipients with and without cystic fibrosis. J Heart Lung Transplant 22:587–90
  • Johnson HJ, Swan SK, Heim-Duthoy KL, et al. (1998). The pharmacokinetics of a single oral dose of mycophenolate mofetil in patients with varying degrees of renal function. Clin Pharmacol Ther 63:512–18
  • Ling J, Shi J, Jiang Q, Jiao Z. (2014). Population pharmacokinetics of mycophenolic acid and its main glucuronide metabolite: a comparison between healthy Chinese and Caucasian subjects receiving mycophenolate mofetil. Eur J Clin Pharmacol 71:95–106
  • Pittman FE, Denning CR, Barker HG. (1964). Albumin metabolism in cystic fibrosis. Am J Dis Child 108:360–5
  • Quattrucci S, Rolla M, Cimino G, et al. (2005). Lung transplantation for cystic fibrosis: 6-year follow-up. J Cyst Fibros 4:107–14
  • Boucher RC, (2012). Chapter 259. Cystic fibrosis. In: Longo DL, Fauci AS, Kasper DL eds. Harrison's principles of internal medicine. 18th ed.New York, NY: McGraw-Hill Inc. 1194–7
  • Rey E, Treluyer JM, Pons G. (1998). Drug disposition in cystic fibrosis. Clin Pharmacokinet 35:313–29
  • Sam WJ, Akhlaghi F, Rosenbaum SE. (2009). Population pharmacokinetics of mycophenolic acid and its 2 glucuronidated metabolites in kidney transplant recipients. J Clin Pharmacol 49:185–95
  • Savic RM, Karlsson MO. (2009). Importance of shrinkage in empirical bayes estimates for diagnostics: problems and solutions. AAPS J 11:558–69
  • Shum B, Duffull SB, Taylor PJ, Tett SE. (2003). Population pharmacokinetic analysis of mycophenolic acid in renal transplant recipients following oral administration of mycophenolate mofetil. Br J Clin Pharmacol 56:188–97
  • Staatz CE, Tett SE. (2007). Clinical pharmacokinetics and pharmacodynamics of mycophenolate in solid organ transplant recipients. Clin Pharmacokinet 46:13–58
  • Stead RJ, Houlder S, Agnew J, et al. (1988). Vitamin D and parathyroid hormone and bone mineralisation in adults with cystic fibrosis. Thorax 43:190–4
  • Strober W, Peter G, Schwartz RH. (1969). Albumin metabolism in cystic fibrosis. Pediatrics 43:416–26
  • Stuckey L, Clark Ojo T, Park JM, et al. (2014). Mycophenolic acid pharmacokinetics in lung transplant recipients with cystic fibrosis. Ther Drug Monit 36:148–51
  • Sugioka N, Sasaki T, Kokuhu T, et al. (2006). Clinical pharmacokinetics of mycophenolate mofetil in Japanese renal transplant recipients: a retrospective cohort study in a single center. Biol Pharm Bull 29:2099–105
  • Ting LS, Partovi N, Levy RD, et al. (2006). Pharmacokinetics of mycophenolic acid and its glucuronidated metabolites in stable lung transplant recipients. Ann Pharmacother 40:1509–16
  • van Hest RM, Mathot RA, Pescovitz MD, et al. (2006). Explaining variability in mycophenolic acid exposure to optimize mycophenolate mofetil dosing: a population pharmacokinetic meta-analysis of mycophenolic acid in renal transplant recipients. J Am Soc Nephrol 17:871–80
  • van Hest RM, van Gelder T, Vulto AG, Mathot RA. (2005). Population pharmacokinetics of mycophenolic acid in renal transplant recipients. Clin Pharmacokinet 44:1083–96
  • Wang X, Kay A, Anak O, et al. (2013). Population pharmacokinetic/pharmacodynamic modeling to assist dosing schedule selection for dovitinib. J Clin Pharmacol 53:14–20
  • Wang XX, Feng MR, Nguyen H, et al. (2015). Population pharmacokinetics of mycophenolic acid in lung transplant recipients with and without cystic fibrosis. Eur J Clin Pharmacol 71:673–9
  • Woillard JB, Rerolle JP, Picard N, et al. (2010). Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele. Br J Clin Pharmacol 69:675–83

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.