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Xenobiotica
the fate of foreign compounds in biological systems
Volume 48, 2018 - Issue 4
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Animal Pharmacokinetics and Metabolism

Influence of grapefruit juice on pharmacokinetics of triptolide in rats grapefruit juice on the effects of triptolide

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Pages 407-411 | Received 26 Feb 2017, Accepted 27 Mar 2017, Published online: 16 Apr 2017

References

  • Bailey DG, Dresser GK. (2004). Interactions between grapefruit juice and cardiovascular drugs. Am J Cardiovasc Drugs 4:281–97
  • Bailey DG, Dresser GK, Leake BF, Kim RB. (2007). Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice. Clin Pharmacol Ther 81:495–502
  • Brinker AM, Raskin I. (2005). Determination of triptolide in root extracts of Tripterygium wilfordii by solid-phase extraction and reverse-phase high-performance liquid chromatography. J Chromatogr A 1070:65–70
  • Cheng S, LeBlanc KJ, Li L. (2014). Triptolide preserves cognitive function and reduces neuropathology in a mouse model of Alzheimer's disease. PLoS One 9:e108845
  • Cuong BT, Binh VQ, Dai B, et al. (2006). Does gender, food or grapefruit juice alter the pharmacokinetics of primaquine in healthy subjects? Br J Clin Pharmacol 61:682–9
  • Dahan A, Amidon GL. (2009). Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein. Pharm Res 26:883–92
  • Fukazawa I, Uchida N, Uchida E, Yasuhara H. (2004). Effects of grapefruit juice on pharmacokinetics of atorvastatin and pravastatin in Japanese. Br J Clin Pharmacol 57:448–55
  • Grenier J, Fradette C, Morelli G, et al. (2006). Pomelo juice, but not cranberry juice, affects the pharmacokinetics of cyclosporine in humans. Clin Pharmacol Ther 79:255–62
  • Honda Y, Ushigome F, Koyabu N, et al. (2004). Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux. Br J Pharmacol 143:856–64
  • Hu J, Shang D, Xu X, et al. (2016). Effect of grapefruit juice and food on the pharmacokinetics of pirfenidone in healthy Chinese volunteers: a diet-drug interaction study. Xenobiotica 46:516–21
  • Jin MC, Chen XH, OuYang XK. (2009). Simultaneous determination of triptolide, tripdiolide and tripterine in human urine by high-performance liquid chromatography coupled with ion trap atmospheric-pressure chemical ionization mass spectrometry. Biomed Chromatogr 23:289–94
  • Kumar A, Corey C, Scott I, et al. (2016). Minnelide/triptolide impairs mitochondrial function by regulating SIRT3 in P53-dependent manner in non-small cell lung cancer. PLoS One 11:e0160783
  • Lee JW, Morris JK, Wald NJ. (2016). Grapefruit juice and statins. Am J Med 129:26–9
  • Li H, Hui L, Xu W, et al. (2012). Triptolide modulates the sensitivity of K562/A02 cells to adriamycin by regulating miR-21 expression. Pharm Biol 50:1233–40
  • Li XJ, Jiang ZZ, Zhang LY. (2014). Triptolide: progress on research in pharmacodynamics and toxicology. J Ethnopharmacol 155:67–79
  • Liu L, Jiang Z, Liu J, et al. (2010). Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats. Toxicology 271:57–63
  • Luo H, Zhao L, Leung J, et al. (2016). Routine pre-procedural rectal indometacin versus selective post-procedural rectal indometacin to prevent pancreatitis in patients undergoing endoscopic retrograde cholangiopancreatography: a multicentre, single-blinded, randomised controlled trial. Lancet 387:2293–301
  • Nakagawa K, Goto T. (2010). Effects of ingestion of grapefruit juice or grapefruit on the hypotensive effect and plasma concentrations of dihydropyridine calcium antagonists (amlodipine and nifedipine): a case study. Clin Exp Hypertens 32:71–5
  • Ni B, Jiang Z, Huang X, et al. (2008). Male reproductive toxicity and toxicokinetics of triptolide in rats. Arzneimittelforschung 58:673–80
  • Ravi PR, Vats R, Thakur R, et al. (2012). Effect of grapefruit juice and ritonavir on pharmacokinetics of lopinavir in Wistar rats. Phytother Res 26:1490–5
  • Shao F, Wang G, Xie H, et al. (2007). Pharmacokinetic study of triptolide, a constituent of immunosuppressive Chinese herb medicine, in rats. Biol Pharm Bull 30:702–7
  • Shen G, Zhuang X, Xiao W, et al. (2014). Role of CYP3A in regulating hepatic clearance and hepatotoxicity of triptolide in rat liver microsomes and sandwich-cultured hepatocytes. Food Chem Toxicol 71:90–6
  • Soldner A, Christians U, Susanto M, et al. (1999). Grapefruit juice activates P-glycoprotein-mediated drug transport. Pharm Res 16:478–85
  • Tai T, Huang X, Su Y, et al. (2014). Glycyrrhizin accelerates the metabolism of triptolide through induction of CYP3A in rats. J Ethnopharmacol 152:358–63
  • Vandermolen KM, Cech NB, Paine MF, Oberlies NH. (2013). Rapid quantitation of furanocoumarins and flavonoids in grapefruit juice using ultra-performance liquid chromatography. Phytochem Anal 24:654–60
  • Wang X, Zhang X, Huang X, et al (2015). The drug-drug interaction of sorafenib mediated by P-glycoprotein and CYP3A4. Xenobiotica 46:651–8
  • Xie CQ, Zhou P, Zuo J, et al. (2016). Triptolide exerts pro-apoptotic and cell cycle arrest activity on drug-resistant human lung cancer A549/Taxol cells via modulation of MAPK and PI3K/Akt signaling pathways. Oncol Lett 12:3586–90
  • Yao J, Zhang L, Zhao X, et al. (2006). Simultaneous determination of triptolide, wilforlide A and triptonide in human plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry. Biol Pharm Bull 29:1483–6
  • Zhang H, Wu Q, Li W, et al. (2014). Absorption and metabolism of three monoester-diterpenoid alkaloids in Aconitum carmichaeli after oral administration to rats by HPLC-MS. J Ethnopharmacol 154:645–52
  • Zhang Y, Li J, Lei X, et al. (2016). Influence of verapamil on pharmacokinetics of triptolide in rats. Eur J Drug Metab Pharmacokinet 41:449–56
  • Zhuang XM, Shen GL, Xiao WB, et al. (2013). Assessment of the roles of P-glycoprotein and cytochrome P450 in triptolide-induced liver toxicity in sandwich-cultured rat hepatocyte model. Drug Metab Dispos 41:2158–65

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